Detalhe da pesquisa
1.
Design, synthesis and biological evaluation of pyrazolyl-nitroimidazole derivatives as potential EGFR/HER-2 kinase inhibitors.
Bioorg Med Chem Lett
; 26(2): 677-683, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26652482
2.
Synthesis, biological evaluation, and molecular docking studies of novel 2-styryl-5-nitroimidazole derivatives containing 1,4-benzodioxan moiety as FAK inhibitors with anticancer activity.
Bioorg Med Chem
; 22(11): 2947-54, 2014 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24792811
3.
Metronidazole containing pyrazole derivatives potently inhibit tyrosyl-tRNA synthetase: design, synthesis, and biological evaluation.
Chem Biol Drug Des
; 88(4): 592-8, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27206529
4.
Synthesis and Biological Evaluation of 1-Methyl-1H-indole-Pyrazoline Hybrids as Potential Tubulin Polymerization Inhibitors.
ChemMedChem
; 11(13): 1446-58, 2016 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27159418
5.
Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents.
Sci Rep
; 6: 25387, 2016 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27138035
6.
Modification, biological evaluation and 3D QSAR studies of novel 2-(1,3-diaryl- 4,5-dihydro-1H-pyrazol-5-yl)phenol derivatives as inhibitors of B-Raf kinase.
PLoS One
; 9(5): e95702, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24827980
7.
Discovery and molecular modeling of novel 1-indolyl acetate--5-nitroimidazole targeting tubulin polymerization as antiproliferative agents.
Eur J Med Chem
; 85: 341-51, 2014 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25105922