Detalhe da pesquisa
1.
Pharmacokinetic/Pharmacodynamic Modeling of a Cell-Penetrating Peptide Phosphorodiamidate Morpholino Oligomer in mdx Mice.
Pharm Res
; 38(10): 1731-1745, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34671920
2.
Substituted diaryl ether compounds as retinoic acid-related orphan Receptor-γt (RORγt) agonists.
Bioorg Med Chem Lett
; 35: 127778, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33422603
3.
Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (RORγt) agonists.
Bioorg Med Chem Lett
; 30(12): 127204, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32334911
4.
Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity.
Bioorg Med Chem Lett
; 28(2): 85-93, 2018 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29233651
5.
Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo.
Drug Metab Dispos
; 44(7): 1123-38, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27098743
6.
Vitamin D receptor activation induces P-glycoprotein and increases brain efflux of quinidine: an intracerebral microdialysis study in conscious rats.
Pharm Res
; 32(3): 1128-40, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25319098
7.
Facile Preparation of Polysiloxane-Modified Asphalt Binder Exhibiting Enhanced Performance.
Polymers (Basel)
; 15(18)2023 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37765649
8.
The Prevalence, Risk Factors, and Prognosis of Acute Kidney Injury After Lung Transplantation: A Single-Center Cohort Study in China.
Transplant Proc
; 53(2): 686-691, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33334610
9.
Effect of Graphene on Modified Asphalt Microstructures Based on Atomic Force Microscopy.
Materials (Basel)
; 14(13)2021 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34279247
10.
Ribavirin Treatment for Critically Ill COVID-19 Patients: An Observational Study.
Infect Drug Resist
; 14: 5287-5291, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34916812
11.
Quantification of surrogate monoclonal antibodies in mouse serum using LC-MS/MS.
Bioanalysis
; 13(3): 147-159, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33543654
12.
Population Pharmacokinetic Analysis of BMS-986166, a Novel Selective Sphingosine-1-Phosphate-1 Receptor Modulator, and Exposure-Response Assessment of Lymphocyte Counts and Heart Rate in Healthy Participants.
Clin Pharmacol Drug Dev
; 10(1): 8-21, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33090733
13.
Bicyclic Ligand-Biased Agonists of S1P1: Exploring Side Chain Modifications to Modulate the PK, PD, and Safety Profiles.
J Med Chem
; 64(3): 1454-1480, 2021 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33492963
14.
Interplay of phase II enzymes and transporters in futile cycling: influence of multidrug resistance-associated protein 2-mediated excretion of estradiol 17beta-D-glucuronide and its 3-sulfate metabolite on net sulfation in perfused TR(-) and Wistar rat liver preparations.
Drug Metab Dispos
; 38(5): 769-80, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20124397
15.
Physiological modeling to understand the impact of enzymes and transporters on drug and metabolite data and bioavailability estimates.
Pharm Res
; 27(7): 1237-54, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20372987
16.
Effects of 1alpha,25-dihydroxyvitamin D3 on transporters and enzymes of the rat intestine and kidney in vivo.
Biopharm Drug Dispos
; 31(1): 91-108, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20013813
17.
Texture recognition of pulmonary nodules based on volume local direction ternary pattern.
Bioengineered
; 11(1): 904-920, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32815466
18.
A Nonenzymatic Glucose Sensor Platform Based on Specific Recognition and Conductive Polymer-Decorated CuCo2O4 Carbon Nanofibers.
Materials (Basel)
; 13(12)2020 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32604917
19.
Modeling and Simulation of the Pharmacokinetics and Target Engagement of an Antagonist Monoclonal Antibody to Interferon-γ-Induced Protein 10, BMS-986184, in Healthy Participants to Guide Therapeutic Dosing.
Clin Pharmacol Drug Dev
; 9(6): 689-698, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32068354
20.
Mesenteric Lymph Duct Drainage Attenuates Lung Inflammatory Injury and Inhibits Endothelial Cell Apoptosis in Septic Rats.
Biomed Res Int
; 2020: 3049302, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33145344