Detalhe da pesquisa
1.
Human Genetic Determinants of Viral Diseases.
Annu Rev Genet
; 51: 241-263, 2017 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28853921
2.
Human lysyl-tRNA synthetase phosphorylation promotes HIV-1 proviral DNA transcription.
Nucleic Acids Res
; 51(22): 12111-12123, 2023 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37933844
3.
TRAF6 and TAK1 Contribute to SAMHD1-Mediated Negative Regulation of NF-κB Signaling.
J Virol
; 95(3)2021 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33177202
4.
The dNTPase activity of SAMHD1 is important for its suppression of innate immune responses in differentiated monocytic cells.
J Biol Chem
; 295(6): 1575-1586, 2020 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914403
5.
SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways.
Proc Natl Acad Sci U S A
; 115(16): E3798-E3807, 2018 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29610295
6.
N6-Methyladenosine-binding proteins suppress HIV-1 infectivity and viral production.
J Biol Chem
; 293(34): 12992-13005, 2018 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29976753
7.
A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation.
J Virol
; 92(6)2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29321329
8.
SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4+ T Cells.
J Virol
; 92(15)2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29793958
9.
HIV-1 Exploits a Dynamic Multi-aminoacyl-tRNA Synthetase Complex To Enhance Viral Replication.
J Virol
; 91(21)2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28814526
10.
A Putative Cyclin-binding Motif in Human SAMHD1 Contributes to Protein Phosphorylation, Localization, and Stability.
J Biol Chem
; 291(51): 26332-26342, 2016 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27815502
11.
Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1.
J Virol
; 88(10): 5834-44, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24623419
12.
SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons.
Retrovirology
; 9: 105, 2012 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23231760
13.
SAMHD1: a new insight into HIV-1 restriction in myeloid cells.
Retrovirology
; 8: 55, 2011 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21740548
14.
SAMHD1 Suppression of Antiviral Immune Responses.
Trends Microbiol
; 27(3): 254-267, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30336972
15.
The Dynamic Interplay between HIV-1, SAMHD1, and the Innate Antiviral Response.
Front Immunol
; 8: 1541, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29176984
16.
Phosphorylation of mouse SAMHD1 regulates its restriction of human immunodeficiency virus type 1 infection, but not murine leukemia virus infection.
Virology
; 487: 273-84, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26580513
17.
SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells.
Virology
; 495: 92-100, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27183329
18.
Non-POU Domain-Containing Octamer-Binding Protein Negatively Regulates HIV-1 Infection in CD4(+) T Cells.
AIDS Res Hum Retroviruses
; 31(8): 806-16, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25769457
19.
HIV-1 Nef enhances dendritic cell-mediated viral transmission to CD4+ T cells and promotes T-cell activation.
PLoS One
; 7(3): e34521, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22479639
20.
SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity.
Nat Med
; 22(10): 1072-1074, 2016 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27711056