Detalhe da pesquisa
1.
A novel 12-membered ring non-antibiotic macrolide EM982 attenuates cytokine production by inhibiting IKKß and IκBα phosphorylation.
J Biol Chem
; : 107384, 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38762177
2.
In vitro and in vivo activities of KSP-1007, a broad-spectrum inhibitor of serine- and metallo-ß-lactamases, in combination with meropenem against carbapenem-resistant Gram-negative bacteria.
Antimicrob Agents Chemother
; : e0160223, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38709005
3.
Nanaomycin E inhibits NLRP3 inflammasome activation by preventing mitochondrial dysfunction.
Int Immunol
; 34(10): 505-518, 2022 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35759801
4.
Hakuhybotrol, a polyketide produced by Hypomyces pseudocorticiicola, characterized with the assistance of 3D ED/MicroED.
Org Biomol Chem
; 21(11): 2320-2330, 2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36815714
5.
A new selective inhibitor for IMP-1 metallo-ß-lactamase, 3Z,5E-octa-3,5-diene-1,3,4-tricarboxylic acid-3,4-anhydride.
Bioorg Med Chem
; 78: 117109, 2023 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36603397
6.
Studies on the Catechin Constituents of Bark of Cinnamomum sieboldii.
Chem Pharm Bull (Tokyo)
; 71(5): 374-379, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37121688
7.
Chemical Degradation-Inspired Total Synthesis of the Antibiotic Macrodiolide, Luminamicin.
J Am Chem Soc
; 144(50): 23148-23157, 2022 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36487183
8.
Koshidacins A and B, Antiplasmodial Cyclic Tetrapeptides from the Okinawan Fungus Pochonia boninensis FKR-0564.
J Nat Prod
; 85(11): 2641-2649, 2022 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36282784
9.
Structure, solubility, and permeability relationships in a diverse middle molecule library.
Bioorg Med Chem Lett
; 37: 127847, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33571648
10.
Discoveries and Syntheses of Highly Potent Antimalarial Troponoids.
Chem Pharm Bull (Tokyo)
; 69(6): 564-572, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34078803
11.
The Nonantibiotic Macrolide EM900 Attenuates House Dust Mite-Induced Airway Inflammation in a Mouse Model of Obesity-Associated Asthma.
Int Arch Allergy Immunol
; 181(9): 665-674, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32599580
12.
The non-antibiotic macrolide EM900 attenuates HDM and poly(I:C)-induced airway inflammation with inhibition of macrophages in a mouse model.
Inflamm Res
; 69(1): 139-151, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31820024
13.
Synthesis and Evaluation of Antibacterial Activity of Bottromycins.
J Org Chem
; 83(13): 7135-7149, 2018 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29560726
14.
Pestynol, an Antifungal Compound Discovered Using a Saccharomyces cerevisiae 12geneΔ0HSR-iERG6-Based Assay.
J Nat Prod
; 81(7): 1604-1609, 2018 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29975062
15.
The Design, Synthesis, and Evaluation of 1,5,7-Trisubstituted-3-Pyridyl-Xanthones for Use as Insecticides Starting from Pyripyropeneâ A.
Chemistry
; 22(51): 18450-18455, 2016 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27862416
16.
Narrow-spectrum inhibitors targeting an alternative menaquinone biosynthetic pathway of Helicobacter pylori.
J Infect Chemother
; 22(9): 587-92, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27346378
17.
Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor.
Proc Natl Acad Sci U S A
; 110(40): 15892-7, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24043811
18.
Organocatalytic Site-Selective Acylation of 10-Deacetylbaccatin III.
Chem Pharm Bull (Tokyo)
; 64(7): 907-12, 2016 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26903156
19.
In Situ Click Chemistry for the Identification of a Potent D-Amino Acid Oxidase Inhibitor.
Chem Pharm Bull (Tokyo)
; 64(7): 695-703, 2016 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26686243
20.
Organocatalytic Site-Selective Acylation of Avermectin B2a, a Unique Endectocidal Drug.
Chem Pharm Bull (Tokyo)
; 64(7): 856-64, 2016 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27075247