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1.
Curr Opin Anaesthesiol ; 25(6): 699-718, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23103844

RESUMO

PURPOSE OF REVIEW: There is an increasing importance of incorporating mobile computing into the academic medical environment. A growing majority of physicians, residents and medical students currently use mobile devices for education, access to clinical information and to facilitate bedside care. Therefore, it is important to assess the current opportunities and challenges in the use of mobile computing devices in the academic medical environment. RECENT FINDINGS: Current research has found that a majority of physicians, residents and medical students either own or use mobile devices. In addition, studies have shown that these devices are effective as educational tools, resource guides and aids in patient care. Although there are opportunities for medical education, issues of deployment must still be addressed, such as privacy, connectivity, standardization and professionalism. SUMMARY: Understanding the opportunities and challenges of using mobile computing devices in the academic medical environment can help determine the feasibility and benefits of their use for individuals and institutions.


Assuntos
Anestesiologia/economia , Metodologias Computacionais , Educação Médica/tendências , Centros Médicos Acadêmicos/tendências , Anestesiologia/tendências , Competência Clínica , Hospitais Universitários , Humanos , Privacidade
2.
Biomaterials ; 34(16): 4038-4047, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-23480958

RESUMO

Endothelial cells (ECs) are aligned longitudinally under laminar flow, whereas they are polygonal and poorly aligned in regions of disturbed flow. The unaligned ECs in disturbed flow fields manifest altered function and reduced survival that promote lesion formation. We demonstrate that the alignment of the ECs may directly influence their biology, independent of fluid flow. We developed aligned nanofibrillar collagen scaffolds that mimic the structure of collagen bundles in blood vessels, and examined the effects of these materials on EC alignment, function, and in vivo survival. ECs cultured on 30-nm diameter aligned fibrils re-organized their F-actin along the nanofibril direction, and were 50% less adhesive for monocytes than the ECs grown on randomly oriented fibrils. After EC transplantation into both subcutaneous tissue and the ischemic hindlimb, EC viability was enhanced when ECs were cultured and implanted on aligned nanofibrillar scaffolds, in contrast to non-patterned scaffolds. ECs derived from human induced pluripotent stem cells and cultured on aligned scaffolds also persisted for over 28 days, as assessed by bioluminescence imaging, when implanted in ischemic tissue. By contrast, ECs implanted on scaffolds without nanopatterning generated no detectable bioluminescent signal by day 4 in either normal or ischemic tissues. We demonstrate that 30-nm aligned nanofibrillar collagen scaffolds guide cellular organization, modulate endothelial inflammatory response, and enhance cell survival after implantation in normal and ischemic tissues.


Assuntos
Forma Celular/efeitos dos fármacos , Colágeno/farmacologia , Células Endoteliais/citologia , Nanofibras/química , Alicerces Teciduais/química , Animais , Anisotropia , Bovinos , Adesão Celular/efeitos dos fármacos , Sobrevivência Celular/efeitos dos fármacos , Técnicas de Cocultura , Células Endoteliais/efeitos dos fármacos , Células Endoteliais/metabolismo , Células Endoteliais/ultraestrutura , Membro Posterior/irrigação sanguínea , Membro Posterior/efeitos dos fármacos , Membro Posterior/patologia , Humanos , Isquemia/terapia , Masculino , Membranas Artificiais , Camundongos , Miócitos de Músculo Liso/citologia , Miócitos de Músculo Liso/efeitos dos fármacos , Miócitos de Músculo Liso/ultraestrutura , Nanofibras/ultraestrutura , Tamanho da Partícula , Fenótipo , Implantação de Prótese , Tela Subcutânea/efeitos dos fármacos
3.
Best Pract Res Clin Anaesthesiol ; 26(1): 33-53, 2012 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-22559955

RESUMO

Today's educators are faced with substantial challenges in the use of information technology for anaesthesia training and continuing medical education. Millennial learners have uniquely different learning styles than previous generations of students. These preferences distinctly incorporate the use of digital information technologies and social technologies to support learning. To be effective teachers, modern educators must be familiar with these new information technologies and understand how to use them for medical education. Examples of new information technologies include learning management systems, lecture capture, social media (YouTube, Flickr), social networking (Facebook), Web 2.0, multimedia (video learning triggers and point-of-view video) and mobile computing applications. The information technology challenges for educators in the twenty-first century include: (a) understanding how technology shapes the learning preferences of today's anaesthesia residents, (b) distinguishing between the function and properties of new learning technologies and (c) properly using these learning technologies to enhance the anaesthesia curriculum.


Assuntos
Anestesiologia/educação , Instrução por Computador/métodos , Educação Médica Continuada/métodos , Currículo , Educação Médica/métodos , Tecnologia Educacional , Docentes de Medicina , Humanos , Internato e Residência
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