1.
Bioorg Med Chem Lett
; 17(12): 3463-7, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17459703
RESUMO
The development of a series of novel aminopyrimidines as inhibitors of c-Jun N-terminal kinases is described. The synthesis, in vitro inhibitory values for JNK1, JNK2 and CDK2, and the in vitro inhibitory value for a c-Jun cellular assay are discussed.