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1.
BMC Musculoskelet Disord ; 21(1): 227, 2020 Apr 13.
Artigo em Inglês | MEDLINE | ID: mdl-32284044

RESUMO

BACKGROUND: Low back pain (LBP) is a common health problem experienced after natural disasters. LBP is often concurrent with other musculoskeletal pain; however, the effects of preexisting musculoskeletal pain on the development of LBP are not clear. The purpose of this study was to elucidate the association of musculoskeletal pain in other body sites with new-onset LBP among survivors of the Great East Japan Earthquake (GEJE). METHODS: A longitudinal study was conducted with survivors of the GEJE. The survivors who did not have LBP at the 3 year time period after the GEJE were followed up 1 year later (n = 1782). Musculoskeletal pain, such as low back, hand and/or foot, knee, shoulder, and neck pain, were assessed with self-reported questionnaires. The outcome of interest was new-onset LBP, which was defined as LBP absent at 3 years but present at 4 years after the disaster. The main predictor was musculoskeletal pain in other body sites 3 years after the GEJE, which was categorized according to the number of pain sites (0, 1, ≥ 2). Multiple regression analyses were performed to calculate the odds ratio (OR) and 95% confidence interval (CI) for new-onset LBP due to musculoskeletal pain in other body sites. RESULTS: The incidence of new-onset LBP was 14.1% (251/1782). Musculoskeletal pain in other body sites was significantly associated with new-onset LBP. Including people without other musculoskeletal pain as a reference, the adjusted OR and 95% CI for new-onset LBP were 1.73 (1.16-2.57) for people with one musculoskeletal pain site and 3.20 (2.01-5.09) for people with ≥ 2 sites (p <  0.001). CONCLUSIONS: Preexisting musculoskeletal pain in other body sites was associated with new-onset LBP among survivors in the recovery period after the GEJE.


Assuntos
Desastres , Terremotos , Dor Lombar/epidemiologia , Dor Musculoesquelética/epidemiologia , Sobreviventes/estatística & dados numéricos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Incidência , Japão/epidemiologia , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Análise de Regressão , Autorrelato , Adulto Jovem
2.
BMC Musculoskelet Disord ; 21(1): 761, 2020 Nov 19.
Artigo em Inglês | MEDLINE | ID: mdl-33213419

RESUMO

BACKGROUND: Joint hemorrhage is caused by trauma, ligament reconstruction surgery, and bleeding disorders such as hemophilia. Recurrence of hemorrhage in the joint space induces hemosiderotic synovitis and oxidative stress, resulting in both articular cartilage degeneration and arthropathy. Joint immobilization is a common treatment option for articular fractures accompanied by joint hemorrhage. Although joint hemorrhage has negative effects on the articular cartilage, there is no consensus on whether a reduction in joint hemorrhage would effectively prevent articular cartilage degeneration. The purpose of this study was to investigate the effect of joint hemorrhage combined with joint immobilization on articular cartilage degeneration in a rat immobilized knee model. METHODS: The knee joints of adult male rats were immobilized at the flexion using an internal fixator from 3 days to 8 weeks. The rats were randomly divided into the following groups: immobilized blood injection (Im-B) and immobilized-normal saline injection (Im-NS) groups. The cartilage was evaluated in two areas (contact and non-contact areas). The cartilage was used to assess chondrocyte count, Modified Mankin score, and cartilage thickness. The total RNA was extracted from the cartilage in both areas, and the expression of metalloproteinase (MMP)-8, MMP-13, interleukin (IL)-1ß, and tumor necrosis factor (TNF)-α was measured by quantitative real-time polymerase chain reaction. RESULTS: The number of chondrocytes in the Im-B group significantly decreased in both areas, compared with that in the Im-NS group. Modified Mankin score from 4 to 8 weeks of the Im-B group was significantly higher than that of the Im-NS group only in the contact area. The expression of MMP-8 and MMP-13 from 2 to 4 weeks and TNF-α from 2 to 8 weeks significantly increased in the Im-B group compared with those in the Im-NS group, but there was no significant difference in IL-1ß expression. CONCLUSIONS: The results showed that joint hemorrhage exacerbated immobilization-induced articular cartilage degeneration. Drainage of a joint hemorrhage or avoidance of loading may help prevent cartilage degeneration during joint immobilization with a hemorrhage.


