1.
Bioorg Med Chem Lett
; 26(15): 3514-7, 2016 08 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27344207
RESUMO
We designed and prepared synthetic phospholipids that generate lyso-phosphatidylcholine products with a unique mass for convenient detection by LC-MS in complex biological matrices. We demonstrated that compound 4, formulated either as a Triton X-100 emulsion or incorporated in synthetic HDL particles can serve as a substrate for plasma EL with useful specificity.