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1.
Pediatr Int ; 64(1): e15008, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34599634

RESUMO

BACKGROUND: In this study, eating behaviors and alexithymia levels in obese adolescents were investigated. Relationships between alexithymia, eating behavior and insulin resistance were studied. METHODS: The patient group consisted of 87 obese adolescents or overweight adolescents (O + OW). The comparison group consisted of 101 normal weight adolescents (N). Alexithymia Questionnaire for Children, Dutch Eating Behavior Questionnaire, and Revised Child Anxiety and Depression Scale-Child Version, are used for assessing adolescents. The homeostasis model assessment-estimated insulin resistance was calculated to determine insulin resistance. RESULTS: Alexithymia Questionnaire for Children scores were significantly higher in O + OW than N (P = 0.009). Both emotional and restrained eating scores are higher in O + OW (P < 0.001 for both). On the other hand, external eating scores were not significantly different. In O + OW, external eating was positively associated with homeostasis model assessment-estimated insulin resistance (r: 035, P = 0.006), but is not associated with fasting blood glucose and the hemoglobin A1c (HbA1c) (r: -0.05, P = 0.62; r: -0.05, P = 0.73). Regression analysis showed that restrained and emotional eating were predictors of O + OW (B: 0.1, P < 0.001; B: 0.06, P = 0.001). Emotional eating was positively correlated with the Alexithymia Questionnaire for Children and Revised Child Anxiety and Depression Scale-Child Version in O + OW (r: 0.29, P = 0.008; r: 0.48, P < 0.001). CONCLUSIONS: Obese and overweight adolescents were more alexithymic than normal weight adolescents. Alexithymia scores were also positively associated with emotional eating. On the other hand, alexithymia was not a predictor of obesity/overweight. Restrained and emotional eating were predictors of obesity/overweight. Emotional and restrained eating were more common in obese and overweight adolescents than normal-weight adolescents. External eating is not significantly associated with obesity but is related to insulin resistance.


Assuntos
Obesidade , Sobrepeso , Adolescente , Índice de Massa Corporal , Emoções , Comportamento Alimentar/psicologia , Humanos , Obesidade/complicações , Obesidade/epidemiologia , Sobrepeso/complicações , Sobrepeso/epidemiologia , Inquéritos e Questionários
2.
Arch Sex Behav ; 50(3): 885-895, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-33694048

RESUMO

We compared gender dysphoria (GD) patients and their same-sex siblings in terms of their 2D:4D ratios, which may reflect prenatal exposure to androgen, one of the possible etiological mechanisms underlying GD. Sixty-eight GD patients (46 Female-to-Male [FtM]; 22 Male-to-Female [MtF]), 68 siblings (46 sisters of FtMs; 22 brothers of MtFs), and 118 heterosexual controls (62 female; 56 male) were included in the study. FtMs were gynephilic and MtFs were androphilic. We found that 2D:4D ratios in the both right hand (p < .001) and the left hand (p = .003) were lower in male controls than in female controls. Regarding right hands, FtM GD patients had lower 2D:4D ratios than female controls (p < .001) but their ratios did not differ from those of their sisters or male controls. FtM GD patients had no significant difference in their left-hand 2D:4D ratios compared to their sisters or female and male controls. While there was no significant difference in right hands between FtM's sisters and male controls, left-hand 2D:4D ratios were significantly higher in FtM's sisters (p = .017). MtF GD patients had lower right-hand 2D:4D ratios than female controls (p <.001), but their right-hand ratios did not differ from those of their brothers and male controls. There was no significant difference in left-hand 2D:4D ratios between MtF GD patients, and their brothers, or female and male controls. FtM GD patients showed significantly masculinized right-hand 2D:4D ratios, while there was no evidence of feminization in MtF GD patients.