Assuntos
Doenças das Cartilagens , Cartilagem Articular , Animais , Condrócitos , Hemartrose/etiologia , Articulação do Joelho , Masculino , Ratos
3.
Tohoku J Exp Med ; 250(2): 79-85, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-32062615

RESUMO

Basketball is a major sport worldwide among different age groups that leads to a high frequency of injuries at multiple body sites. Upper and lower extremities and lower back are common pain sites in basketball players; however, there is little information about the relationship between upper or lower extremity pain and lower back pain. This study elucidated the associations between upper extremity (shoulder and elbow) pain and lower back pain (LBP) among young basketball players. We conducted a cross-sectional study using self-reported questionnaires mailed to 25,669 young athletes; the final study population comprised 590 basketball players, and their median age was 13 years (range: 6-15 years). The point prevalence rates of lower back, shoulder, elbow, and upper extremity pain among young basketball players were 12.9% (76/590), 4.6% (27/590), 2.7% (16/590), and 7.1% (42/590), respectively. Multivariate logistic regression analyses revealed that upper extremity pain was significantly associated with LBP (adjusted odds ratio [OR]: 7.86; 95% confidential interval [CI], 3.93-15.72). Shoulder pain was significantly associated with training per week (> 4 days) (adjusted OR: 4.15; 95% CI: 1.29-13.40) and LBP (adjusted OR: 13.77; 95% CI: 5.70-33.24). This study indicates that upper extremity and shoulder pain is associated with LBP among young basketball players. Assessing for lower back pain, as well as elbow and/or shoulder pain, may help prevent severe injuries in young basketball players. In conclusion, parents and coaches should be properly re-educated to help improve lower back, upper extremity, and shoulder pain among young basketball players.


Assuntos
Atletas , Basquetebol , Dor Lombar/complicações , Extremidade Superior/patologia , Adolescente , Criança , Estudos Transversais , Cotovelo/patologia , Feminino , Humanos , Japão/epidemiologia , Dor Lombar/epidemiologia , Masculino , Prevalência , Dor de Ombro/complicações , Dor de Ombro/epidemiologia
4.
Tohoku J Exp Med ; 251(4): 295-301, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32759555

RESUMO

Martial arts, such as judo, kendo, and karate, are popular worldwide, not only among adults but also among children and adolescents. Although low back pain (LBP) is considered to be a common problem in these sports, it has been scarcely studied, especially in young athletes. The purpose of this study was to elucidate the point prevalence of and factors related to LBP among school-aged athletes in judo, kendo, and karate. A cross-sectional study was conducted in school-aged athletes (age, 6-15 years; n = 896) using a self-reported questionnaire. Multiple logistic regression models were used to assess the factors related to LBP along with the odds ratio (OR) and 95% confidence interval (95% CI). Variables included in the analysis were sex, age, body mass index, team level, number of days and hours of training, frequency of participation in games, practice intensity, and lower extremity pain. The prevalence of LBP was 6.9% in judo, 4.7% in kendo, and 2.9% in karate. Older age was significantly associated with LBP in judo (adjusted OR, 2.12 [95% CI, 1.24-3.61]), kendo (1.77 [1.27-2.47]), and karate (2.22 [1.14-4.33]). Lower extremity pain was significantly associated with LBP in judo (6.56 [1.57-27.34]) and kendo (21.66 [6.96-67.41]). Coaches should understand the characteristics of LBP in each martial art to develop strategies to prevent LBP among school-aged martial arts athletes.


Assuntos
Atletas , Dor Lombar/epidemiologia , Artes Marciais , Instituições Acadêmicas , Adolescente , Criança , Feminino , Humanos , Japão/epidemiologia , Modelos Logísticos , Masculino , Prevalência
5.
Tohoku J Exp Med ; 251(1): 19-26, 2020 05.
Artigo em Inglês | MEDLINE | ID: mdl-32435007

RESUMO

Musculoskeletal pain is a major problem among survivors of natural disasters. Functional disabilities in older adults increase after disasters and can lead to musculoskeletal pain. However, the effects of poor physical function on musculoskeletal pain after natural disasters remain unclear. This study aimed to elucidate the association of poor physical function with new-onset musculoskeletal pain among older survivors after the Great East Japan Earthquake (GEJE). Survivors aged ≥ 65 years, 3 years after the GEJE, were assessed longitudinally for 1 year (n = 646). Musculoskeletal pain was assessed using a self-reported questionnaire, and new-onset musculoskeletal pain was defined as absence and presence of pain at 3 years and 4 years, respectively, after the disaster. Physical function at 3 years after the disaster was assessed using the Kihon Checklist physical function score, which consists of 5 yes/no questions, and poor physical function was defined as a score of ≥ 3/5. Multivariate logistic regression analyses were used to assess the association of poor physical function with new-onset musculoskeletal pain. The incidence of new-onset musculoskeletal pain was 22.4%. Participants with poor physical function had a significantly higher rate of new-onset musculoskeletal pain. Compared with high physical function, the adjusted odds ratio (95% confidence interval) for new-onset musculoskeletal pain was 2.25 (1.37-3.69) in poor physical function (P = 0.001). Preceding poor physical function was associated with new-onset musculoskeletal pain among older survivors after the GEJE. There is need to focus on the maintenance of physical function to prevent musculoskeletal pain after natural disasters.


