Detalhe da pesquisa
1.
Discovery of a dual-action small molecule that improves neuropathological features of Alzheimer's disease mice.
Proc Natl Acad Sci U S A
; 119(3)2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35027452
2.
Gossypetin Prevents the Progression of Nonalcoholic Steatohepatitis by Regulating Oxidative Stress and AMP-Activated Protein Kinase.
Mol Pharmacol
; 104(5): 214-229, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37595967
3.
N,N'-Diacetyl-p-phenylenediamine restores microglial phagocytosis and improves cognitive defects in Alzheimer's disease transgenic mice.
Proc Natl Acad Sci U S A
; 116(47): 23426-23436, 2019 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31685616
4.
Factors determining the oral absorption and systemic disposition of zeaxanthin in rats: in vitro, in situ, and in vivo evaluations.
Pharm Biol
; 60(1): 2266-2275, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36412560
5.
A Glycosylated Prodrug to Attenuate Neuroinflammation and Improve Cognitive Deficits in Alzheimer's Disease Transgenic Mice.
Mol Pharm
; 18(1): 101-112, 2021 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33241681
6.
In vitro modulatory effects of ginsenoside compound K, 20(S)-protopanaxadiol and 20(S)-protopanaxatriol on uridine 5'-diphospho-glucuronosyltransferase activity and expression.
Xenobiotica
; 51(10): 1087-1094, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34338601
7.
Pharmacokinetics of α-amanitin in mice using liquid chromatography-high resolution mass spectrometry and in vitro drug-drug interaction potentials.
J Toxicol Environ Health A
; 84(20): 821-835, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34187333
8.
Ilimaquinone inhibits neovascular age-related macular degeneration through modulation of Wnt/ß-catenin and p53 pathways.
Pharmacol Res
; 161: 105146, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32814173
9.
Interactions between cyazofamid and human drug transporters.
J Biochem Mol Toxicol
; 34(4): e22459, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32003934
10.
Characterization of red ginseng-drug interaction by CYP3A activity increased in high dose administration in mice.
Biopharm Drug Dispos
; 41(7): 295-306, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32557706
11.
In Vitro Interaction of AB-FUBINACA with Human Cytochrome P450, UDP-Glucuronosyltransferase Enzymes and Drug Transporters.
Molecules
; 25(19)2020 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33050066
12.
Herb-Drug Interaction of Red Ginseng Extract and Ginsenoside Rc with Valsartan in Rats.
Molecules
; 25(3)2020 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32023909
13.
Ginsenoside Rc Is a New Selective UGT1A9 Inhibitor in Human Liver Microsomes and Recombinant Human UGT Isoforms.
Drug Metab Dispos
; 47(12): 1372-1379, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31578207
14.
Simultaneous Determination and Pharmacokinetic Characterization of Glycyrrhizin, Isoliquiritigenin, Liquiritigenin, and Liquiritin in Rat Plasma Following Oral Administration of Glycyrrhizae Radix Extract.
Molecules
; 24(9)2019 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31083444
15.
Detection of 13 Ginsenosides (Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg3, Rh2, F1, Compound K, 20(S)-Protopanaxadiol, and 20(S)-Protopanaxatriol) in Human Plasma and Application of the Analytical Method to Human Pharmacokinetic Studies Following Two Week-Repeated Administration of Red Ginseng Extract.
Molecules
; 24(14)2019 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31323835
16.
In Vitro Inhibitory Effects of APINACA on Human Major Cytochrome P450, UDP-Glucuronosyltransferase Enzymes, and Drug Transporters.
Molecules
; 24(16)2019 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31430908
17.
Physiologically Based Pharmacokinetic Modeling of Fimasartan, Amlodipine, and Hydrochlorothiazide for the Investigation of Drug-Drug Interaction Potentials.
Pharm Res
; 35(12): 236, 2018 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30324316
18.
Ursodeoxycholate Restores Biliary Excretion of Methotrexate in Rats with Ethinyl Estradiol Induced-Cholestasis by Restoring Canalicular Mrp2 Expression.
Int J Mol Sci
; 19(4)2018 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29642532
19.
Effects of Red Ginseng Extract on the Pharmacokinetics and Elimination of Methotrexate via Mrp2 Regulation.
Molecules
; 23(11)2018 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30424502
20.
Pharmacokinetics of Jaspine B and Enhancement of Intestinal Absorption of Jaspine B in the Presence of Bile Acid in Rats.
Mar Drugs
; 15(9)2017 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28862650