Detalhe da pesquisa
1.
Single nuclei RNA-seq reveals a medium spiny neuron glutamate excitotoxicity signature prior to the onset of neuronal death in an ovine Huntington's disease model.
Hum Mol Genet
; 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38776957
2.
ICARUS v3, a massively scalable web server for single-cell RNA-seq analysis of millions of cells.
Bioinformatics
; 40(4)2024 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38539041
3.
Challenges for gene editing in common variable immunodeficiency disorders: Current and future prospects.
Clin Immunol
; 258: 109854, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38013164
4.
A common regulatory haplotype doubles lactoferrin concentration in milk.
Genet Sel Evol
; 56(1): 22, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38549172
5.
ICARUS, an interactive web server for single cell RNA-seq analysis.
Nucleic Acids Res
; 50(W1): W427-W433, 2022 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35536286
6.
Soluble wild-type ACE2 molecules inhibit newer SARS-CoV-2 variants and are a potential antiviral strategy to mitigate disease severity in COVID-19.
Clin Exp Immunol
; 214(3): 289-295, 2023 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37565297
7.
Natural cryptic variation in epigenetic modulation of an embryonic gene regulatory network.
Proc Natl Acad Sci U S A
; 117(24): 13637-13646, 2020 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32482879
8.
From Pathogenesis to Therapeutics: A Review of 150 Years of Huntington's Disease Research.
Int J Mol Sci
; 24(16)2023 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37629202
9.
Novel PRMT7 mutation in a rare case of dysmorphism and intellectual disability.
J Hum Genet
; 67(1): 19-26, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34244600
10.
Screening for phenotypic outliers identifies an unusually low concentration of a ß-lactoglobulin B protein isoform in bovine milk caused by a synonymous SNP.
Genet Sel Evol
; 54(1): 22, 2022 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35296234
11.
The genomes of precision edited cloned calves show no evidence for off-target events or increased de novo mutagenesis.
BMC Genomics
; 22(1): 457, 2021 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34139989
12.
Widespread cis-regulation of RNA editing in a large mammal.
RNA
; 25(3): 319-335, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30530731
13.
Testes of DAZL null neonatal sheep lack prospermatogonia but maintain normal somatic cell morphology and marker expression.
Mol Reprod Dev
; 88(1): 3-14, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33251684
14.
A Review of the Current Mammalian Models of Alzheimer's Disease and Challenges That Need to Be Overcome.
Int J Mol Sci
; 22(23)2021 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884970
15.
A new mechanism for a familiar mutation - bovine DGAT1 K232A modulates gene expression through multi-junction exon splice enhancement.
BMC Genomics
; 21(1): 591, 2020 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32847516
16.
Inconsistencies in histone acetylation patterns among different HD model systems and HD post-mortem brains.
Neurobiol Dis
; 146: 105092, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32979507
17.
Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases.
Proc Natl Acad Sci U S A
; 114(52): E11293-E11302, 2017 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29229845
18.
Multiple QTL underlie milk phenotypes at the CSF2RB locus.
Genet Sel Evol
; 51(1): 3, 2019 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30678637
19.
Genome-wide association analysis reveals QTL and candidate mutations involved in white spotting in cattle.
Genet Sel Evol
; 51(1): 62, 2019 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31703548
20.
Evaluation of the performance of copy number variant prediction tools for the detection of deletions from whole genome sequencing data.
J Biomed Inform
; 94: 103174, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30965134