Detalhe da pesquisa
1.
Structural Analyses of Designed α-Helix and ß-Sheet Peptide Nanofibers Using Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy and Introduction of Structure-Based Metal-Responsive Properties.
Int J Mol Sci
; 25(2)2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38256184
2.
Pathway Dependence of the Formation and Development of Prefibrillar Aggregates in Insulin B Chain.
Molecules
; 27(13)2022 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35807211
3.
Microenvironment pH-Induced Selective Cell Death for Potential Cancer Therapy Using Nanofibrous Self-Assembly of a Peptide Amphiphile.
Biomacromolecules
; 22(6): 2524-2531, 2021 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33960189
4.
Structural Insights into the Inhibition of Amyloid Fibril Formation by Fibrinogen via Interaction with Prefibrillar Intermediates.
Biochemistry
; 58(24): 2769-2781, 2019 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31135143
5.
In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction.
Proc Natl Acad Sci U S A
; 110(20): 8182-7, 2013 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23630290
6.
Designing cell-aggregating peptides without cytotoxicity.
Biomacromolecules
; 15(2): 512-23, 2014 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24432760
7.
Hyper Thermostability and Liquid-Crystal-Like Properties of Designed α-Helical Peptide Nanofibers.
J Phys Chem B
; 127(39): 8331-8343, 2023 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751540
8.
Solution structure of the state 1 conformer of GTP-bound H-Ras protein and distinct dynamic properties between the state 1 and state 2 conformers.
J Biol Chem
; 286(45): 39644-53, 2011 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21930707
9.
Critical roles of interactions among switch I-preceding residues and between switch II and its neighboring alpha-helix in conformational dynamics of the GTP-bound Ras family small GTPases.
J Biol Chem
; 286(17): 15403-12, 2011 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-21388959
10.
In Situ Synthesis of an Anticancer Peptide Amphiphile Using Tyrosine Kinase Overexpressed in Cancer Cells.
JACS Au
; 2(9): 2023-2028, 2022 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36186562
11.
Inhibition of Melittin Activity Using a Small Molecule with an Indole Ring.
J Phys Chem B
; 126(31): 5793-5802, 2022 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35913127
12.
Structural basis for conformational dynamics of GTP-bound Ras protein.
J Biol Chem
; 285(29): 22696-705, 2010 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20479006
13.
Molecular Design of pH-Responsive Helix Peptides That Can Damage Tumor Cells Selectively.
ACS Appl Bio Mater
; 4(3): 2442-2452, 2021 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35014363
14.
NMR based structure-activity relationship analysis of an antimicrobial peptide, thanatin, engineered by site-specific chemical modification: Activity improvement and spectrum alteration.
Biochem Biophys Res Commun
; 369(2): 609-15, 2008 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18294955
15.
Two conformational states of Ras GTPase exhibit differential GTP-binding kinetics.
Biochem Biophys Res Commun
; 369(2): 327-32, 2008 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18291096
16.
A specific form of prefibrillar aggregates that functions as a precursor of amyloid nucleation.
Sci Rep
; 8(1): 62, 2018 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311640
17.
Transformation of an alpha-helix peptide into a beta-hairpin induced by addition of a fragment results in creation of a coexisting state.
Proteins
; 66(4): 860-8, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17177204
18.
Characterization of heme-coordinating histidyl residues of cytochrome b5 based on the reactivity with diethylpyrocarbonate: a mechanism for the opening of axial imidazole rings.
J Biochem
; 140(4): 561-71, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16963788
19.
De novo design of foldable proteins with smooth folding funnel: automated negative design and experimental verification.
Structure
; 11(5): 581-90, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12737823
20.
Broadband Dielectric Spectroscopy on Lysozyme in the Sub-Gigahertz to Terahertz Frequency Regions: Effects of Hydration and Thermal Excitation.
J Phys Chem B
; 120(21): 4743-55, 2016 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27158918