Detalhe da pesquisa
1.
Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme.
Nature
; 581(7808): 323-328, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32433611
2.
Preparation and characterization of metal-substituted carotenoid cleavage oxygenases.
J Biol Inorg Chem
; 23(6): 887-901, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29946976
3.
Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center.
Biochemistry
; 56(22): 2836-2852, 2017 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28493664
4.
Key Residues for Catalytic Function and Metal Coordination in a Carotenoid Cleavage Dioxygenase.
J Biol Chem
; 291(37): 19401-12, 2016 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27453555
5.
Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Nat Chem Biol
; 11(6): 409-15, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25894083
6.
Utilization of Dioxygen by Carotenoid Cleavage Oxygenases.
J Biol Chem
; 290(51): 30212-23, 2015 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26499794
7.
Analysis of carotenoid isomerase activity in a prototypical carotenoid cleavage enzyme, apocarotenoid oxygenase (ACO).
J Biol Chem
; 289(18): 12286-99, 2014 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24648526
8.
Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.
Proc Natl Acad Sci U S A
; 109(41): E2747-56, 2012 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23012475
9.
Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes.
Proc Natl Acad Sci U S A
; 108(10): 3976-81, 2011 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21368113
10.
Structural basis of carotenoid cleavage: from bacteria to mammals.
Arch Biochem Biophys
; 539(2): 203-13, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23827316
11.
Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.
Nat Commun
; 14(1): 3100, 2023 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37248213
12.
The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification.
Nat Commun
; 14(1): 3533, 2023 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37316513
13.
Preparation of carotenoid cleavage dioxygenases for X-ray crystallography.
Methods Enzymol
; 671: 243-271, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35878980
14.
Seipin forms a flexible cage at lipid droplet formation sites.
Nat Struct Mol Biol
; 29(3): 194-202, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35210614
15.
Cryo-electron microscopy structure of the lipid droplet-formation protein seipin.
J Cell Biol
; 217(12): 4080-4091, 2018 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30327422