RESUMO
After orotracheal intubation of a 30-year-old man with a flexible tube, a floating foreign body was noticed inside the tube. The subsequent bronchoscopy revealed a second foreign body near the bifurcation of the trachea. Both foreign bodies were removed successfully and identified as parts of the plastic-sheathed stylet. Fatigue of material is discussed as the reason for the broken reusable stylet during intubation.
Assuntos
Broncoscópios/efeitos adversos , Corpos Estranhos/etiologia , Intubação Intratraqueal/efeitos adversos , Doenças da Traqueia/etiologia , Adulto , Broncoscopia , Falha de Equipamento , Corpos Estranhos/terapia , Humanos , Masculino , Estresse Mecânico , Doenças da Traqueia/terapiaRESUMO
Different phenylalkyl backbone modified antisense oligonucleotides complementary to the Hepatitis C virus (HCV) RNA nucleotides 326-342 were synthesized. The lipohilic character of modified oligonucleotides was determined from RP-HPLC retention times. The inhibitory effect of these antisense oligonucleotides on HCV gene expression was analyzed in an in vitro test system.