Detalhe da pesquisa
1.
Characterization of anti-GASP motif antibodies that inhibit the interaction between GPRASP1 and G protein-coupled receptors.
Anal Biochem
; 665: 115062, 2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36731712
2.
Neuropeptide FF and prolactin-releasing peptide decrease cortical excitability through activation of NPFF receptors.
Epilepsia
; 56(3): 489-98, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25684325
3.
Rapid and scalable synthesis of innovative unnatural α,ß or γ-amino acids functionalized with tertiary amines on their side-chains.
Org Biomol Chem
; 13(25): 7020-6, 2015 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26030164
4.
Multitarget µ-Opioid Receptor AgonistsâNeuropeptide FF Receptor Antagonists Induce Potent Antinociception with Reduced Adverse Side Effects.
J Med Chem
; 67(9): 7603-7619, 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38687204
5.
Development of sub-nanomolar dipeptidic ligands of neuropeptide FF receptors.
Bioorg Med Chem Lett
; 22(24): 7471-4, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23131340
6.
Behavioral characterization, potential clinical relevance and mechanisms of latent pain sensitization.
Pharmacol Ther
; 233: 108032, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34763010
7.
GPRASP/ARMCX Protein Family: Potential Involvement in Health and Diseases Revealed by their Novel Interacting Partners.
Curr Top Med Chem
; 21(3): 227-254, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33267763
8.
Comprehensive overview of biased pharmacology at the opioid receptors: biased ligands and bias factors.
RSC Med Chem
; 12(6): 828-870, 2021 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34223156
9.
Identification of an N-acylated-DArg-Leu-NH2 Dipeptide as a Highly Selective Neuropeptide FF1 Receptor Antagonist That Potently Prevents Opioid-Induced Hyperalgesia.
J Med Chem
; 64(11): 7555-7564, 2021 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34008968
10.
Prolactin-releasing peptide effects in the rat brain are mediated through the Neuropeptide FF receptor.
Eur J Neurosci
; 30(8): 1585-93, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19821834
11.
Attenuated behavioural responses to acute and chronic cocaine in GASP-1-deficient mice.
Eur J Neurosci
; 30(5): 860-8, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19712096
12.
Aminoguanidine Hydrazone Derivatives as Nonpeptide NPFF1 Receptor Antagonists Reverse Opioid Induced Hyperalgesia.
ACS Chem Neurosci
; 9(11): 2599-2609, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29727163
13.
A bifunctional-biased mu-opioid agonist-neuropeptide FF receptor antagonist as analgesic with improved acute and chronic side effects.
Pain
; 159(9): 1705-1718, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-29708942
14.
Morphine-induced hyperalgesia involves mu opioid receptors and the metabolite morphine-3-glucuronide.
Sci Rep
; 7(1): 10406, 2017 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28871199
15.
RF313, an orally bioavailable neuropeptide FF receptor antagonist, opposes effects of RF-amide-related peptide-3 and opioid-induced hyperalgesia in rodents.
Neuropharmacology
; 118: 188-198, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28288815
16.
Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages.
J Clin Invest
; 127(7): 2842-2854, 2017 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28581443
17.
RF-amide neuropeptides and their receptors in Mammals: Pharmacological properties, drug development and main physiological functions.
Pharmacol Ther
; 160: 84-132, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26896564
18.
Opioid-induced hyperalgesia: Cellular and molecular mechanisms.
Neuroscience
; 338: 160-182, 2016 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27346146
19.
Development of Dipeptidic hGPR54 Agonists.
ChemMedChem
; 11(19): 2147-2154, 2016 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27562608
20.
Bifunctional Peptide-Based Opioid Agonist-Nociceptin Antagonist Ligands for Dual Treatment of Acute and Neuropathic Pain.
J Med Chem
; 59(8): 3777-92, 2016 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27035422