[Evaluation of the action « M'T Dents ¼ for 6-year-old schoolchildren on two deprived neighborhoods in Marseille, France]. / Evaluation de l'action « M'T dents ¼ auprès des enfants de 6 ans scolarisés sur deux quartiers défavorisés à Marseille.

Background: This study aims to analyze the effects of the national program for individual dental prevention "M'T Dents" to 6-years-old children living in the neighborhoods of deprived areas Saint-Mauront and Belle de Mai from 2009 to 2012 (Marseille, France). These children having received an additional collective awareness and individual monitoring as part of the experimental program of health promotion "La Santé à Saint Mauront - Belle de Mai: on s'y met tous!" led by the PACA Regional Health Agency. Materials and Methods: Awareness sessions in oral hygiene were led in CP grades of 5 schools and each child was then followed and encouraged to resort to dentist. Data on the use of the bucco-dental examination (BDE), the use of consecutive care and the oral health status of children were collected. Results: Of the three years considered by this study, 56 classes and more than 1000 children were involved by this prevention program. The average use of BDE was 27.70%. Among children who received the BDE, 44.33% required treatment, approximately 26% with 1-3 untreated caries, 12%: 4-6 caries and 6%: 7 caries or more. Nearly 60% were completely cured, 15% partially and 25% not treated within 6 months following the BDE. Care utilization varied by initial caries index: the percentage of children fully treated was significantly higher for children with 1-3 caries than those with 4-6 caries (p <0.05) and those with 7 caries or more (p < 0.001) when the BDE. Conclusion: Modes of action that are reinforced in this territory seem possible to achieve results comparable to those observed in the same age group at the national level for children. More children were able to use the dentist and receive consecutive care under this program contributes to reducing inequalities in oral health.

[Study of remains and dental wastes of a First World War German rest camp]. / Etude des restes et déchets dentaires d'un camp de repos allemand de la première guerre mondiale.

INTRODUCTION: This article presents the analysis of dental remains and waste from the dental office of a German rest camp of the First World War in order to study the living conditions of the soldiers, the care policy and the prosthetic rehabilitation techniques used in this context. MATERIALS AND METHODS: The study included both dental and prosthetic remains, revealed during the excavation. The criteria to determine dental and periodontal health were the presence or absence of caries, wear, tartar and periodontal lesion. Location, severity and frequency of each of these parameters were examined. Regarding the prosthetic remains, the type of prosthesis and the materials used were determined. RESULTS: Three hundred and twenty seven (327) dental remains were analyzed. A high prevalence of large caries, especially in the molar areas, was highlighted. The incisal areas had however more wear and tartar. 183 casts of plaster dental arcade allowed to highlight a significant proportion of posterior edentulous. Prosthetic remains and laboratory waste revealed the use of vulcanite and porcelain for making dentures.

[Relationship between menopause and tooth loss]. / Période de la ménopause, mortalité dentaire et facteurs systémiques.

This work proposes to evaluate the relationship between menopause and oral health by a cross-sectional study conducted on 202 menopausal women with or without hormone replacement therapy (HRT) and not menopausal women, with backgrounds socio-economic and socio-cultural variety and aged 42 to 80 years. Two hundred and two patients were the subject of an interrogation and a detailed clinical examination. Relations between menopausal and dental mortality were determined by bi and multi analyses varied. The result notes that the number of missing teeth is lowest among women from backgrounds socio - economic favored (p = 0.015). In addition, the number of missing teeth is highly correlated with dry mouth (p = 0,000). On the other hand, postmenopausal women on hormone replacement therapy have less missing teeth than postmenopausal women without hormone replacement therapy, (p = 0.02). In addition, the number of missing teeth is significantly increased in non-diabetic heart women, (OR = 1,215). This result is essentially the same in heart patient, non-diabetic postmenopausal patients without HRT, (OR = 1,214). Finally, we note a link between stressful events and dental mortality (p = 0.042).

3D CT scan study of fetal cranial base: interests of occipital bone measurements in age estimation.

OBJECTIVES: Cranial base development during fetal life is of major interest for many research purposes. In this study, we focused on fetal age estimations which are extremely important in forensic contexts. Nevertheless, there have been very few studies using occipital measurements to determine fetal age. OBJECTIVES: To evaluate change in the sagittal length/maximum width ratio of the basilar part of the occipital bone and to propose a simple and reliable method for fetal age determination. METHODS: A sample of 30 male and 7 female fetuses aged 24 to 41 weeks amenorrhea underwent CT scan. Occipital bones were reconstructed (Amira 4.0) and measurements were carried out on each part. RESULTS: A multivariate analysis (ANOVA) gave an age formula using right exoccipital measurements and a linear regression supplied the age of reversion of the sagittal length/maximum width ratio. CONCLUSION: This preliminary study clearly highlighted the promises of 3D CT-Scan studies of fetal cranial base and gave interesting results and the method deserves to be tested on a larger sample.

Antibacterial efficiency of passive ultrasonic versus sonic irrigation. Ultrasonic root canal irrigation.

