[What are the characteristic signs of cholecystolithiasis in patients with type 2 diabetes?]. / Jaké jsou charakteristické znaky cholecystolitiázy u nemocných s cukrovkou 2. typu?

In a group of 166 patients with type 2 diabetes mellitus, hospitalized at the First Medical Clinic, Faculty Hospital Prague 5-Motol, cholecystolithiasis was found in 91. In these patients sonographic parameters were analyzed. All were hospitalized primarily on account of a non-biliary indications. The group comprised 67 men, mean age 69 years. The control group was formed by 67 patients with a normal glucose tolerance. An enlarged gallbladder was found in 15 patients (16.4%), a gallbladder of reduced size in 8 (8.8%). Stones smaller than 1 cm were in the group of diabetics in 31 subjects (34.3%), stones larger than 1 cm in 60 (65.7%). A wall of the gallbladder wider than 3.5 mm was found in 14 (15.4%) diabetics with cholecystolithiasis. All these results were statistically significant as compared with the control group (p < 0.01). There was no significant difference in the number of stones in diabetics and controls. The authors discuss the causes of these findings. In the conclusion the authors state that it is necessary to seek actively cholecystolithiasis in type 2 diabetics and indicate cholecystectomy in time to prevent numerous, in particular inflammatory, complications. For detection ultrasonography is suited best.

[Cholecystolithiasis in type II diabetics]. / Cholecystolitiáza u diabetiku II. typu.

In a group of 166 type II diabetics hospitalized in a medical department the authors made clinical and ultrasonographic examinations focused on the presence of cholecystolithiasis. The control group was formed by 67 subjects with normal glucose tolerance. None of the patients were hospitalized on account of biliary disease. The purpose of the work was to 1. evaluate the difference in the incidence of cholecystolithiasis in diabetic patients and controls with regard to age and sex, 2. to assess differences in the incidence of obesity, impaired lipid metabolism and a positive biliary family--history in diabetics and controls with lithiasis, 3. to evaluate diabetes and the presence of microalbuminuria. In the authors' group cholecystolithiasis is significantly more frequent in diabetics as compared with controls, in men, women and people above 65 years (p less than 0.01). The group of diabetics and controls with lithiasis does not differ as to the incidence of obesity, hyperlipoproteinaemia and positive family-history of biliary disease. No significant differences in parameters of compensation of diabetes nor differences in the incidence of microalbuminuria were found between diabetics with and without lithiasis. The results suggest that it is useful to screen cholecystolithiasis in diabetic subjects.