Assuntos
Terremotos , Dor Musculoesquelética/epidemiologia , Resistência Física , Idoso , Idoso de 80 Anos ou mais , Avaliação da Deficiência , Feminino , Humanos , Incidência , Japão , Estudos Longitudinais , Masculino , Dor Musculoesquelética/fisiopatologia , Desastres Naturais , Inquéritos e Questionários , Sobreviventes
6.
J Shoulder Elbow Surg ; 29(1): 139-145, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31521523

RESUMO

BACKGROUND: Evidence is scarce concerning the relationship of physical dysfunction of the trunk and lower extremities with elbow and shoulder pain in young baseball players. This study aimed to examine the association of joint flexibility of the trunk and lower extremities and dynamic postural control with elbow and shoulder pain among elite young baseball players. METHODS: We analyzed baseball players (aged 9-12 years) who participated in the National Junior Sports Clubs Baseball Festival. Range of motion in external rotation and internal rotation (IR) of the hip, as well as the finger-to-floor distance and heel-to-buttock distance, was measured. The straight-leg-raise test was also conducted. Dynamic postural control was evaluated using the Star Excursion Balance Test. Multivariable logistic regression analyses were conducted to examine the association of physical function with the elbow or shoulder pain incidence. RESULTS: Of 210 players surveyed, 177 without elbow or shoulder pain were included in the analysis. Of the participants, 16 (9.0%) reported having elbow or shoulder pain during the tournament. Participants with the incidence of elbow or shoulder pain had a significant restriction in hip IR of the stride leg compared with those without pain (35.8° vs. 43.7°, P = .022). There were no significant associations of other joint flexibilities and the Star Excursion Balance Test with elbow or shoulder pain. CONCLUSION: Decreased hip IR range of motion of the stride leg was significantly associated with the elbow or shoulder pain incidence. Players, coaches, and clinicians should consider the physical function of the trunk and lower extremities for the prevention of elbow and shoulder pain.


Assuntos
Beisebol/lesões , Articulação do Quadril/fisiologia , Dor Musculoesquelética/epidemiologia , Rotação , Dor de Ombro/epidemiologia , Traumatismos em Atletas/epidemiologia , Estudos de Casos e Controles , Criança , Cotovelo , Humanos , Incidência , Masculino , Equilíbrio Postural , Amplitude de Movimento Articular
7.
J Shoulder Elbow Surg ; 29(9): 1884-1891, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32279986

RESUMO

BACKGROUND: The etiology of frozen shoulder (FS) remains uncertain. Advanced glycation end-products (AGEs) cause the cross-linking and stabilization of collagen and are increased in FS. The purpose of this study was to elucidate the pathogenesis of FS by evaluating the receptor of AGE (RAGE)-dependent pathways. METHODS: Tissue samples of the coracohumeral ligament (CHL) and anterior inferior glenohumeral ligament (IGHL) were collected from 33 patients with FS, with severe stiffness, and 25 with rotator cuff tears (RCTs) as controls. Gene expression levels of RAGE, high-mobility group box 1 (HMGB1), Toll-like receptor 2 (TLR2), TLR4, nuclear factor-kappa B (NF-kB), and cytokines were evaluated using a quantitative real-time polymerase chain reaction. The immunoreactivities of carboxymethyllysine (CML), pentosidine, and RAGE were also evaluated. CML and pentosidine were further evaluated using high-performance liquid chromatography. RESULTS: Gene expression levels of RAGE, HMGB1, TLR2, TLR4, and NF-kB were significantly greater in the CHLs and IGHLs from the FS group than in those from the RCT group. Immunoreactivities of RAGE and CML were stronger in the CHLs and IGHLs from the FS group than in those from the RCT group. Pentosidine was weakly immunostained in the CHLs and IGHLs from the FS group. CML using high-performance liquid chromatography was significantly greater in the CHLs and IGHLs from the FS group than in those from the RCT group. CONCLUSIONS: AGEs and HMGB1 might play important roles in the pathogenesis of FS by binding to RAGE and activating NF-kB signaling pathways. Suppression of these pathways could be a treatment option for FS.


