Detalhe da pesquisa
1.
Quantitative Translational Analysis of Brain Kynurenic Acid Modulation via Irreversible Kynurenine Aminotransferase II Inhibition.
Mol Pharmacol
; 94(2): 823-833, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29853495
2.
Reduction of brain kynurenic acid improves cognitive function.
J Neurosci
; 34(32): 10592-602, 2014 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25100593
3.
Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice.
Drug Metab Dispos
; 40(11): 2067-73, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22837388
4.
Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: evidence for altered striatal function.
Neuropharmacology
; 51(2): 374-85, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16769090
5.
Immunohistochemical localization of phosphodiesterase 10A in multiple mammalian species.
J Histochem Cytochem
; 54(11): 1205-13, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16864896
6.
Immunohistochemical localization of PDE10A in the rat brain.
Brain Res
; 985(2): 113-26, 2003 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-12967715
7.
Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions.
ACS Med Chem Lett
; 4(1): 37-40, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900560
8.
Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia.
ACS Med Chem Lett
; 3(3): 187-92, 2012 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900455
9.
Modulation of NMDA receptor function by inhibition of D-amino acid oxidase in rodent brain.
Neuropharmacology
; 61(5-6): 1001-15, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21763704
10.
Alterations in gene regulation following inhibition of the striatum-enriched phosphodiesterase, PDE10A.
Neuropharmacology
; 58(2): 444-51, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19765598
11.
Discovery, SAR, and pharmacokinetics of a novel 3-hydroxyquinolin-2(1H)-one series of potent D-amino acid oxidase (DAAO) inhibitors.
J Med Chem
; 52(11): 3576-85, 2009 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19438227
12.
Phosphodiesterase 10A inhibitors as a novel therapeutic approach for schizophrenia.
Expert Opin Drug Discov
; 2(7): 1001-9, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23484819
13.
Expression of rat I-TAC/CXCL11/SCYA11 during central nervous system inflammation: comparison with other CXCR3 ligands.
Lab Invest
; 84(11): 1418-29, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15322564
14.
Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain.
Biochemistry
; 41(26): 8289-97, 2002 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12081477