Detalhe da pesquisa
1.
GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain.
Proc Natl Acad Sci U S A
; 118(31)2021 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34330837
2.
Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition.
Virol J
; 14(1): 236, 2017 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29228983
3.
Influenza A virus protein PB1-F2 from different strains shows distinct structural signatures.
Biochim Biophys Acta
; 1834(2): 568-82, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23220419
4.
HIV-1 p6-Another viral interaction partner to the host cellular protein cyclophilin A.
Biochim Biophys Acta
; 1824(4): 667-78, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22342556
5.
Co-adjuvanting DDA/TDB liposomes with a TLR7 agonist allows for IgG2a/c class-switching in the absence of Th1 cells.
NPJ Vaccines
; 8(1): 189, 2023 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38135685
6.
Nuclear import of isoforms of the cytomegalovirus kinase pUL97 is mediated by differential activity of NLS1 and NLS2 both acting through classical importin-α binding.
J Gen Virol
; 93(Pt 8): 1756-1768, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22552943
7.
Exploring the NCS-382 Scaffold for CaMKIIα Modulation: Synthesis, Biochemical Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant Stabilizer of the CaMKIIα Hub Domain.
J Med Chem
; 65(22): 15066-15084, 2022 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346645
8.
Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery.
J Med Chem
; 65(21): 14481-14526, 2022 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36263945
9.
Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly.
Retrovirology
; 8: 11, 2011 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21324168
10.
The host-pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains.
BMC Struct Biol
; 11: 49, 2011 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22185200
11.
Identification of Novel Fragments Binding to the PDZ1-2 Domain of PSD-95.
ChemMedChem
; 16(6): 949-954, 2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33305877
12.
Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.
J Med Chem
; 64(8): 4623-4661, 2021 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33818106
13.
The dynamics of linear polyubiquitin.
Sci Adv
; 6(42)2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33055165
14.
A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity.
J Med Chem
; 62(17): 8028-8052, 2019 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31411465
15.
Author Correction: Co-adjuvanting DDA/TDB liposomes with a TLR7 agonist allows for IgG2a/c class-switching in the absence of Th1 cells.
NPJ Vaccines
; 9(1): 13, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38212391