Assuntos
Disforia de Gênero/psicologia , Heterossexualidade/psicologia , Caracteres Sexuais , Transexualidade/psicologia , Adulto , Feminino , Humanos , Masculino , Irmãos , Adulto Jovem
3.
Qual Life Res ; 28(4): 1097-1103, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30578453

RESUMO

INTRODUCTION: Functional impairment in attention deficit hyperactivity disorder (ADHD) can occur in many areas such as in family, social activities, and problems related to school and may also persist during adulthood. The Weiss Functional Impairment Rating Scale-Parent Form (WFIRS-P) is designed to measure the functional impairment related to ADHD symptoms. The aim of this study was to determine the level of functional impairment that distinguishes the patients with ADHD who were diagnosed through semi-structured interviews from those without ADHD. METHOD: This study consists of ADHD patients who were diagnosed through semi-structured interview aged 5-18 years (n = 250) and same age gender-matched healthy controls (n = 250). A receiver operating characteristic (ROC) curve was constructed by calculating the sensitivity and specificity of the scale cut-off values. RESULTS: An area under the curve (AUC) of 0.974 (95% CI 0.956-0.986) was found in this study. For WFIRS-P subdomains, AUC curves, which range from 0.76 to 0.95, were also having strong power for differentiation between groups. The optimal cut-off value for WFIRS-P using Youden's J Index is 0.32. There is no significant gender and age group differences in AUC for either the total or subdomain scores. CONCLUSION: Our findings provide that Turkish version of WFIRS-P could be a reliable way of distinguishing the level of functional impairment in ADHD from controls.


Assuntos
Transtorno do Deficit de Atenção com Hiperatividade/psicologia , Qualidade de Vida/psicologia , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Curva ROC
4.
Biomarkers ; 21(7): 614-8, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27097671

RESUMO

CONTEXT: Improved biomarkers would facilitate the diagnosis and treatment of autism spectrum disorders (ASD). OBJECTIVE: Our objective was to examine the levels of Nogo-A and glial fibrillary acidic protein (GFAP) in children with ASD. MATERIALS AND METHODS: Serum concentrations of GFAP and Nogo-A were determined by enzyme-linked immunosorbent assay. RESULTS: In this preliminary study, we found that serum Nogo-A was not found significantly different between groups, while serum levels of GFAP were significantly lower in ASD than controls. DISCUSSION AND CONCLUSIONS: It will be of great interest to determine other potential causes of elevated serum levels of GFAP, and whether this elevation has any phenotypic effect.


Assuntos
Transtorno do Espectro Autista/sangue , Proteína Glial Fibrilar Ácida/sangue , Proteínas Nogo/sangue , Biomarcadores/sangue , Estudos de Casos e Controles , Criança , Ensaio de Imunoadsorção Enzimática , Humanos
5.
Neuropediatrics ; 46(6): 410-5, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26479762

RESUMO

α-Synuclein (α-syn) and tau proteins are thought to be related with the synaptic loss and cell death underlying several important neurodegenerative diseases. The aim of our study was to investigate serum α-syn and tau levels in autism. Serum levels of α-syn and tau were measured, and autism spectrum disorder (ASD) severity was assessed at admission using the Childhood Autism Rating Scale (CARS) total score. The mean CARS score of the autism group on admission was 47.91 points (SD: 5.97). The results indicated that the mean serum α-syn and serum tau levels were significantly (p < 0.001) lower in children with ASD as compared with normal cases (33.01 ± 20.78 and 55.19 ± 15.34 ng/mL and 241.23 ± 290.5 and 509.78 ± 269.25 ng/mL, respectively). There was a significant positive correlation between serum α-syn levels and serum levels of tau identified by Pearson correlation analysis (r = 0.922, n = 28, p < 0.001). Synaptic abnormality in autism may result from microglial activity. Furthermore, α-syn and tau aggregation may lead to synaptic dysfunction, and this may contribute to either neuronal or synaptic dysfunction or neurodegeneration. Our preliminary study suggests that low levels of serum α-syn and tau may be implicated in the relationship between synaptic activity and autism.


