Detalhe da pesquisa
1.
Engineered IL13 variants direct specificity of IL13Rα2-targeted CAR T cell therapy.
Proc Natl Acad Sci U S A
; 119(33): e2112006119, 2022 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35939683
2.
Massively-Parallelized, Deterministic Mechanoporation for Intracellular Delivery.
Nano Lett
; 20(2): 860-867, 2020 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31647675
3.
Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy.
N Engl J Med
; 375(26): 2561-9, 2016 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28029927
4.
Optimization of IL13Rα2-Targeted Chimeric Antigen Receptor T Cells for Improved Anti-tumor Efficacy against Glioblastoma.
Mol Ther
; 26(1): 31-44, 2018 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29103912
5.
Chimeric antigen receptors with mutated IgG4 Fc spacer avoid fc receptor binding and improve T cell persistence and antitumor efficacy.
Mol Ther
; 23(4): 757-68, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25366031
6.
T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia.
Blood
; 122(18): 3138-48, 2013 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-24030378
7.
Targeting Wnt signaling for improved glioma immunotherapy.
Front Immunol
; 15: 1342625, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38449858
8.
Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial.
Nat Med
; 30(4): 1001-1012, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38454126
9.
Inclusion of 4-1BB Costimulation Enhances Selectivity and Functionality of IL13Rα2-Targeted Chimeric Antigen Receptor T Cells.
Cancer Res Commun
; 3(1): 66-79, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36968221
10.
Spatial organization of heterogeneous immunotherapy target antigen expression in high-grade glioma.
Neoplasia
; 30: 100801, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35550513
11.
Antibody-based redirection of universal Fabrack-CAR T cells selectively kill antigen bearing tumor cells.
J Immunother Cancer
; 10(6)2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35728874
12.
3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells.
Cell Stem Cell
; 29(4): 515-527.e8, 2022 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35278370
13.
Off-the-shelf, steroid-resistant, IL13Rα2-specific CAR T cells for treatment of glioblastoma.
Neuro Oncol
; 24(8): 1318-1330, 2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35100373
14.
IFNγ Is Critical for CAR T Cell-Mediated Myeloid Activation and Induction of Endogenous Immunity.
Cancer Discov
; 11(9): 2248-2265, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33837065
15.
CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies.
Cancer Discov
; 11(5): 1192-1211, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33328215
16.
Systemic Anti-PD-1 Immunotherapy Results in PD-1 Blockade on T Cells in the Cerebrospinal Fluid.
JAMA Oncol
; 6(12): 1947-1951, 2020 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33030521
17.
Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma.
Sci Transl Med
; 12(533)2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32132216
18.
In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function.
J Vis Exp
; (144)2019 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30882787
19.
IL15 Enhances CAR-T Cell Antitumor Activity by Reducing mTORC1 Activity and Preserving Their Stem Cell Memory Phenotype.
Cancer Immunol Res
; 7(5): 759-772, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890531
20.
Author Correction: Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial.
Nat Med
; 30(5): 1501, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38514871