Detalhe da pesquisa
1.
Africa-specific human genetic variation near CHD1L associates with HIV-1 load.
Nature
; 620(7976): 1025-1030, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37532928
2.
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes.
Cell
; 154(2): 452-64, 2013 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23870131
3.
Author Correction: Africa-specific human genetic variation near CHD1L associates with HIV-1 load.
Nature
; 621(7979): E42, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37670157
4.
Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic Variant.
J Neurosci
; 41(49): 10194-10208, 2021 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34716231
5.
Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells.
Development
; 144(4): 635-648, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096221
6.
One-step generation of conditional and reversible gene knockouts.
Nat Methods
; 14(3): 287-289, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28135257
7.
Improving homology-directed repair efficiency in human stem cells.
Methods
; 164-165: 18-28, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31216442
8.
An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers.
Nucleic Acids Res
; 45(21): e174, 2017 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28981838
9.
Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform.
Biochim Biophys Acta
; 1863(7 Pt B): 1728-48, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26524115
10.
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects.
Nat Methods
; 11(4): 399-402, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24584192
11.
A conditional knockout resource for the genome-wide study of mouse gene function.
Nature
; 474(7351): 337-42, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21677750
12.
Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo".
Nat Methods
; 15(4): 235-236, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29600991
13.
WGE: a CRISPR database for genome engineering.
Bioinformatics
; 31(18): 3078-80, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25979474
14.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic Acids Res
; 42(Database issue): D802-9, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24194600
15.
Large structural variants in KOLF2.1J are unlikely to compromise neurological disease modelling.
bioRxiv
; 2024 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38352495
16.
Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia.
Nat Commun
; 15(1): 2497, 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38509062
17.
Molecular characterization of mutant mouse strains generated from the EUCOMM/KOMP-CSD ES cell resource.
Mamm Genome
; 24(7-8): 286-94, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23912999
18.
Dual RMCE for efficient re-engineering of mouse mutant alleles.
Nat Methods
; 7(11): 893-5, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20953177
19.
Off-target mutations are rare in Cas9-modified mice.
Nat Methods
; 12(6): 479, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26020497
20.
Floxin, a resource for genetically engineering mouse ESCs.
Nat Methods
; 7(1): 50-2, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19966808