Initial experience with orbital atherectomy in a tertiary centre in the Netherlands.

BACKGROUND: In January 2021, the Diamondback 360 orbital atherectomy (OA) system received CE mark approval and became available in Europe. The first procedure in Europe was performed at the Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands. AIMS: To report the procedural safety and efficacy of the initial experience with OA in a tertiary care institution in the Netherlands. METHODS: Patients with de novo severely calcified coronary artery disease who were treated with intended invasive imaging-guided OA were included in a prospective single-centre registry. Device success, defined as less than 50% stenosis after OA, and procedural success, defined as successful stent implantation with less than 50% residual stenosis, were evaluated. Calcium debulking effects were assessed by invasive imaging. Safety was assessed up to 30 days after the index procedure. RESULTS: Between February 2021 and June 2021, 29 patients with a total of 39 coronary arteries underwent OA. Target lesions were heavily calcified with a mean length of 32 mm and a calcium arc of 320 degrees. Invasive imaging was applied in all but one patient and 36 vessels. Superficial sanding was observed in almost all vessels (90%) and fracturing of deeper medial calcium in more than half of the vessels (63%), with a device success of 66% and procedural success of 94%. The mean stent symmetry index was 0.84, indicating good circular stent expansion. No primary safety events occurred during 30 days of follow-up. CONCLUSION: Our initial experience with OA for heavily calcified coronary lesions demonstrated favourable debulking effects and plaque modification, with high procedural success and clinical safety.

Imaging Guided Treatment of Bifurcation Lesions, Implications on Daily Practice.

Treating coronary bifurcation lesions can always be challenging. Choice of bifurcation technique depends firstly on the complexity of the lesion but also on operators experience and skills. Occasionally, switching from one technique to another, during the course of the procedure, will be needed and this requires adequate knowledge of the procedural steps for each technique. Intravascular imaging enables the operator to choose between one or two stents strategy and offers guidance during the procedure. A patient was treated at our institution with three different bifurcation techniques while a switch to a two stent bifurcation technique was required, intravascular ultrasound guidance was available before and during the procedure. Choice of bifurcation strategy was based on imaging information acquired and after the completion of each bifurcation technique the bifurcation sites were recorded and analyzed.