Assuntos
Transtorno do Espectro Autista/sangue , alfa-Sinucleína/sangue , Proteínas tau/sangue , Estudos de Casos e Controles , Criança , Pré-Escolar , Feminino , Humanos , Masculino
6.
Sleep Sci ; 17(1): e112-e114, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38545246

RESUMO

Neuropsychiatric manifestations that have developed after coronavirus disease 2019 (COVID-19) infection have not been fully clarified yet. Persistent insomnia and consequent significant impairment in daily functioning is an unexpected symptom of COVID-19 infection. In this case report, a 13-year-old female patient who presented with complaint of insomnia starting with COVID-19 infection is discussed. The patient showed significant improvement with melatonin treatment and maintained her wellbeing in the follow-up. Melatonin may be a useful option to treat COVID-19-related brief insomnia in adolescents. Our case report will be a step forward to help clinicians examine the underlying neurovegetative mechanisms, such as sleep, to improve patients wellbeing. HEADINGS: COVID-19. Melatonin. Sleep Initiation and Maintenance Disorders.

7.
Appl Neuropsychol Child ; : 1-9, 2024 May 17.
Artigo em Inglês | MEDLINE | ID: mdl-38757958

RESUMO

OBJECTIVE: Sleep problems and executive dysfunction are associated with functional impairment in children with neurodevelopmental disorders. In this study, we aimed to investigate these aspects in children with Specific Learning Disorders (SLD) and SLD with comorbid Attention-Deficit Hyperactivity Disorder (ADHD), while also evaluating differences with typically developing (TD) children. Our study hypothesizes that children with SLD, especially those with comorbid ADHD, face greater sleep disturbances and executive function challenges compared to TD peers. We also propose that sleep disturbances aggravate functional impairment and that executive functions mediate this relationship. METHOD: The data obtained from psychiatric evaluations, semi-structured interviews and questionnaires filled out by parents were analyzed. RESULTS: SLD + ADHD group had worse scores in all scales, followed by SLD and TD groups. Mediator analysis demonstrated that executive functions had a mediator role in the relationship between sleep problems and functional impairment. CONCLUSION: Our findings suggest that children with SLD experience more significant difficulties in daily living than their typically developing peers and having ADHD comorbidity, poor executive functions, and additional sleep problems can further exacerbate impairment. Notably, our mediation analysis suggests that executive functions mediate the relationship between sleep disturbances and the severity of functional impairments.

8.
Arch Dermatol Res ; 316(6): 260, 2024 May 25.
Artigo em Inglês | MEDLINE | ID: mdl-38795219

RESUMO

Alopecia areata (AA) is an autoimmune disease that develops due to inflammation and causes sudden hair loss. Ithas been observed that family circumstances may contribute to the development of AA. This study aims to assessthe relationship between the development of alopecia areata in children, family functions, and depression andanxiety levels in their parents.Thirty-nine participants diagnosed with AA and 41 healthy controls (HC), agedbetween 8 and 18 years, and their parents participated in the study. The assessment of the children included thecompletion of a socio-demographic data form, the Parenting Style Scale (PSS), and the Revised Children's Anxietyand Depression Scale (RCADS). The parents provided information on a sociodemographic form, the BeckDepression Inventory (BDI), and the Beck Anxiety Inventory (BAI). The children in the control group scoredsignificantly higher on the PSS acceptance/ involvement subscale than those with AA. In the AA group, the numberof authoritative and indulgent (PSS) families was statistically significantly lower than that of the families in the HC,and the number of neglectful families was statistically significantly higher than those of the control group. Totalanxiety and depression t scores (RCADS) were statistically significantly higher in the AA children than in theHC. Our study demonstrates the importance of considering familial factors and parental mental health tounderstand and address alopecia areata in children. Our findings support the psychosomatic component of AA.Implementing comprehensive treatment strategies that target psychological well-being and family dynamics couldprove crucial.


