Analysis of Social Media Posts That Promote Women Surgeons.

OBJECTIVE: The purpose of this study was to analyze the content, interaction, and use of posts related to women surgeons on Instagram and Twitter, with specific analysis of female orthopedic surgeon related content. DESIGN: A retrospective search of Instagram and Twitter from March 14, 2022, to June 16, 2022 was conducted using the hashtags, #womeninortho, #womeninorthopedics, #ilooklikeasurgeon, #womensurgeons, and #womeninsurgery. Additional searches were performed on Twitter that consisted of #orthotwitter in combination with #ilooklikeasurgeon, #womensurgeons, and #womeninsurgery. Once identified, posts were analyzed for the hashtag used, number of likes, number of comments, number of retweets (Twitter only), source type, type of post, and medical specialty. Descriptive statistics were used to analyze the data. RESULTS: Over the 3-month period, a total of 3248 posts were identified that included 1669 Instagram (50.5%) and 1639 Twitter (49.6%) posts. The majority of overall posts and Instagram posts were made by general (32.3%, 28.9%), plastic (12.7%, 22.1%), and orthopedic surgeons (8.3%, 7.8%). On Twitter, general surgeons tweeted the most (35.6%), followed by orthopaedic surgeons (8.8%). Instagram had a greater mean number of and comments per post than Twitter. For orthopedic hashtags, #womeninortho was used more than #womeninorthopedics (78.0% vs. 22.0%, p < 0.001). On #orthotwitter, #ilooklikeasurgeon was used more than #womeninsurgery and #womensurgeons (75.0% vs. 23.6% vs. 1.4%, p < 0.001). CONCLUSIONS: This study demonstrated that both Instagram and Twitter are regularly used to promote women surgeons. Instagram is the preferred platform of physicians for promoting women surgeons via personal and outcome-based content, while Twitter is used more by students and primarily includes outcome-based posts. Female orthopedic surgeons should continue to use the preferred hashtag, #womeninortho, to maximize the reach of this content. By promoting women surgeons on social media, practicing surgeons can converse, collaborate, and provide mentorship to the next generation of surgeons.

Stress-induced glucocorticoid desensitizes adrenoreceptors to gate the neuroendocrine response to somatic stress in male mice.

Noradrenergic afferents to hypothalamic corticotropin releasing hormone (CRH) neurons provide a major excitatory drive to the hypothalamic-pituitary-adrenal (HPA) axis via α1 adrenoreceptor activation. Noradrenergic afferents are recruited preferentially by somatic, rather than psychological, stress stimuli. Stress-induced glucocorticoids feed back onto the hypothalamus to negatively regulate the HPA axis, providing a critical autoregulatory constraint that prevents glucocorticoid overexposure and neuropathology. Whether negative feedback mechanisms target stress modality-specific HPA activation is not known. Here, we describe a desensitization of the α1 adrenoreceptor activation of the HPA axis following acute stress in male mice that is mediated by rapid glucocorticoid regulation of adrenoreceptor trafficking in CRH neurons. Glucocorticoid-induced α1 receptor trafficking desensitizes the HPA axis to a somatic but not a psychological stressor. Our findings demonstrate a rapid glucocorticoid suppression of adrenergic signaling in CRH neurons that is specific to somatic stress activation, and they reveal a rapid, stress modality-selective glucocorticoid negative feedback mechanism.