Detalhe da pesquisa
1.
A multimodal atlas of hepatocellular carcinoma reveals convergent evolutionary paths and 'bad apple' effect on clinical trajectory.
J Hepatol
; 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38782118
2.
Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities.
Gut
; 72(2): 226-241, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35817555
3.
Comprehensive molecular phenotyping of ARID1A-deficient gastric cancer reveals pervasive epigenomic reprogramming and therapeutic opportunities.
Gut
; 72(9): 1651-1663, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36918265
4.
Epigenetic promoter alterations in GI tumour immune-editing and resistance to immune checkpoint inhibition.
Gut
; 71(7): 1277-1288, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34433583
5.
A phase 1b study of OXIRI in pancreatic adenocarcinoma patients and its immunomodulatory effects.
Int J Cancer
; 151(3): 435-449, 2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35415893
6.
Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations.
Blood
; 129(24): 3264-3268, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28408461
7.
PUREE: accurate pan-cancer tumor purity estimation from gene expression data.
Commun Biol
; 6(1): 394, 2023 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37041233
8.
A pan-cancer metabolic atlas of the tumor microenvironment.
Cell Rep
; 39(6): 110800, 2022 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35545044
9.
Accurate somatic variant detection using weakly supervised deep learning.
Nat Commun
; 13(1): 4248, 2022 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35869060
10.
Obtaining spatially resolved tumor purity maps using deep multiple instance learning in a pan-cancer study.
Patterns (N Y)
; 3(2): 100399, 2022 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35199060
11.
Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer.
Nat Genet
; 54(7): 963-975, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35773407
12.
Dynamic phenotypic heterogeneity and the evolution of multiple RNA subtypes in hepatocellular carcinoma: the PLANET study.
Natl Sci Rev
; 9(3): nwab192, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35382356
13.
Individualized Molecular Profiling for Allocation to Clinical Trials Singapore Study-An Asian Tertiary Cancer Center Experience.
JCO Precis Oncol
; 52021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34250396
14.
Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer.
Genome Med
; 13(1): 158, 2021 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34635154
15.
MutSpot: detection of non-coding mutation hotspots in cancer genomes.
NPJ Genom Med
; 5: 26, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32550006
16.
Ensemble-Based Somatic Mutation Calling in Cancer Genomes.
Methods Mol Biol
; 2120: 37-46, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32124310
17.
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer.
J Clin Invest
; 130(6): 3005-3020, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32364535
18.
Genomic landscape of lung adenocarcinoma in East Asians.
Nat Genet
; 52(2): 177-186, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32015526
19.
Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesis.
Nat Commun
; 10(1): 3682, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31417090
20.
Advances in genomic hepatocellular carcinoma research.
Gigascience
; 7(11)2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30521023