Assuntos
Alopecia em Áreas , Ansiedade , Depressão , Poder Familiar , Humanos , Alopecia em Áreas/psicologia , Alopecia em Áreas/imunologia , Alopecia em Áreas/epidemiologia , Alopecia em Áreas/diagnóstico , Criança , Feminino , Masculino , Adolescente , Poder Familiar/psicologia , Depressão/psicologia , Depressão/epidemiologia , Depressão/diagnóstico , Depressão/etiologia , Ansiedade/psicologia , Ansiedade/epidemiologia , Ansiedade/diagnóstico , Ansiedade/etiologia , Pais/psicologia , Estudos de Casos e Controles
9.
Autism ; 28(5): 1297-1304, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38155361

RESUMO

LAY ABSTRACT: It is important to diagnose autism spectrum disorder at an early age and to start an early intervention program without delay. In this study, we aimed to validate the Rapid Interactive Screening Test for Autism in Toddlers (RITA-T) in a group of Turkish children and found that the RITA-T which has been shown to be a valid and reliable screening test for 18- to 36-month-old children in studies conducted in different countries, is also valid in Turkish children. Similar to previous studies, our results showed that the RITA-T has good sensitivity and specificity in distinguishing children with autism spectrum disorder. We think that our study will contribute to the timely initiation of early intervention programs for many children with autism by enabling a valid test to be used in screening programs.


Assuntos
Transtorno do Espectro Autista , Sensibilidade e Especificidade , Humanos , Turquia , Masculino , Pré-Escolar , Feminino , Lactente , Transtorno do Espectro Autista/diagnóstico , Reprodutibilidade dos Testes , Programas de Rastreamento/métodos
10.
Psychiatry ; 86(1): 17-28, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36040868

RESUMO

Objective: Dissociative symptoms are considered risk factors for suicide and non-suicidal self-injury (NSSI). In this study, the relationship between suicidal behaviors and NSSI with dissociative symptoms in adolescents with a history of Child Sexual Abuse (CSA) was investigated. Methods: A total of 100 adolescents with a history of CSA were evaluated with a detailed forensic psychiatric interview. Dissociative symptoms were measured with the self-report Adolescent Dissociative Experiences Scale (A-DES) and the parent-reported Child Dissociative Checklist (CDC). Results: While dissociative symptoms did not differ between adolescents with and without suicide attempts (CDC; p = .068 and A-DES; p = .060), they were significantly higher in adolescents with non-suicidal self-harming behavior (CDC; p < .001 and A-DES; p = .001). Suicide attempts and NSSI were more common in those who reported genital touching as a type of sexual abuse (respectively, p = .003; p = .048). In regression analysis; history of psychiatric treatment (OR = 9.09 [95% CI = 1.52, 54.29]) and NSSI (OR = 8.18 [95% CI = 2.01, 33.23]) were independently associated with suicide attempts. In addition, parent-reported dissociative symptoms (CDC scores) (OR = 1.27 [95% CI = 1.06, 1.53] and suicide attempt (OR = 8.09 [95%CI = 1.96,33.42] showed independent association with NSSI. Conclusions: Dissociative symptoms may be predictive factors for NSSI and should be considered in risk assessment of adolescents with a history of CSA.


Assuntos
Comportamento Autodestrutivo , Delitos Sexuais , Criança , Adolescente , Humanos , Tentativa de Suicídio/psicologia , Comportamento Autodestrutivo/epidemiologia , Comportamento Autodestrutivo/diagnóstico , Comportamento Autodestrutivo/psicologia , Ideação Suicida , Transtornos Dissociativos/epidemiologia , Fatores de Risco
11.
Psychiatry Res Neuroimaging ; 334: 111688, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-37517295

