Detalhe da pesquisa
1.
Heterogeneity in the progression of retinal pathologies in mice harboring patient mimicking Impg2 mutations.
Hum Mol Genet
; 33(5): 448-464, 2024 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37975905
2.
A Novel Triple-Action Inhibitor Targeting B-Cell Receptor Signaling and BRD4 Demonstrates Preclinical Activity in Chronic Lymphocytic Leukemia.
Int J Mol Sci
; 23(12)2022 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35743155
3.
Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects.
Cancer Res Commun
; 4(5): 1328-1343, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38687198
4.
BET inhibition reforms the immune microenvironment and alleviates T cell dysfunction in chronic lymphocytic leukemia.
JCI Insight
; 9(10)2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38775157
5.
Combinatorial inhibition of BTK, PI3K-AKT and BRD4-MYC as a strategy for treatment of mantle cell lymphoma.
Mol Biomed
; 3(1): 2, 2022 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35031886
6.
Insect cell expression and purification of recombinant SARS-COV-2 spike proteins that demonstrate ACE2 binding.
Protein Sci
; 31(5): e4300, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35481636
7.
Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Structure
; 30(9): 1224-1232.e5, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35716662
8.
Bromodomain and Extraterminal Protein Inhibitor, Apabetalone (RVX-208), Reduces ACE2 Expression and Attenuates SARS-Cov-2 Infection In Vitro.
Biomedicines
; 9(4)2021 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33919584
9.
Preclinical activity of a novel multi-axis inhibitor in aggressive and indolent B-cell malignancies.
Leuk Lymphoma
; 64(14): 2333-2337, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37706519