Detalhe da pesquisa
1.
ß-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors.
Cell
; 181(6): 1364-1379.e14, 2020 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32470395
2.
Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator.
Biochemistry
; 62(7): 1233-1248, 2023 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36917754
3.
Prenatal heroin exposure alters brain morphology and connectivity in adolescent mice.
NMR Biomed
; 36(2): e4842, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36259728
4.
Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires ßarrestin-2.
Synapse
; 72(1)2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28941296
5.
ß-arrestin-biased Allosteric Modulator of Neurotensin Receptor 1 Reduces Ethanol Drinking and Responses to Ethanol Administration in Rodents.
bioRxiv
; 2024 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38645173
6.
Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism.
Mol Pharmacol
; 84(5): 774-86, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24019224
7.
Neurotensin receptor 1-biased ligand attenuates neurotensin-mediated excitation of ventral tegmental area dopamine neurons and dopamine release in the nucleus accumbens.
Neuropharmacology
; 234: 109544, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37055008
8.
Establishment of multi-stage intravenous self-administration paradigms in mice.
Sci Rep
; 12(1): 21422, 2022 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36503898
9.
Biased Allosteric Modulators: New Frontiers in GPCR Drug Discovery.
Trends Pharmacol Sci
; 42(4): 283-299, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33581873
10.
Editorial: GPCRs: signal transduction.
Front Mol Biosci
; 11: 1403161, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38660374
11.
Encoding the ß-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs.
ACS Pharmacol Transl Sci
; 2(4): 230-246, 2019 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32259059
12.
Discovery of ß-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators.
J Med Chem
; 62(17): 8357-8363, 2019 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31390201
13.
Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation.
Pain
; 158(9): 1733-1742, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28570482
14.
Angiotensin-(1-7)/Mas receptor as an antinociceptive agent in cancer-induced bone pain.
Pain
; 157(12): 2709-2721, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27541850
15.
The cystine/glutamate antiporter system xc- drives breast tumor cell glutamate release and cancer-induced bone pain.
Pain
; 157(11): 2605-2616, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27482630
16.
Therapeutic potential of peroxynitrite decomposition catalysts: a patent review.
Expert Opin Ther Pat
; 25(4): 443-66, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25576197
17.
Use of Animal Models in Understanding Cancer-induced Bone Pain.
Cancer Growth Metastasis
; 8(Suppl 1): 47-62, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26339191
18.
Transporters at CNS barrier sites: obstacles or opportunities for drug delivery?
Curr Pharm Des
; 20(10): 1422-49, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-23789948
19.
Hypoxia/reoxygenation stress signals an increase in organic anion transporting polypeptide 1a4 (Oatp1a4) at the blood-brain barrier: relevance to CNS drug delivery.
J Cereb Blood Flow Metab
; 34(4): 699-707, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24473481
20.
P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenac.
PLoS One
; 9(2): e88516, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24520393