RESUMO

This study aims to examine auditory processing, P300 values and functional impairment levels among children with Attention Deficit and Hyperactivity Disorder (ADHD), Specific Learning Disorder (SLD), ADHD+SLD and healthy controls. Children with ADHD (n = 17), SLD (n = 15), ADHD+SLD (n = 15), and healthy controls (n = 15) between the ages of 7-12 were evaluated with K-SADS, Weiss Functional Impairment Rating Scale, Turgay DSM-IV Disruptive Behavior Disorders Rating Scale, The Mathematics, Reading, Writing Assessment Scale and Children's Auditory Performance Scale (CHAPS). Auditory P300 event-related potentials and Spectral-Temporally Modulated Ripple Test (SMRT) were applied. Three patient groups were found to be riskier than healthy controls according to the CHAPS. There was no significant difference between the groups in the SMRT. In post-hoc analyses of P300 parietal amplitudes, ADHD, SLD, and ADHD+SLD were found to be significantly lower than the control group. The amplitudes of the ADHD+SLD were by far the lowest. It has been shown that auditory performance skills and p300 amplitudes are lower in children diagnosed with only ADHD or SLD compared to the control group, with the lowest values observed in ADHD+SLD. This study suggests that the difficulties with attention and cognitive functions in the ADHD+SLD are more severe than ADHD and/or SLD without comorbidity.


Assuntos
Transtorno do Deficit de Atenção com Hiperatividade , Transtorno de Aprendizagem Específico , Humanos , Criança , Transtorno de Aprendizagem Específico/diagnóstico , Transtorno de Aprendizagem Específico/epidemiologia , Transtorno de Aprendizagem Específico/psicologia , Potenciais Evocados P300 , Cognição , Comorbidade
12.
Agri ; 34(4): 278-291, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-36300749

RESUMO

OBJECTIVES: The aims of this study were to translate the pain catastrophizing scale for children and parents (PCS-C and PCS-P) into Turkish (TurPCS-C and TurPCS-P) and evaluate the psychometric properties in children with primary headache. METHODS: Exploratory factor analysis was used to test the construct validity. Reliability was measured using item-total score correlation, internal consistency (Cronbach α coefficient), Cronbach α if the item was deleted, and test-retest correlation. Concurrent validity and convergent validity of the scales were correlated with other scales (Revised Children's Anxiety and Depression Scale [RCADS], RCADS Parent RCADS-P, Quality of Life Scale for Children [PedsQL], and PedsQL-Parents [PedsQL-P]) and some related features (pain intensity, mobile phone usage time, and headache duration). RESULTS: Of the 80 children participating in the study, 55 (68.8%) were girls and 25 (31.2%) were boys. It was determined that the original three-factor structure was not supported for TurPCS-C and TurPCS-P. Cronbach α value was 0.871 for TurPCS-C consisting of 12 items, and Cronbach α value was 0.890 for TurPCS-P consisting of 12 items. As the PedsQL score increased, there was a negative correlation (p<0.05, r=-0.575) in all three areas of TurPCS-C, and there was a positive correlation (p<0.05) among the scores from the RCADS scale and TurPCS-C. Similarly, there was a negative correlation with PedsQL-P and TurPCS-P and positive correlation with RCADS-P and TurPCS-P (p<0.05 for each). CONCLUSION: TurPCS-C and TurPCS-P are an evaluation instrument with sufficient validity and reliability, and it can be reliably used to examine pediatric patients with primary headache.


Assuntos
Catastrofização , Qualidade de Vida , Masculino , Feminino , Criança , Humanos , Reprodutibilidade dos Testes , Inquéritos e Questionários , Catastrofização/diagnóstico , Psicometria , Pais , Cefaleia/diagnóstico
13.
Turk Psikiyatri Derg ; 32(4): 261-266, 2021.
Artigo em Inglês, Turco | MEDLINE | ID: mdl-34964100

