Detalhe da pesquisa
1.
HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression.
Blood
; 139(18): 2797-2815, 2022 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35286385
2.
Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia.
Cancer Res
; 84(7): 1101-1114, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38285895
3.
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.
Nature
; 442(7104): 818-22, 2006 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16862118
4.
HOXA9 is required for survival in human MLL-rearranged acute leukemias.
Blood
; 113(11): 2375-85, 2009 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19056693
5.
A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms.
Cancer Discov
; 11(12): 3126-3141, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34193440
6.
BET Inhibition Enhances the Antileukemic Activity of Low-dose Venetoclax in Acute Myeloid Leukemia.
Clin Cancer Res
; 27(2): 598-607, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33148670
7.
Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia.
Gene
; 752: 144758, 2020 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32422235
8.
Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors.
Sci Transl Med
; 12(534)2020 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32161105
9.
The pan-PIM inhibitor INCB053914 displays potent synergy in combination with ruxolitinib in models of MPN.
Blood Adv
; 3(22): 3503-3514, 2019 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31725895
10.
The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies.
Clin Cancer Res
; 25(1): 300-311, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30206163
11.
Therapeutic implications of leukemia stem cell development.
Clin Cancer Res
; 13(12): 3439-42, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17575205
12.
Murine Retrovirally-Transduced Bone Marrow Engraftment Models of MLL-Fusion-Driven Acute Myelogenous Leukemias (AML).
Curr Protoc Pharmacol
; 78: 14.42.1-14.42.19, 2017 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28892146
13.
The amino-terminus of the E2F-1 transcription factor inhibits DNA replication of autonomously replicating plasmids in mammalian cells.
Oncogene
; 21(23): 3715-26, 2002 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-12032840
14.
Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL.
Clin Cancer Res
; 21(10): 2348-58, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25688158
15.
FLT3 as a therapeutic target in childhood acute leukemia.
Curr Drug Targets
; 8(6): 703-14, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17584026