Detalhe da pesquisa
1.
Activation of Rictor/mTORC2 signaling acts as a pivotal strategy to protect against sensorineural hearing loss.
Proc Natl Acad Sci U S A
; 119(10): e2107357119, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35238644
2.
Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice.
Hum Mol Genet
; 31(20): 3504-3520, 2022 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35666215
3.
EGR1 and EGR2 positively regulate plant ABA signaling by modulating the phosphorylation of SnRK2.2.
New Phytol
; 241(4): 1492-1509, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38095247
4.
YIPF5 (p.W218R) mutation induced primary microcephaly in rabbits.
Neurobiol Dis
; 182: 106135, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37142085
5.
Multifunctional agents against Alzheimer's disease based on oxidative stress: Polysubstituted pyrazine derivatives synthesized by multicomponent reactions.
Bioorg Med Chem
; 96: 117535, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37956505
6.
Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategies.
Bioorg Chem
; 134: 106465, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36933339
7.
Versatile and efficient in vivo genome editing with compact Streptococcus pasteurianus Cas9.
Mol Ther
; 30(1): 256-267, 2022 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34174445
8.
CRISPR/Cas9-mediated deletion of Fam83h induces defective tooth mineralization and hair development in rabbits.
J Cell Mol Med
; 26(22): 5670-5679, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36300761
9.
Highly efficient base editing with expanded targeting scope using SpCas9-NG in rabbits.
FASEB J
; 34(1): 588-596, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914687
10.
Discovery of potent and selective Cdc25 phosphatase inhibitors via rapid assembly and in situ screening of Quinonoid-focused libraries.
Bioorg Chem
; 115: 105254, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34426152
11.
Genetic deletion of a short fragment of glucokinase in rabbit by CRISPR/Cas9 leading to hyperglycemia and other typical features seen in MODY-2.
Cell Mol Life Sci
; 77(16): 3265-3277, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31720743
12.
Precise base editing with CC context-specificity using engineered human APOBEC3G-nCas9 fusions.
BMC Biol
; 18(1): 111, 2020 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32867757
13.
The disrupted balance between hair follicles and sebaceous glands in Hoxc13-ablated rabbits.
FASEB J
; 33(1): 1226-1234, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30125135
14.
The minimal promoter (P1) of Xist is non-essential for X chromosome inactivation.
RNA Biol
; 17(5): 623-629, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32036747
15.
Expanded targeting scope and enhanced base editing efficiency in rabbit using optimized xCas9(3.7).
Cell Mol Life Sci
; 76(20): 4155-4164, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31030226
16.
Bioinformatics Analysis Identifies the Estrogen Receptor 1 (ESR1) Gene and hsa-miR-26a-5p as Potential Prognostic Biomarkers in Patients with Intrahepatic Cholangiocarcinoma.
Med Sci Monit
; 26: e921815, 2020 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32435051
17.
Molecular design opportunities presented by solvent-exposed regions of target proteins.
Med Res Rev
; 39(6): 2194-2238, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31002405
18.
Efficient dual sgRNA-directed large gene deletion in rabbit with CRISPR/Cas9 system.
Cell Mol Life Sci
; 73(15): 2959-68, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26817461
19.
DNA methylation modulates H19 and IGF2 expression in porcine female eye.
Genet Mol Biol
; 40(1): 153-159, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28266684
20.
D-repeat in the XIST gene is required for X chromosome inactivation.
RNA Biol
; 13(2): 172-6, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26786668