RESUMO

OBJECTIVE: The aim of this study was to demonstrate the validity and reliability of the WFIRS-S-TR, Turkish version of the Weiss Functional Impairment Rating Scale-Self Report form. METHOD: The study comprised two groups of participants of 15-18 years of age, one consisting of 35 children diagnosed with attention deficit and hyperativity disorder (ADHD) based on the DSM-IV criteria and the other, 510 healthy volunteers attending high school. Apart from the WFIRS-S-TR, the Health Questionnaire for Children and Adolescents (KIDSCREEN-10 Index) which is a general quality of life and functionality measurement instrument, was used to check the concurrent validity of the WFIRS-S-TR. RESULTS: The Cronbach's alpha coefficient for the total scale was 0.939. The test-retest reliability assessed by repeated measurements two weeks apart gave a high correlation between the results (r=0.804, p<0.0001). Total mean score of the WFIRS-S-TR showed significant correlation with the KIDSCREEN-10 Index total mean score (r= -0.467, p<0.0001). Confirmatory factor analysis was carried out for the construct validity of the WFIRS-S-TR. The RMSEA and the CFI values were found to be 0.065 and 0.68, respectively. CONCLUSION: The WFIRS-S-TR can be used as a valid and reliable tool both in clinical practice and for research purposes.


Assuntos
Qualidade de Vida , Adolescente , Criança , Humanos , Escalas de Graduação Psiquiátrica , Psicometria , Reprodutibilidade dos Testes , Autorrelato
14.
Int J Soc Psychiatry ; 67(6): 696-704, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-33148091

RESUMO

AIMS: Pandemics can cause substantial psychological distress; however, we do not know the impact of the COVID-19 related lockdown and mental health burden on the parents of school age children. We aimed to comparatively examine the COVID-19 related the stress and psychological burden of the parents with different occupational, locational, and mental health status related backgrounds. METHODS: A large-scale multicenter online survey was completed by the parents (n = 3,278) of children aged 6 to 18 years, parents with different occupational (health care workers-HCW [18.2%] vs. others), geographical (Istanbul [38.2%] vs. others), and psychiatric (child with a mental disorder [37.8%]) backgrounds. RESULTS: Multivariable logistic regression analysis showed that being a HCW parent (odds ratio 1.79, p < .001), a mother (odds ratio 1.67, p < .001), and a younger parent (odds ratio 0.98, p = .012); living with an adult with a chronic physical illness (odds ratio 1.38, p < .001), having an acquaintance diagnosed with COVID-19 (odds ratio 1.22, p = .043), positive psychiatric history (odds ratio 1.29, p < .001), and living with a child with moderate or high emotional distress (odds ratio 1.29, p < .001; vs. odds ratio 2.61, p < .001) were independently associated with significant parental distress. CONCLUSIONS: Parents report significant psychological distress associated with COVID-19 pandemic and further research is needed to investigate its wider impact including on the whole family unit.


Assuntos
COVID-19 , Angústia Psicológica , Adulto , Criança , Controle de Doenças Transmissíveis , Humanos , Pandemias , Pais , SARS-CoV-2 , Estresse Psicológico/epidemiologia , Turquia/epidemiologia
15.
Auris Nasus Larynx ; 46(5): 803-807, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30898404

RESUMO

OBJECTIVE: In this study, we aimed to evaluate the diagnoses of the infants who were admitted to our outpatient clinic with the complaint of pulling on the ear and to identify the related factors which may contribute to the diagnosis. METHODS: This prospective study included a total of 102 infants who were admitted to our hospital with the complaint of tugging and pulling on, touching, and rubbing the ears on the shoulder or pillow and shaking the head between July 2016 and July 2017. The complaints were evaluated throughout the day, and the application seasons, the person referred the patient to the ear, nose, and throat (ENT) specialist, the child development specialist and child psychiatrist, allergy and atopy histories, and the relationship between the results and diagnoses were evaluated. RESULTS: 46.1% of the patients had normal examination findings, while the second most common finding was cerumen in 37.2%, and the third one was otitis media with effusion (OME) in 16.7%. In infants who were directly referred by the family, normal and serological diagnosis were found to be statistically significantly higher than that of OME diagnosis, whereas in the infants referred by the family physicians and pediatrist, the OME was found to be statistically significantly higher than normal and cerumen levels. The presence of additional complaints in the OME group was found to be higher than normal and cerumen group. In those with complaints during the day, the most common finding was OME, while it was cerumen in those with complaints a few times in a day and normal examination finding in those tugging on their ears only, when they were falling asleep, indicating statistical significance. Of 47 infants with normal physical examination findings, 37 were assessed by the child psychiatrist, and depression was found in six of one of the parents during the family interviews. CONCLUSION: In this study, the majority of the infants referred to the ENT outpatient clinic had normal examination findings, while the rate of OME diagnosis was high. Considering the negative consequences of EOM in infants, the diagnosis of the EOM becomes extremely important. If there are no otologic pathologies in the majority of infants who were admitted with ear pulling and tugging, the possibility of different factors in etiology gives rise to thought. Therefore, further studies are required to prove this condition.