Assuntos
Bursite/metabolismo , Ligamentos Articulares/metabolismo , NF-kappa B/metabolismo , Receptor para Produtos Finais de Glicação Avançada/metabolismo , Adulto , Idoso , Estudos de Casos e Controles , Feminino , Expressão Gênica , Proteína HMGB1/genética , Proteína HMGB1/metabolismo , Humanos , Imuno-Histoquímica , Masculino , Pessoa de Meia-Idade , NF-kappa B/genética , Reação em Cadeia da Polimerase em Tempo Real , Receptor para Produtos Finais de Glicação Avançada/genética , Estudos Retrospectivos , Transdução de Sinais , Receptor 2 Toll-Like/genética , Receptor 2 Toll-Like/metabolismo , Receptor 4 Toll-Like/genética , Receptor 4 Toll-Like/metabolismo
8.
BMC Geriatr ; 19(1): 274, 2019 10 17.
Artigo em Inglês | MEDLINE | ID: mdl-31623559

RESUMO

BACKGROUND: Functional disability is a significant problem after natural disasters. Musculoskeletal pain is reported to increase after disasters, which can cause functional disability among survivors. However, the effects of musculoskeletal pain on functional decline after natural disasters are unclear. The present study aimed to examine the association between musculoskeletal pain and new-onset poor physical function among elderly survivors after the Great East Japan Earthquake. METHODS: A longitudinal study was conducted on survivors aged ≥65 years at three and 4 years after the Great East Japan Earthquake. A total of 747 persons were included in this study. Physical function was assessed using the Kihon Checklist. New-onset poor physical function was defined as low physical function not present at 3 years but present at 4 years after the disaster. Knee, hand or foot, low back, shoulder, and neck pain was assessed using a self-reported questionnaire and was defined as musculoskeletal pain. Musculoskeletal pain at 3 years after the disaster was categorized according to the number of pain regions (0, 1, ≥ 2). Multiple logistic regression analyses were performed to calculate the odds ratio (OR) and 95% confidence interval (95% CI) for new-onset poor physical function due to musculoskeletal pain. RESULTS: The incidence of new-onset poor physical function was 14.9%. New-onset poor physical function was significantly associated with musculoskeletal pain. Compared with "0" musculoskeletal pain region, the adjusted ORs (95% CI) were 1.39 (0.75-2.58) and 2.69 (1.52-4.77) in "1" and "≥ 2" musculoskeletal pain regions, respectively (p for trend = 0.003). CONCLUSIONS: Musculoskeletal pain is associated with new-onset poor physical function among elderly survivors after the Great East Japan Earthquake. Monitoring musculoskeletal pain is important to prevent physical function decline after natural disasters.


Assuntos
Terremotos , Dor Musculoesquelética/diagnóstico , Dor Musculoesquelética/epidemiologia , Desastres Naturais , Sobreviventes , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Japão/epidemiologia , Estudos Longitudinais , Masculino , Dor Musculoesquelética/psicologia , Autorrelato , Inquéritos e Questionários , Sobreviventes/psicologia
9.
Tohoku J Exp Med ; 248(2): 107-113, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31231079

RESUMO

Verbal and physical abuse from coaches has negative effects on young athletes. Although the abuse can lead to the athletes' dropping out, no studies have reported on this topic. The purpose of this study was to elucidate the association between experience of verbal or physical abuse from coaches and loss of motivation for the present sport in young athletes. School-aged athletes (age range, 6-15 years, n = 6,791) were assessed using a self-reported questionnaire. Multivariate logistic regression models were used to assess the association between experience of verbal or physical abuse and loss of motivation for the present sport. Variables considered in the models were sex, age, body mass index, presence of bodily pain, team levels, number of training days per week, number of training hours per day on weekdays and weekends, and frequency of participation in games. The prevalence of loss of motivation for the present sport was 8.1%. Experience of verbal or physical abuse was significantly associated with loss of motivation for the present sport and the adjusted odds ratios (95% confidence intervals) were 1.93 (1.54-2.42, p < 0.001) for verbal abuse and 1.76 (1.27-2.42, p = 0.001) for physical abuse. Findings of this study suggest that experience of verbal or physical abuse from coaches is associated with loss of motivation for the present sport. Eradication of verbal and physical abuse from coaches is important for young athletes to continue sport participation.


Assuntos
Atletas/psicologia , Motivação , Esportes/psicologia , Adolescente , Criança , Maus-Tratos Infantis , Intervalos de Confiança , Estudos Transversais , Feminino , Humanos , Incidência , Japão , Masculino , Razão de Chances
10.
Tohoku J Exp Med ; 249(4): 249-254, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31839627

