Detalhe da pesquisa
1.
Design of Aminobenzothiazole Inhibitors of Rho Kinases 1 and 2 by Using Protein Kinaseâ A as a Structure Surrogate.
Chembiochem
; 19(6): 613-621, 2018 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29314498
2.
Synthesis and SAR of 4-aminocyclopentapyrrolidines as N-type Ca²âº channel blockers with analgesic activity.
Bioorg Med Chem
; 20(13): 4128-39, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22626552
3.
Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives.
Bioorg Med Chem Lett
; 20(22): 6812-5, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20855211
4.
Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Na(v)1.8 sodium channel with efficacy in a model of neuropathic pain.
Bioorg Med Chem
; 18(22): 7816-25, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20965738
5.
Near infrared readouts offer sensitive and rapid assessments of intestinal permeability and disease severity in inflammatory bowel disease models.
Sci Rep
; 10(1): 4696, 2020 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32170183
6.
A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats.
Biochem Pharmacol
; 83(3): 406-18, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22153861
7.
Potentiation of analgesic efficacy but not side effects: co-administration of an α4ß2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in experimental models of pain in rats.
Biochem Pharmacol
; 82(8): 967-76, 2011 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21620806
8.
Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation.
Pain
; 152(5): 1165-1172, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21402443
9.
Characterization of Fasudil in preclinical models of pain.
J Pain
; 11(10): 941-9, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20338818
10.
Comparison of mechanical allodynia and the affective component of inflammatory pain in rats.
Neuropharmacology
; 58(2): 537-43, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19703478