Detalhe da pesquisa
1.
A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene.
Cell
; 143(4): 628-38, 2010 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21074052
2.
Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.
PLoS Genet
; 15(6): e1008226, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31199789
3.
Reversion mutation of cDNA CA8-204 minigene construct produces a truncated functional peptide that regulates calcium release in vitro and produces profound analgesia in vivo.
Mamm Genome
; 31(9-12): 287-294, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33247772
4.
A functional substitution in the L-aromatic amino acid decarboxylase enzyme worsens somatic symptoms via a serotonergic pathway.
Ann Neurol
; 86(2): 168-180, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31177555
5.
Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice.
Gene Ther
; 25(4): 297-311, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29789638
6.
Genomics of Cardiovascular Measures of Autonomic Tone.
J Cardiovasc Pharmacol
; 71(3): 180-191, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29300220
7.
Evidence that Dry Eye Represents a Chronic Overlapping Pain Condition.
Mol Pain
; 13: 1744806917729306, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28814146
8.
Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice.
Mamm Genome
; 28(9-10): 407-415, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28547032
9.
Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans.
J Med Genet
; 52(11): 762-9, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26337638
10.
Whole-genome methylation profiling reveals regions associated with painful temporomandibular disorders and active recovery processes.
Pain
; 165(5): 1060-1073, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38015635
11.
Large candidate gene association study reveals genetic risk factors and therapeutic targets for fibromyalgia.
Arthritis Rheum
; 64(2): 584-93, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21905019
12.
Applying the Rapid OPPERA Algorithm to Predict Persistent Pain Outcomes Among a Cohort of Women Undergoing Breast Cancer Surgery.
J Pain
; 23(12): 2003-2012, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35963491
13.
Phenotypic profile clustering pragmatically identifies diagnostically and mechanistically informative subgroups of chronic pain patients.
Pain
; 162(5): 1528-1538, 2021 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33259458
14.
Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons.
Sleep
; 44(3)2021 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33034629
15.
Effect of catechol-O-methyltransferase polymorphism on response to propranolol therapy in chronic musculoskeletal pain: a randomized, double-blind, placebo-controlled, crossover pilot study.
Pharmacogenet Genomics
; 20(4): 239-48, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20216107
16.
A genetic polymorphism that is associated with mitochondrial energy metabolism increases risk of fibromyalgia.
Pain
; 161(12): 2860-2871, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32658146
17.
Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males.
Pain
; 160(3): 579-591, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30431558
18.
Impact of human CA8 on thermal antinociception in relation to morphine equivalence in mice.
Neuroreport
; 28(18): 1215-1220, 2017 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28902707
19.
Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes.
Cell Rep
; 19(9): 1940-1952, 2017 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28564610
20.
Epiregulin and EGFR interactions are involved in pain processing.
J Clin Invest
; 127(9): 3353-3366, 2017 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28783046