RESUMO

Verbal or physical abuse from coaches has negative effects on young athletes, and the parents of athletes also have an influence on the sports environment. It is therefore important to understand parents' attitudes towards abuse against their children from the coaches. This study aimed to elucidate the characteristics of parents who accept the infliction of verbal or physical abuse on their children from coaches of youth sports teams. A cross-sectional study using self-report questionnaires was conducted with parents of young athletes (n = 6,493). Multivariate logistic regression models were used to assess the factors associated with parents' acceptability of verbal or physical abuse against their children. The proportion of parents who were accepting of verbal or physical abuse was 21.5%. Acceptability of verbal or physical abuse was significantly associated with male (odds ratio: 1.67, 95% confidence interval: 1.43-1.95), younger age (1.24, 1.09-1.41), lower educational attainment (1.32, 1.17-1.50), smoking habits (1.42, 1.23-1.63), experience of playing on a team with high levels of competition during their junior or high school days (1.31, 1.15-1.50), and experience of verbal and physical abuse by their own former coaches (3.59, 3.03-4.26 and 1.17, 1.02-1.35). About 58% and 28% of parents had experienced verbal and physical abuse from their own former coaches, and parents who had experienced verbal abuse themselves were most likely to be accepting of verbal or physical abuse towards their children. Educating parents is considered to be important for preventing and eradicating abuse against young athletes.


Assuntos
Maus-Tratos Infantis/psicologia , Tutoria , Pais/psicologia , Esportes Juvenis , Adulto , Criança , Intervalos de Confiança , Feminino , Humanos , Masculino , Razão de Chances
11.
Knee Surg Sports Traumatol Arthrosc ; 27(3): 985-990, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30194468

RESUMO

PURPOSE: Considerable research has focused on shoulder and elbow injuries among baseball players; however, although lumbar spine and knee injuries are commonly experienced, they are less frequently studied. During common motions in baseball, such as throwing, hitting, and running, energy is transferred from the lower extremities through the lower back to the upper body. Lower extremity pain, as well as lower back pain (LBP), can disrupt the kinematic chain, and it is important to understand the association between lower extremity complaints and LBP. The purpose of this study was to elucidate the association between knee pain and LBP among young baseball players. METHODS: A cross-sectional study was conducted with young baseball players (aged 6-15 years, n = 1,609) using a self-reported questionnaire. Multivariate logistic regression models were used for analyses. Variables considered in the models were sex, age, body mass index, team levels, number of days of training per week, number of hours in practice per day on weekdays and weekend, frequency of participation in games, practice intensity, and player position. RESULTS: The point prevalence of LBP and knee pain was 8.4% and 13.1%, respectively. Knee pain was significantly associated with LBP. Using the absence of knee pain as a reference, the adjusted odds ratio (95% confidence interval) for LBP was 5.83 (3.93-8.65) (p < 0.001) in the presence of knee pain. CONCLUSIONS: Knee pain was associated with LBP among young baseball players. Clinicians should pay attention to knee complaints to prevent and treat LBP among young baseball players. LEVEL OF EVIDENCE: III.


Assuntos
Artralgia/epidemiologia , Beisebol , Articulação do Joelho/fisiopatologia , Dor Lombar/epidemiologia , Adolescente , Artralgia/fisiopatologia , Criança , Estudos Transversais , Feminino , Humanos , Japão/epidemiologia , Masculino , Prevalência , Inquéritos e Questionários
12.
J Orthop Sci ; 24(2): 361-367, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30497788

RESUMO

BACKGROUND: Because the relationship between coaches and athletes is unequal, verbal and physical abuse remains a common problem among sports coaches. We aimed to elucidate the characteristics of baseball coaches who verbally/physically abuse young baseball players. METHODS: A cross-sectional study was conducted on youth sports team coaches in Miyagi prefecture, Japan (n = 380), using a self-reported questionnaire. Multivariate logistic regression models were used for the analyses, evaluating the following variables: sex, age, educational level, smoking habits, years of coaching, level of baseball-playing experience, personal experience with verbal/physical abuse by former coaches, satisfaction with athletes' attitudes, number of athletes on the team, team competition level, awareness of the recommendations of the Japanese Society of Clinical Sports Medicine, limitations in the total pitch count, difficulty in coaching in other positions, number of games per year, and acceptance of former verbal/physical abuse. RESULTS: The prevalence of verbal/physical abuse toward young athletes was 74.5% (n = 283) and 6.6% (n = 25), respectively. Verbal abuse was significantly associated with personal experience of verbal abuse by former coaches (odds ratio [OR]: 2.00, 95% confidence interval [95% CI]: 1.04-3.85), and acceptance of verbal/physical abuse (OR: 2.61, 95% CI: 1.34-5.10). Physical abuse was significantly associated with greater than 10 years of coaching experience (OR: 7.16, 95% CI: 1.36-37.78), personal experience with physical abuse by former coaches (OR: 4.25, 95% CI: 1.23-14.70), and acceptance of verbal/physical abuse (OR: 3.85, 95% CI: 1.51-9.84). CONCLUSIONS: Coaches' experiences with verbal/physical abuse by former coaches negatively affected young athletes. Breaking this cycle is necessary to keep athletes active and interested in playing baseball. LEVEL OF EVIDENCE: Level III.


