Detalhe da pesquisa
1.
A novel gain-of-function phosphorylation site modulates PTPN22 inhibition of TCR signaling.
J Biol Chem
; : 107393, 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38777143
2.
T-helper cell regulation of CD45 phosphatase activity by galectin-1 and CD43 governs chronic lymphocytic leukaemia proliferation.
Br J Haematol
; 198(3): 556-573, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35655388
3.
The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity.
Immunity
; 39(1): 111-22, 2013 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23871208
4.
RPTPα phosphatase activity is allosterically regulated by the membrane-distal catalytic domain.
J Biol Chem
; 295(15): 4923-4936, 2020 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32139509
5.
The low molecular weight protein tyrosine phosphatase promotes adipogenesis and subcutaneous adipocyte hypertrophy.
J Cell Physiol
; 236(9): 6630-6642, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33615467
6.
PTPN14 phosphatase and YAP promote TGFß signalling in rheumatoid synoviocytes.
Ann Rheum Dis
; 78(5): 600-609, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30808624
7.
Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat Chem Biol
; 13(6): 624-632, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28346406
8.
Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice.
J Immunol
; 195(10): 4841-52, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26438525
9.
T-helper signals restore B-cell receptor signaling in autoreactive anergic B cells by upregulating CD45 phosphatase activity.
J Allergy Clin Immunol
; 138(3): 839-851.e8, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27056269
10.
TGFß responsive tyrosine phosphatase promotes rheumatoid synovial fibroblast invasiveness.
Ann Rheum Dis
; 75(1): 295-302, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25378349
11.
Deletion of low molecular weight protein tyrosine phosphatase (Acp1) protects against stress-induced cardiomyopathy.
J Pathol
; 237(4): 482-94, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26213100
12.
pCAP-based peptide substrates: the new tool in the box of tyrosine phosphatase assays.
Methods
; 65(2): 165-74, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23886911
13.
High-throughput screen using a single-cell tyrosine phosphatase assay reveals biologically active inhibitors of tyrosine phosphatase CD45.
Proc Natl Acad Sci U S A
; 109(35): 13972-7, 2012 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22891353
14.
Protein tyrosine phosphatase expression profile of rheumatoid arthritis fibroblast-like synoviocytes: a novel role of SH2 domain-containing phosphatase 2 as a modulator of invasion and survival.
Arthritis Rheum
; 65(5): 1171-80, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23335101
15.
PTPN22 alters the development of regulatory T cells in the thymus.
J Immunol
; 188(11): 5267-75, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22539785
16.
Laser Capture Microscopy RNA Sequencing for Topological Mapping of Synovial Pathology During Rheumatoid Arthritis.
Arthritis Rheumatol
; 2024 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38556917
17.
Targeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy.
Sci Adv
; 10(5): eadg7887, 2024 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38295166
18.
Substrate selection influences molecular recognition in a screen for lymphoid tyrosine phosphatase inhibitors.
Chembiochem
; 14(13): 1640-7, 2013 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23956195
19.
Targeting protein phosphatases in cancer immunotherapy and autoimmune disorders.
Nat Rev Drug Discov
; 22(4): 273-294, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36693907
20.
Regulation of TCR signalling by tyrosine phosphatases: from immune homeostasis to autoimmunity.
Immunology
; 137(1): 1-19, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22862552