Assuntos
Cerume , Orelha , Comportamento do Lactente/fisiologia , Otite Média com Derrame/fisiopatologia , Otopatias , Feminino , Humanos , Lactente , Masculino , Otite Média com Derrame/diagnóstico , Pediatras , Médicos de Família , Estudos Prospectivos , Encaminhamento e Consulta , Estações do Ano
16.
Breastfeed Med ; 14(1): 57-62, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30412418

RESUMO

OBJECTIVE: The aim of the present study is to investigate the duration of breastfeeding in relation to various parafunctional oral habits in children with anxiety disorders. MATERIALS AND METHODS: The study includes 195 children and adolescents with anxiety disorders and age- and gender-matched 255 healthy control subjects. Diagnoses were made with semistructured interview (K-SADS). Information about breastfeeding and parafunctional oral habits was investigated via a questionnaire prepared for the study. RESULTS: The mean age was 11.50 ± 2.50 years for clinical group and 11.27 ± 2.33 years for controls. Fifty-four percent of the clinical group and 56% of the control group were female subjects. Duration of exclusive (4.72 ± 2.86, 5.55 ± 2.36; p = 0.002) and total breastfeeding (12.38 ± 10.32, 15.89 ± 9.09; p < 0.001) was significantly lower and duration of bottle-feeding (22.30 ± 19.54, 16.64 ± 12.79; p = 0.005) was higher than controls in the clinical group. Duration of exclusive breastfeeding was significantly correlated with duration of bottle-feeding (r = -0.263, p < 0.001) and duration of pacifier use (r = -0.249, p = 0.001). Multiple regression analysis showed that duration of exclusive breastfeeding (ß = 0.88, p = 0.006) and bottle-feeding (ß = 1.02, p = 0.005), as well as various oral habits, was associated with diagnosis of an anxiety disorder. CONCLUSION: Nutrition methods in early years of life may result in long-term consequences regarding anxiety disorders for children. Clinicians should encourage parents for a shorter duration of bottle-feeding and a longer duration of exclusive breastfeeding.


Assuntos
Transtornos de Ansiedade/epidemiologia , Alimentação com Mamadeira/efeitos adversos , Aleitamento Materno , Sucção de Dedo , Hábito de Roer Unhas , Chupetas/efeitos adversos , Adolescente , Bruxismo/epidemiologia , Estudos de Casos e Controles , Criança , Feminino , Humanos , Lactente , Recém-Nascido , Modelos Logísticos , Masculino , Escalas de Graduação Psiquiátrica , Ronco/epidemiologia , Inquéritos e Questionários , Fatores de Tempo , Turquia/epidemiologia
17.
Noro Psikiyatr Ars ; 55(1): 54-58, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30042642