Assuntos
Atletas/psicologia , Beisebol/psicologia , Tutoria/ética , Abuso Físico/estatística & dados numéricos , Inquéritos e Questionários , Adolescente , Beisebol/fisiologia , Estudos Transversais , Feminino , Humanos , Incidência , Relações Interpessoais , Japão , Modelos Logísticos , Masculino , Tutoria/métodos , Análise Multivariada , Avaliação das Necessidades , Fatores de Risco , Autorrelato , Estresse Psicológico , Adulto Jovem
13.
Mol Pain ; 14: 1744806918757286, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29353540

RESUMO

Muscle pain is a common condition that relates to various pathologies. Muscle overuse induces muscle pain, and neutrophils are key players in pain production. Neutrophils also play a central role in chronic pain by secreting interleukin (IL)-18. The aim of this study was to investigate the involvement of neutrophils and IL-18 in a mouse model of muscle pain. The right hind leg muscles of BALB/c mice were stimulated electrically to induce excessive muscle contraction. The left hind leg muscles were not stimulated. The pressure pain threshold, number of neutrophils, and IL-18 levels were investigated. Furthermore, the effects of the IL-18-binding protein and Brilliant Blue G on pain were investigated. In stimulated muscles, pressure pain thresholds decreased, and neutrophil and IL-18 levels increased compared with that in non-stimulated muscles. The administration of IL-18-binding protein and Brilliant Blue G attenuated hyperalgesia caused by excessive muscle contraction. These results suggest that increased IL-18 secretion from larger numbers of neutrophils elicits mechanical hyperalgesia.


Assuntos
Interleucina-18/metabolismo , Mialgia/patologia , Mialgia/fisiopatologia , Neutrófilos/patologia , Nociceptividade , Animais , Contagem de Células , Modelos Animais de Doenças , Estimulação Elétrica , Hiperalgesia/patologia , Hiperalgesia/fisiopatologia , Peptídeos e Proteínas de Sinalização Intercelular/metabolismo , Interleucina-18/administração & dosagem , Masculino , Camundongos Endogâmicos BALB C , Contração Muscular/efeitos dos fármacos , Músculos/efeitos dos fármacos , Músculos/patologia , Músculos/fisiopatologia , Mialgia/metabolismo , Neutrófilos/efeitos dos fármacos , Neutrófilos/metabolismo , Nociceptividade/efeitos dos fármacos , Limiar da Dor , Pressão , Proteínas Recombinantes/administração & dosagem , Proteínas Recombinantes/farmacologia , Corantes de Rosanilina/farmacologia
14.
Tohoku J Exp Med ; 244(4): 297-304, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-29643277

RESUMO

Verbal or physical abuse from coaches has a negative impact on young athletes. To prevent abuse against young athletes, it is important to know the characteristics of abusive coaches. This study aimed to elucidate the characteristics of coaches who commit verbal or physical abuse in youth sports teams. A cross-sectional study was conducted with coaches of youth sport teams in Miyagi prefecture, Japan (n = 1,283), using a self-reported questionnaire (response rate was 24.0%). Multivariate logistic regression models were used for analyses. The prevalence of verbal and physical abuse towards young athletes was 64.7% (n = 830) and 6.2% (n = 79), respectively. Verbal abuse was significantly associated with lower educational attainment (odds ratio (OR): 1.32, 95% confidence interval (95% CI): 1.03-1.69), experiences of verbal abuse by own coaches (OR: 1.85, 95% CI: 1.37-2.50), acceptability for verbal or physical abuse (OR: 2.53, 95% CI: 1.82-3.52), and dissatisfaction with athletes' attitude (OR: 1.62, 95% CI: 1.26-2.07). Physical abuse was significantly associated with experiences of physical abuse by respondents' coaches (OR: 2.71, 95% CI: 1.50-4.92), acceptability for verbal or physical abuse (OR: 3.89, 95% CI: 2.39-6.33), and longer experience of coaching in years (OR: 2.45, 95% CI: 1.20-4.98). The results of this study show that coaches who commit verbal or physical abuse had typically experienced abuse from their former coaches, and adopted a similar style. Breaking the negative cycle of verbal and physical abuse is necessary to eliminate the abuse of young athletes.


