Detalhe da pesquisa
1.
The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy.
J Mol Cell Cardiol
; 66: 27-40, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24161911
2.
Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity.
Circ Res
; 110(6): 841-50, 2012 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22343711
3.
Tetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament properties.
J Mol Cell Cardiol
; 56: 44-54, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23247392
4.
Src homology 2 domain-containing phosphatase 2 (Shp2) is a component of the A-kinase-anchoring protein (AKAP)-Lbc complex and is inhibited by protein kinase A (PKA) under pathological hypertrophic conditions in the heart.
J Biol Chem
; 287(48): 40535-46, 2012 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23045525
5.
The ß-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calcium.
Am J Physiol Heart Circ Physiol
; 305(6): H856-66, 2013 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23873795
6.
Post-translational modifications of myofilament proteins involved in length-dependent prolongation of relaxation in rabbit right ventricular myocardium.
Arch Biochem Biophys
; 535(1): 22-9, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23085150
7.
Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart.
Circulation
; 124(24): 2702-15, 2011 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22082674
8.
p21-activated kinase improves cardiac contractility during ischemia-reperfusion concomitant with changes in troponin-T and myosin light chain 2 phosphorylation.
Am J Physiol Heart Circ Physiol
; 302(1): H224-30, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22037191
9.
Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A.
J Mol Cell Cardiol
; 51(6): 988-96, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21971074
10.
Limiting sarcolemmal Na+ entry during resuscitation from ventricular fibrillation prevents excess mitochondrial Ca2+ accumulation and attenuates myocardial injury.
J Appl Physiol (1985)
; 103(1): 55-65, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17431086
11.
Metabolic efficiency promotes protection from pressure overload in hearts expressing slow skeletal troponin I.
Circ Heart Fail
; 8(1): 119-27, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25424393
12.
P21-activated kinase in inflammatory and cardiovascular disease.
Cell Signal
; 26(9): 2060-9, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24794532
13.
Cholesterol regulation of PIP(2): why cell type is so important.
Front Physiol
; 3: 492, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23316171