Detalhe da pesquisa
1.
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds.
J Med Chem
; 67(8): 6456-6494, 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38574366
2.
Identification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal site.
Sci Rep
; 12(1): 14561, 2022 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36028520
3.
Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with in Vivo Efficacy and Analysis of their Binding Mode Based on X-ray Cocrystal Structures.
J Med Chem
; 60(12): 4840-4860, 2017 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28537728
4.
Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis.
ACS Infect Dis
; 3(1): 18-33, 2017 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27704782