Assuntos
Atletas , Atitude , Maus-Tratos Infantis/estatística & dados numéricos , Mentores , Esportes , Comportamento Verbal , Adolescente , Adulto , Criança , Estudos Transversais , Feminino , Humanos , Japão , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Prevalência , Inquéritos e Questionários
15.
Tohoku J Exp Med ; 244(1): 25-32, 2018 01.
Artigo em Inglês | MEDLINE | ID: mdl-29321383

RESUMO

Sleep disturbance is a common symptom after natural disasters. Although musculoskeletal pain also increases after natural disasters, its relation to sleep disturbance is not clear. The purpose of this study was to determine the influence of musculoskeletal pain on new-onset sleep disturbance among survivors after the Great East Japan Earthquake (GEJE). A prospective cohort study was conducted with the survivors of the GEJE at two and three years after the earthquake. New-onset sleep disturbance was defined as sleep disturbance absent at two years and present at three years after the earthquake. The sites of musculoskeletal pain included low back, shoulder, knee, and hand or foot. The number of musculoskeletal pain sites at two years after the earthquake was divided into three categories (0, 1, and 2 or more). Univariate and multivariate logistic regression models were used to calculate the odds ratio (OR) and 95% confidence interval (95%CI) for new-onset sleep disturbance according to the number of musculoskeletal pain sites. A total of 1,102 survivors were included in this study and 14.6% of the participants reported new-onset sleep disturbance. Using "0" as a reference, the adjusted ORs (95% CI) for new-onset sleep disturbance were 2.43 (1.55-3.80) in "1" and 2.96 (1.88-4.64) in "2 or more", respectively (P for trends < 0.001). In conclusion, this is the first study showing higher incidence of sleep disturbance among survivors with musculoskeletal pain after the GEJE. Care for musculoskeletal pain is important to prevent sleep disturbance after natural disasters.


Assuntos
Terremotos , Dor Musculoesquelética/complicações , Dor Musculoesquelética/epidemiologia , Transtornos do Sono-Vigília/complicações , Transtornos do Sono-Vigília/epidemiologia , Sobreviventes/estatística & dados numéricos , Idoso , Feminino , Humanos , Incidência , Japão/epidemiologia , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos
16.
Tohoku J Exp Med ; 246(1): 9-14, 2018 09.
Artigo em Inglês | MEDLINE | ID: mdl-30175723

RESUMO

Lower back pain (LBP) is a common health problem after natural disasters. Although some related factors have been reported, the effect of sleep disturbances on LBP is not clear. The purpose of this study was to elucidate the influence of sleep disturbances on LBP after the Great East Japan earthquake (GEJE). A panel study was conducted with the survivors of the GEJE (n = 2,295) at three and four years after the disaster using self-reported questionnaires. The changes in the presence of LBP during the two periods were assessed; LBP was characterized as either new onset or continuation of LBP. The participants' sleep conditions were assessed, and the changes in sleep disturbances during the two periods were classified into four groups: absence, new onset, improvement, and continuation. Multivariate logistic regression models were used to analyze the association of the changes in sleep disturbance with new onset and continuation of LBP. The rates of new onset and continuation of LBP were 14.1% and 55.1%, respectively. The changes in sleep disturbances were significantly associated with new-onset and continuing LBP. Using "absence" as a reference for the change of sleep disturbance, the adjusted ORs (95% CI) for new-onset LBP were 2.19 (1.42-3.38) in "new onset," 1.38 (0.83-2.30) in "improvement," and 2.17 (1.50-3.15) in "continuation," and those for continuing LBP were 1.42 (0.71-2.84) in "new onset," 0.98 (0.55-1.74) in "improvement," and 1.60 (1.01-2.51) in "continuation." Careful attention should be paid to sleep disturbances to prevent and improve LBP after natural disasters.


Assuntos
Dor Lombar/etiologia , Desastres Naturais , Transtornos do Sono-Vigília/complicações , Sobreviventes , Idoso , Feminino , Humanos , Japão , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade
17.
J Shoulder Elbow Surg ; 27(9): 1629-1635, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30054242

RESUMO

BACKGROUND: The effect of lifestyle factors on elbow or shoulder pain in young baseball players remains unclear. This study examined the association of game playing and television viewing with elbow or shoulder pain among elite young baseball players. METHODS: Study participants were young baseball players (age, 9-12 years) who participated in the National Junior Sports Clubs Baseball Festival in 2017. The national tournament invited 16 teams (totaling 210 players) selected based on the results of the regional qualifying tournaments. Self-reported questionnaires were mailed to all players before the tournament. Multiple logistic regression analyses were used to assess the association of video game playing and television viewing behavior with elbow or shoulder pain. RESULTS: Among the 210 players polled, 200 male players were included in the analysis. The prevalence of elbow or shoulder pain was 30.0%. Playing video games for ≥3 hours/day was significantly associated with elbow or shoulder pain vs. spending <1 hour/day playing video games (odds ratio, 5.59; 95% confidence interval, 1.44-21.64; P = .013). The amount of time spent watching television was not significantly associated with the prevalence of elbow or shoulder pain. CONCLUSIONS: Playing video games for ≥3 hours/day was associated with elbow or shoulder pain among elite young male baseball players. These findings highlight the effect of lifestyle on elbow and shoulder pain and should be taken into consideration by players, coaches, parents, and clinicians for the prevention of elbow and shoulder pain.


