Detalhe da pesquisa
1.
In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy.
Antimicrob Agents Chemother
; 68(3): e0122223, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38265216
2.
Synthesis and evaluation of phenylimidazole FabK inhibitors as new Anti-C. Difficile agents.
Bioorg Med Chem
; 88-89: 117330, 2023 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37224699
3.
Recent Advances in Macrocyclic Drugs and Microwave-Assisted and/or Solid-Supported Synthesis of Macrocycles.
Molecules
; 27(3)2022 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164274
4.
Recent Reports of Solid-Phase Cyclohexapeptide Synthesis and Applications.
Molecules
; 23(6)2018 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29912160
5.
Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1.
Bioorg Med Chem Lett
; 27(24): 5393-5399, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29153737
6.
Solid-phase synthesis of cyclic hexapeptides wollamides A, B and desotamide B.
Tetrahedron Lett
; 58(27): 2675-2680, 2017 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29129945
7.
Synthesis and antibacterial evaluation of macrocyclic diarylheptanoid derivatives.
Bioorg Med Chem Lett
; 26(16): 4070-6, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27406794
8.
Determination of the absolute configuration of chaetoviridins and other bioactive azaphilones from the endophytic fungus Chaetomium globosum.
Bioorg Med Chem Lett
; 25(21): 4719-4723, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26343828
9.
Inhibitory effect of a callophycin A derivative on iNOS expression via inhibition of Akt in lipopolysaccharide-stimulated RAW 264.7 cells.
J Nat Prod
; 77(3): 527-35, 2014 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24299616
10.
Herbicidin congeners, undecose nucleosides from an organic extract of Streptomyces sp. L-9-10.
J Nat Prod
; 77(2): 227-33, 2014 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24533857
11.
Evaluation of Fusobacterium nucleatum Enoyl-ACP Reductase (FabK) as a Narrow-Spectrum Drug Target.
ACS Infect Dis
; 10(5): 1612-1623, 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38597503
12.
Macrocyclic drugs and synthetic methodologies toward macrocycles.
Molecules
; 18(6): 6230-68, 2013 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23708234
13.
Advancing Pharmacy Education by Moving From Sequenced "Integration" to True Curricular Integration.
Am J Pharm Educ
; 87(6): 100056, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37316122
14.
In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) Inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy.
bioRxiv
; 2023 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37790427
15.
Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NFκB inhibitors.
Org Biomol Chem
; 10(44): 8835-47, 2012 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23044819
16.
Microwave-assisted synthesis of macrocycles via intramolecular and/or bimolecular Ullmann coupling.
Tetrahedron Lett
; 53(32): 4173-4178, 2012 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23049146
17.
Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents.
Bioorg Med Chem
; 19(21): 6182-95, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21978950
18.
The structure-activity relationship of urea derivatives as anti-tuberculosis agents.
Bioorg Med Chem
; 19(18): 5585-95, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21840723
19.
Total synthesis and structural revision of engelhardione.
Tetrahedron Lett
; 52(35): 4570-4574, 2011 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-21927512
20.
Macrocycle-Antibiotic Hybrids: A Path to Clinical Candidates.
Front Chem
; 9: 659845, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33996753