RESUMO

INTRODUCTION: The aim of the study is to investigate the relationship between circadian characteristics and behavioral problems in children with Attention Deficit Hyperactivity Disorder (ADHD) (n=53), and to compare this group with healthy controls (n=38). METHOD: Fifty-three medication-free children with ADHD, aged 6-12 years, and 38 healthy children, age and sex matched, participated. Parents completed the Conners' Parent Rating Scale-Revised, the Children's Chronotype Questionnaire (CCTQ), and the Children's Sleep Habits Questionnaire (CSHQ) to assess sleep variables. RESULTS: ADHD children had more sleep-onset problems and parasomnias (in CSHQ) compared to healthy controls. However, circadian preferences did not differ between the groups in CCTQ scores. Another important finding was a mild correlation between parasomnia, bedtime on schooldays, and ADHD symptoms. CONCLUSION: Our study showed that children with ADHD showed more resistance to going to bed than did controls on school days. However, in contrast to our hypothesis, morningness/eveningness preference did not differ from controls in ADHD children.

18.
Noro Psikiyatr Ars ; 54(3): 267-271, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-29033641

RESUMO

INTRODUCTION: The mechanism of ubiquitination-related abnormalities causing neural development problems is still unclear. We examined the association between autism and serum transactive response DNA-binding protein-43 (TDP-43) and ubiquitin c-terminal hydrolase-L1 (UCH-L1) levels, both of which are members of the ubiquitin-proteosome system. METHODS: We measured serum levels of TDP-43 and UCH-L1 in 24 children with autism and 24 healthy children. Childhood Autism Rating Scale (CARS) was used to assess symptom severity at admission. RESULTS: The mean serum TDP-43 and UCH-L1 levels in children with autism spectrum disorder (ASD) were found to decrease compared to healthy controls (p<0.001, 506.21±780.97 ng/L and 1245.80±996.76 ng/L, respectively; 3.08±5.44 ng/mL and 8.64±6.67 ng/mL, respectively). A positive correlation between serum TDP-43 levels and UCH-L1 levels was found in the ASD group (r=0.947, n=24, p<0.001). The CARS score of children with ASD was 48.91 points (standard deviation [SD]: 5.82). CONCLUSION: Low serum levels of UCH-L1 and TDP-43 may reflect disturbed ubiquitination in autism.

20.
Turk Psikiyatri Derg ; 26(2): 87-98, 2015.
Artigo em Turco | MEDLINE | ID: mdl-26111284

RESUMO

OBJECTIVE: The aim of this study is to evaluate the relationship between postpartum depression (PPD), infantile colic (IC) and different psychosocial variables, psychiatric symptoms, attachment style and perceived social support in expecting parents. METHOD: Two hundred forty five expecting mothers and 150 expecting fathers were first interviewed between the 22-34 weeks of pregnancy. Sociodemografic data form, Adult Attachment Style Scale (AASS), State Anxiety Inventory (SAI), Edinburgh Postnatal Depression Scale (EPDS), Multidimensional Scale of Perceived Social Support (MSPSS) and Brief Symptom Inventory (BSI) were filled out by each expecting parent. Second interview was conducted between the postpartum 4-24 weeks. Data form consisting health, nutrition, sleep and crying problems of the infant and EPDS and SAI were filled out by mothers and SAI by fathers. RESULTS: One in every four mothers had PPD symptoms above the threshold on EPDS. Maternal and paternal insecure attachment style, maternal psychiatric symptoms and postpartum anxiety level were found to be the predictors of PPD. One in every five infants had IC and maternal education level, hostility score and PPD symptoms along with paternal insecure attachment style and psychiatric symptoms were the main predictors of IC. CONCLUSION: Results about PPD and IC regarding maternal variables are consistent with the literature. In addition, paternal insecure attachment style is found to be an important risk factor for both PPD and IC. Fathers should also be included in further studies exploring PPD or IC.


Assuntos
Cólica , Depressão Pós-Parto/psicologia , Relações Mãe-Filho , Mães/psicologia , Adolescente , Adulto , Feminino , Seguimentos , Humanos , Recém-Nascido , Masculino , Gravidez , Escalas de Graduação Psiquiátrica , Turquia , Adulto Jovem
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