Detalhe da pesquisa
1.
Mutational profile of the regenerative process and de novo genome assembly of the planarian Schmidtea polychroa.
Nucleic Acids Res
; 52(4): 1779-1792, 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38180823
2.
Epistasis, aneuploidy, and functional mutations underlie evolution of resistance to induced microtubule depolymerization.
EMBO J
; 40(22): e108225, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34605051
3.
DNA mismatch repair protects the genome from oxygen-induced replicative mutagenesis.
Nucleic Acids Res
; 51(20): 11040-11055, 2023 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37791890
4.
Characterisation of the spectrum and genetic dependence of collateral mutations induced by translesion DNA synthesis.
PLoS Genet
; 18(2): e1010051, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35130276
5.
BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model.
Proc Natl Acad Sci U S A
; 118(41)2021 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34607954
6.
Potential Association of Cytochrome P450 Copy Number Alteration in Tumour with Chemotherapy Resistance in Lung Adenocarcinoma Patients.
Int J Mol Sci
; 24(17)2023 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37686184
7.
A comparative analysis of the mutagenicity of platinum-containing chemotherapeutic agents reveals direct and indirect mutagenic mechanisms.
Mutagenesis
; 36(1): 75-86, 2021 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33502495
8.
Establishment and Characterization of a Brca1-/-, p53-/- Mouse Mammary Tumor Cell Line.
Int J Mol Sci
; 21(4)2020 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32053991
9.
The genomic imprint of cancer therapies helps timing the formation of metastases.
Int J Cancer
; 145(3): 694-704, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30694556
10.
Long-term treatment with the PARP inhibitor niraparib does not increase the mutation load in cell line models and tumour xenografts.
Br J Cancer
; 119(11): 1392-1400, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30425352
11.
Probing the biological consequences of a previously undescribed de novo mutation of ZMYND11 in a schizophrenia patient by CRISPR genome editing and induced pluripotent stem cell based in vitro disease-modeling.
Schizophr Res
; 2024 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38290943
12.
Increased frequency of CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression without inducing homologous recombination deficiency.
Res Sq
; 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38645014
13.
Simultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions.
PLoS Genet
; 6(10)2010 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20949111
14.
Probing telomeric-like G4 structures with full or partial 2'-deoxy-5-hydroxyuridine substitutions.
Biochimie
; 214(Pt A): 33-44, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36707016
15.
Spontaneous mutagenesis in human cells is controlled by REV1-Polymerase ζ and PRIMPOL.
Cell Rep
; 42(8): 112887, 2023 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37498746
16.
A fresh look at somatic mutations in cancer.
Science
; 376(6591): 351-352, 2022 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35446665
17.
Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers.
Cell Rep
; 38(12): 110555, 2022 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35320711
18.
BRCA1 deficiency specific base substitution mutagenesis is dependent on translesion synthesis and regulated by 53BP1.
Nat Commun
; 13(1): 226, 2022 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35017534
19.
Evaluation and modulation of DNA lesion bypass in an SV40 large T antigen-based in vitro replication system.
FEBS Open Bio
; 11(4): 1054-1075, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33512058
20.
A subset of lung cancer cases shows robust signs of homologous recombination deficiency associated genomic mutational signatures.
NPJ Precis Oncol
; 5(1): 55, 2021 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34145376