Detalhe da pesquisa
1.
Nonclinical safety biomarkers of drug-induced vascular injury: current status and blueprint for the future.
Toxicol Pathol
; 42(4): 635-57, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24777748
2.
A comparison of mortality and cardiac biomarker response between three outbred stocks of Sprague Dawley rats treated with isoproterenol.
Toxicol Pathol
; 39(4): 576-88, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21467541
3.
Recommendations on risk-based strategies for detection and characterization of antibodies against biotechnology products.
J Immunol Methods
; 333(1-2): 1-9, 2008 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-18275969
4.
Effects of Dulaglutide on Thyroid C Cells and Serum Calcitonin in Male Monkeys.
Endocrinology
; 156(7): 2409-16, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25860028
5.
Chronic Toxicity and Carcinogenicity Studies of the Long-Acting GLP-1 Receptor Agonist Dulaglutide in Rodents.
Endocrinology
; 156(7): 2417-28, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25860029
6.
A predictive F344 rat immunotoxicology model: cellular parameters combined with humoral response to NP-CgammaG and KLH.
Toxicology
; 194(1-2): 129-45, 2003 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14636702
7.
LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys.
PLoS One
; 8(6): e65763, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23823755
8.
Summary of confirmation cut point discussions.
AAPS J
; 13(2): 227-9, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21380610
9.
Electrochemiluminescent immunoassay for rat skeletal troponin I (Tnni2) in serum.
J Pharmacol Toxicol Methods
; 61(1): 52-8, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-19788923
10.
Detection of antibodies against therapeutic proteins in the presence of residual therapeutic protein using a solid-phase extraction with acid dissociation (SPEAD) sample treatment prior to ELISA.
Regul Toxicol Pharmacol
; 49(3): 230-7, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17869396
11.
Preclinical immunogenicity testing for recombinant therapeutic proteins.
J Immunotoxicol
; 2(4): 203-10, 2005 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18958675