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Int J Biol Macromol ; 273(Pt 1): 132954, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38852726

RESUMO

This study explores the potential of liposome encapsulated silica immobilized cytochrome P450 monooxygenase (LSICY) for bioremediation of mercury (Hg2+). Current limitations in Hg2+ reduction, including sensitivity to factors like pH and cost, necessitate alternative methods. We propose LSICY as a solution, leveraging the enzymatic activities of cytochrome P450 monooxygenase (CYPM) for Hg2+ reduction through hydroxylation and oxygenation. Our investigation employs LSICY to assess its efficacy in mitigating Hg2+ toxicity in Oryza sativa (rice) plants. Gas chromatography confirmed gibberellic acid (GA) presence in the Hg2+ reducing bacteria Priestia megaterium RP1 (PMRP1), highlighting a potential link between CYP450 activity and plant health. This study demonstrates the promise of LSICY as a sustainable and effective approach for Hg2+ bioremediation, promoting a safer soil environment.


Assuntos
Biodegradação Ambiental , Sistema Enzimático do Citocromo P-450 , Giberelinas , Lipossomos , Mercúrio , Oryza , Sistema Enzimático do Citocromo P-450/metabolismo , Giberelinas/metabolismo , Giberelinas/farmacologia
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