Detalhe da pesquisa
1.
Prednisolone and rapamycin reduce the plasma cell gene signature and may improve AAV gene therapy in cynomolgus macaques.
Gene Ther
; 31(3-4): 128-143, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37833563
2.
Efficacy and Safety of Abrilumab in a Randomized, Placebo-Controlled Trial for Moderate-to-Severe Ulcerative Colitis.
Gastroenterology
; 156(4): 946-957.e18, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30472236
3.
Acid test: lipid antigens get into the groove.
Immunity
; 28(6): 727-9, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18549793
4.
Clinical pharmacology of AMG 181, a gut-specific human anti-α4ß7 monoclonal antibody, for treating inflammatory bowel diseases.
Br J Clin Pharmacol
; 78(6): 1315-33, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24803302
5.
Mechanisms for glycolipid antigen-driven cytokine polarization by Valpha14i NKT cells.
J Immunol
; 184(1): 141-53, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19949076
6.
A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity.
J Immunol
; 184(4): 2107-15, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20083656
7.
Safety and Biological Activity of Rozibafusp alfa, a Bispecific Inhibitor of Inducible Costimulator Ligand and B Cell Activating Factor, in Patients With Rheumatoid Arthritis: Results of a Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study.
ACR Open Rheumatol
; 4(10): 903-911, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35899378
8.
Prednisolone reduces the interferon response to AAV in cynomolgus macaques and may increase liver gene expression.
Mol Ther Methods Clin Dev
; 24: 292-305, 2022 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35211641
9.
Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target.
Front Immunol
; 12: 782788, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34970265
10.
Efficacy and safety of abrilumab, an α4ß7 integrin inhibitor, in Japanese patients with moderate-to-severe ulcerative colitis: a phase II study.
Intest Res
; 17(3): 375-386, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-30739435
11.
Activation or anergy: NKT cells are stunned by alpha-galactosylceramide.
J Clin Invest
; 115(9): 2328-9, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16138189
12.
Brief Report: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multiple-Dose Study to Evaluate AMG 557 in Patients With Systemic Lupus Erythematosus and Active Lupus Arthritis.
Arthritis Rheumatol
; 70(7): 1071-1076, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29513931
13.
Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon-γ Antibody, in Patients With Discoid Lupus Erythematosus.
Arthritis Rheumatol
; 69(5): 1028-1034, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28118537
14.
Safety, pharmacokinetics and pharmacodynamics of AMG 811, an anti-interferon-γ monoclonal antibody, in SLE subjects without or with lupus nephritis.
Lupus Sci Med
; 4(1): e000226, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29018537
15.
A modified alpha-galactosyl ceramide for staining and stimulating natural killer T cells.
J Immunol Methods
; 312(1-2): 34-9, 2006 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-16647712
16.
Qa-1, a nonclassical class I histocompatibility molecule with roles in innate and adaptive immunity.
Immunol Res
; 29(1-3): 81-92, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15181272
17.
Co-receptor choice by V alpha14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection.
J Exp Med
; 207(5): 1015-29, 2010 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20404101
18.
Identification of pre- and postselection TCRalphabeta+ intraepithelial lymphocyte precursors in the thymus.
Immunity
; 25(4): 631-41, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17045820
19.
Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d.
Proc Natl Acad Sci U S A
; 103(11): 3972-7, 2006 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-16537470
20.
Immediate antigen-specific effector functions by TCR-transgenic CD8+ NKT cells.
Eur J Immunol
; 36(3): 570-82, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16506291