Detalhe da pesquisa
1.
Effect of HBB genotype on survival in a cohort of transfusion-dependent thalassemia patients in Cyprus.
Haematologica
; 106(9): 2458-2468, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32732363
2.
Distinct miRNA Signatures and Networks Discern Fetal from Adult Erythroid Differentiation and Primary from Immortalized Erythroid Cells.
Int J Mol Sci
; 22(7)2021 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33807258
3.
Relative and Absolute Quantification of Aberrant and Normal Splice Variants in HBBIVSI-110 (G > A) ß-Thalassemia.
Int J Mol Sci
; 21(18)2020 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32933098
4.
A novel mutation in the erythroid transcription factor KLF1 is likely responsible for ameliorating ß-thalassemia major.
Hum Mutat
; 40(10): 1768-1780, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31115947
5.
Sex-specific transcriptional profiles identified in ß-thalassemia patients.
Haematologica
; 106(4): 1207-1211, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32817281
6.
Correction of IVS I-110(G>A) ß-thalassemia by CRISPR/Cas-and TALEN-mediated disruption of aberrant regulatory elements in human hematopoietic stem and progenitor cells.
Haematologica
; 104(11): e497-e501, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31004018
7.
Context base editing for splice correction of IVSI-110 ß-thalassemia.
Mol Ther Nucleic Acids
; 35(2): 102183, 2024 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38706633
8.
Short-hairpin RNA against aberrant HBBIVSI-110(G>A) mRNA restores ß-globin levels in a novel cell model and acts as mono- and combination therapy for ß-thalassemia in primary hematopoietic stem cells.
Haematologica
; 103(9): e419-e423, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29700171
9.
High-efficiency editing in hematopoietic stem cells and the HUDEP-2 cell line based on in vitro mRNA synthesis.
Front Genome Ed
; 5: 1141618, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36969374
10.
Evaluation of Mono- and Bi-Functional GLOBE-Based Vectors for Therapy of ß-Thalassemia by HBBAS3 Gene Addition and Mutation-Specific RNA Interference.
Cells
; 12(24)2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38132168
11.
Proteomic Studies for the Investigation of γ-Globin Induction by Decitabine in Human Primary Erythroid Progenitor Cultures.
J Clin Med
; 9(1)2020 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31947809
12.
Hb Famagusta--analysis of a novel δ-globin chain variant [HBD:c.60C>A] in four families with diverse globin genotypes.
Ann Hematol
; 93(9): 1625-7, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24452365
13.
The Scope for Thalassemia Gene Therapy by Disruption of Aberrant Regulatory Elements.
J Clin Med
; 8(11)2019 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31766235
14.
Rapid and Sensitive Assessment of Globin Chains for Gene and Cell Therapy of Hemoglobinopathies.
Hum Gene Ther Methods
; 29(1): 60-74, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29325430
15.
Hb A2 Episkopi - a novel δ-globin chain variant [HBD:c.428C>T] in a family of mixed Cypriot-Lebanese descent.
Hematology
; 22(5): 304-309, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28007020
16.
Survival of medically treated thalassemia patients in Cyprus. Trends and risk factors over the period 1980-2004.
Haematologica
; 91(9): 1187-92, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16956817
17.
The molecular spectrum and distribution of haemoglobinopathies in Cyprus: a 20-year retrospective study.
Sci Rep
; 6: 26371, 2016 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27199182
18.
Improved survival in thalassemia major patients on switching from desferrioxamine to combined chelation therapy with desferrioxamine and deferiprone.
Haematologica
; 94(12): 1777-8, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19815834
19.
Update on fertility in thalassaemia major.
Pediatr Endocrinol Rev
; 2 Suppl 2: 296-302, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16462715