Detalhe da pesquisa
1.
Advanced molecular imaging for the characterisation of complex medicines.
Drug Discov Today
; 27(6): 1716-1723, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35257858
2.
Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicity in normal tissues.
Theranostics
; 10(24): 10973-10992, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33042265
3.
Organ-on-a-chip technology: turning its potential for clinical benefit into reality.
Drug Discov Today
; 24(5): 1217-1223, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30880172
4.
The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor suitable for intravenous dosing.
Bioorg Med Chem Lett
; 18(24): 6369-73, 2008 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18996007
5.
High-content assays in oncology drug discovery: opportunities and challenges.
IDrugs
; 11(6): 422-7, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18509783
6.
Methacholine and PDGF activate store-operated calcium entry in neuronal precursor cells via distinct calcium entry channels.
Biol Res
; 41(2): 183-95, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18949136
7.
Automated cell plating and sample treatments for fixed cells in high content assays.
Methods Mol Biol
; 356: 109-19, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-16988398
8.
IMI European Lead Factory - democratizing access to high-throughput screening.
Nat Rev Drug Discov
; 21(4): 245-246, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34907316
9.
Measurement and analysis of calcium signaling in heterogeneous cell cultures.
Methods Enzymol
; 414: 335-47, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-17110201
10.
A morphology- and kinetics-based cascade for human neural cell high content screening.
Assay Drug Dev Technol
; 4(2): 143-52, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16712418
11.
Open innovation in early drug discovery: roadmaps and roadblocks.
Drug Discov Today
; 21(5): 779-88, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26743597
12.
A new pyridazine series of GABAA alpha5 ligands.
J Med Chem
; 48(19): 6004-11, 2005 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-16162003
13.
High content kinetic assays of neuronal signaling implemented on BD pathway HT.
Assay Drug Dev Technol
; 3(6): 623-36, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16438658
14.
A high-throughput assay for modulators of ligand-gated chloride channels.
Assay Drug Dev Technol
; 3(1): 59-64, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15798396
15.
What makes a drug discovery consortium successful?
Nat Rev Drug Discov
; 19(11): 737-738, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32350459
16.
Multiple structural features of steroids mediate subtype-selective effects on human alpha4beta3delta GABAA receptors.
Biochem Pharmacol
; 68(5): 819-31, 2004 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15294445
17.
Quantitative assays of chemotaxis and chemokinesis for human neural cells.
Assay Drug Dev Technol
; 2(5): 465-72, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15671644
18.
Native and recombinant human Edg4 receptor-mediated Ca(2+) signalling.
Assay Drug Dev Technol
; 1(1 Pt 1): 31-40, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15090154
19.
Estrogen receptor ligands affect mitochondrial activity in SH-SY5Y human neuroblastoma cells.
Neuroreport
; 13(7): 957-60, 2002 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-12004198
20.
New directions in kinetic high information content assays.
Drug Discov Today
; 11(5-6): 237-44, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16639807