Assuntos
Artralgia/epidemiologia , Beisebol , Articulação do Cotovelo , Dor de Ombro/epidemiologia , Jogos de Vídeo/efeitos adversos , Criança , Humanos , Masculino , Televisão , Fatores de Tempo
18.
J Orthop Sci ; 23(2): 334-340, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29133217

RESUMO

BACKGROUND: The Great East Japan Earthquake (GEJE) and Tsunami devastated the northeastern coast of Japan on March 11, 2011. This study aimed to determine whether sociopsychological factors, such as sleep disturbance and psychological distress, influenced new-onset subjective knee pain in survivors during the post-disaster phase of the GEJE. METHODS: From November 2012 to February 2013 (2 years after the GEJE) and from November 2013 to February 2014 (3 years after the GEJE), survivors (≥18 years) completed self-reported questionnaires. A total of 1470 survivors responded to the questionnaires and were included in this study. New-onset subjective knee pain was defined as knee pain by encircled response absent at 2 years but present at 3 years after the GEJE. Two years after the GEJE, ≥10/24 points on the Kessler Psychological Distress Scale, and ≥6/24 points on the Athens Insomnia Scale defined the presence of psychological distress and sleep disturbance, respectively. Multiple logistic regression analysis was used to estimate the odds ratio (OR) and 95% confidence interval (CI) of the association between new-onset subjective knee pain and psychological distress or sleep disturbance. RESULTS: Among the participants, 10.9% (160/1470) reported experiencing new-onset subjective knee pain. Sleep disturbance was significantly associated with new-onset subjective knee pain (OR, 1.57, 95% CI, 1.08-2.29, P = 0.017); however, psychological distress was not (OR, 1.07, 95% CI, 0.65-1.78, P = 0.80). CONCLUSIONS: This is the first study to indicate an association between sleep disturbance and new-onset subjective knee pain among survivors of the GEJE. 247/300.


Assuntos
Artralgia/etiologia , Terremotos , Articulação do Joelho , Transtornos do Sono-Vigília/diagnóstico , Sobreviventes/psicologia , Adulto , Artralgia/epidemiologia , Artralgia/fisiopatologia , Estudos de Coortes , Intervalos de Confiança , Feminino , Humanos , Incidência , Japão/epidemiologia , Masculino , Pessoa de Meia-Idade , Razão de Chances , Estudos Prospectivos , Medição de Risco , Índice de Gravidade de Doença , Transtornos do Sono-Vigília/epidemiologia , Transtornos do Sono-Vigília/etiologia , Estresse Psicológico , Inquéritos e Questionários , Tsunamis
19.
Tohoku J Exp Med ; 242(3): 193-201, 2017 07.
Artigo em Inglês | MEDLINE | ID: mdl-28701635

RESUMO

The Great East Japan Earthquake (GEJE) and Tsunami devastated the northeastern coast of Japan on March 11, 2011. This study attempted to determine whether socio-psychological factors such as sleep disturbance and psychological distress influenced new-onset subjective shoulder pain in survivors, during the post disaster phase of the GEJE. From November 2012 to February 2013 (2 years after the GEJE) and November 2014 to January 2015 (4 years after the GEJE), survivors (18 years old or over) answered self-reported questionnaires. In total, 1,454 survivors responded to the questionnaires and were thus included in this study. New-onset subjective shoulder pain was defined as shoulder pain by encircled response absent at 2 years, and present at 4 years after the GEJE. Two years after the GEJE, ≥ 10/24 points on the Kessler Psychological Distress Scale-6, and ≥ 6/24 points on the Athens Insomnia Scale defined the presence of psychological distress and sleep disturbance, respectively. Multiple logistic regression analysis was used to estimate the odds ratio (OR) and 95% confidence interval (CI) of the association between new-onset subjective shoulder pain, and psychological distress or sleep disturbance. Amongst participants, 7.2% (105/1,454) reported new-onset subjective shoulder pain. Sleep disturbance was significantly associated with new-onset subjective shoulder pain (OR = 1.92, 95% CI = 1.24-2.98, P = 0.004); however, psychological distress was not (OR = 0.78, 95% CI = 0.42-1.42, P = 0.41). In conclusion, this is the first study indicating an association between sleep disturbance and new-onset subjective shoulder pain amongst the survivors of the GEJE.


Assuntos
Dor de Ombro/complicações , Transtornos do Sono-Vigília/complicações , Idoso , Terremotos , Feminino , Humanos , Japão , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Inquéritos e Questionários , Sobreviventes , Tsunamis
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