Detalhe da pesquisa
1.
SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion.
Cell
; 187(4): 861-881.e32, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38301646
2.
Replication stress impairs chromosome segregation and preimplantation development in human embryos.
Cell
; 185(16): 2988-3007.e20, 2022 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35858625
3.
Functional interrogation of DNA damage response variants with base editing screens.
Cell
; 184(4): 1081-1097.e19, 2021 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33606978
4.
Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination.
Mol Cell
; 83(13): 2347-2356.e8, 2023 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37311462
5.
REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps.
Mol Cell
; 81(19): 4008-4025.e7, 2021 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34508659
6.
HATtracting Nucleases to Stalled Forks.
Mol Cell
; 80(2): 177-180, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33065018
7.
Extrachromosomal telomere DNA derived from excessive strand displacements.
Proc Natl Acad Sci U S A
; 121(19): e2318438121, 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38696464
8.
The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection.
Mol Cell
; 72(1): 127-139.e8, 2018 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30244837
9.
Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers.
Mol Cell
; 68(2): 414-430.e8, 2017 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29053959
10.
Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity.
Mol Cell
; 67(5): 882-890.e5, 2017 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28886337
11.
Strand annealing and motor driven activities of SMARCAL1 and ZRANB3 are stimulated by RAD51 and the paralog complex.
Nucleic Acids Res
; 50(14): 8008-8022, 2022 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35801922
12.
BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks.
Cell Rep
; 43(4): 114006, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38554279
13.
Extrachromosomal Telomeres Derived from Excessive Strand Displacements.
bioRxiv
; 2023 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37577643
14.
Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination.
Cell Rep
; 42(4): 112296, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36961817
15.
CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue.
bioRxiv
; 2023 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38234835
16.
Partial loss-of-function mutations in GINS4 lead to NK cell deficiency with neutropenia.
JCI Insight
; 7(21)2022 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36345943
17.
Time for remodeling: SNF2-family DNA translocases in replication fork metabolism and human disease.
DNA Repair (Amst)
; 95: 102943, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32971328
18.
MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage.
Nat Commun
; 11(1): 2948, 2020 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32528060
19.
Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant.
Nat Commun
; 10(1): 3395, 2019 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31363085