OBJECTIVES: To compare the antibacterial effect of the passive ultrasonic to passive sonic irrigation with a 5.25% NaOCI solution. METHODS: Sixty human teeth were used. The crowns were removed and the roots were instrumented prior to sterilization and incubation with Enterococcus faecalis. Five mL of 5.25% NaOCI were used during a 3 min final rinsing with: syringe irrigation (n = 20), passive ultrasonic irrigation with the Irrisafe (n = 20) and passive sonic irrigation with the Endo Activator (n = 20). A sterile file was used to remove dentine shavings at the apex and placed in BHI. After 72 h, this infusion was used to inoculate blood agar plates. The presence or absence of Enterococcus faecalis colonies was determined and statistically analyzed. RESULTS: No statistically significant difference was found among the 3 groups. None of the irrigation regimen permitted to obtain 100% of bacteria free teeth. CONCLUSION: The passive agitation of the irrigation solution did not increase its antibacterial efficiency. Longer irrigation times may be required.

[Correlation between the position of the 1st molars and the 3-dimensional trajectory of anterior guidance]. / Etude de la corrélation entre la mise en place des premières molaires et les trajectoires tridimensionnelles du guide antérieur.

This study tries to demonstrate that there is a correlation between the anterior trajectories of the mandible, in the anterior-posterior and lateral directions, and the occlusal morphology of the first permanent molars. The clinical consequences are interesting for prosthetic treatments, in the rehabilitation of anterior and canine guidance, and for orthodontic treatments.

Characteristics and prediction of the alveolar bone loss: essay of modeling.

The alveolar bone loss is a phenomenon which intervenes throughout the life and which can be aggravated by the action of individual and behavioural factors. From this observation we shall try to characterize it and to propose formulas of prediction of the alveolar bone loss according to the age of the patient. We shall expose an analysis of factors bound to the alveolar bone loss and propose a modeling of the alveolar bone loss according to the age in an essentially predictive purpose. The methodology is based on the medical exploitation of CT-dentascanners and medical questionnaire as well as administrative questionnaire used in odontology. Measures of the distance ECJ and the summit of crest are made on the radiology and the individual factors and behavioural factors are scored. The descriptive analysis of the data allowed us to characterize the phenomenon of alveolar bone loss in a therapeutic purpose. The statistical treatment of these data will establish various models according to gender. The described method is simple and its applications seem numerous in the several domains: prevention, improvement of prosthetic and periodontal therapeutics.

Extracorporeal lithotripsy of salivary gland stone: A 55 patients study.

Sialolithiasis are the most frequent salivary gland disease, mainly affecting the submandibular gland. With the advent of minimally invasive techniques, total salivary gland removal should not be considered as the first-line treatment anymore. Extracorporeal Shock Wave Lithotripsy (ESWL) is an alternative to surgery preserving the gland. The objective of our retrospective study was to evaluate the efficiency of ESWL on pain and obstructive syndrome in patients suffering from sialolithiasis. The global result felt by the patients was also considered. All patients treated between October 2009 and July 2016 for sialolithiasis by ESWL in our department were included. They were divided into two groups according to the concerned gland: a parotid gland (PG) and a submandibular gland (SMG) group. Our retrospective telephone questionnaire consisted in 4 questions about their symptomatology before and after ESWL, including pain self-evaluation before and after treatment. They were finally asked to evaluate the global result of the ESWL treatment: excellent, good, mean, or poor. In total, 55 patients were included in this study, 38 patients in PG group and 17 patients in SMG group. We observed a decrease of pain and obstructive syndrom after ESWL procedure in both groups. Better results were found on the obstructive syndrome in the PG group. Very few side-effects were reported by patients. Given that it has very few side effects, ESWL can easily be considered as first line treatment for sialolithiasis to avoid heavier treatments such as surgery. It should be the first-line treatment for symptomatic parotid sialolithiases. The treatment of symptomatic submandibular sialolithiases depends on the topography of the lithiasis.

Laboratory Studies of Nonlinear Optical Signals for Caries Detection.

Multiphoton confocal microscopy and nonlinear spectroscopy are used to investigate the caries process in dentin. Although dentin is a major calcified tissue of the teeth, its organic phase comprises type I collagen fibers. Caries drive dentin demineralization and collagen denaturation. Multiphoton microscopy is a powerful imaging technique: the biological materials are transparent to infrared frequencies and can be excited to penetration depths inaccessible to 1-photon confocal microscopy. The laser excitation greatly reduces photodamage to the sole focal region, and the signal-to-noise ratio is improved significantly. The method has been used to follow pathologic processes involving collagen fibrosis or collagen destruction based on their 2-photon excited fluorescence (2PEF) emission and second harmonic generation (SHG). Combining multiphoton imaging with nonlinear spectroscopy, we demonstrate that both 2PEF and SHG intensity of human dentin are strongly modified during the tooth caries process, and we show that the ratio between SHG and 2PEF signals is a reliable parameter to follow dental caries. The ratio of the SHG/2PEF signals measured by nonlinear optical spectroscopy provides valuable information on the caries process, specifically on the degradation of the organic matrix of dentin. The goal is to bring these nonlinear optical signals to clinical application for caries diagnosis.

Dietary level of protein regulates glyceraldehyde-3-phosphate dehydrogenase content and synthesis rate in mouse liver cytosol.

The content of liver cytosolic proteins was studied in mice subjected to protein depletion followed by refeeding with a normal diet. Depletion elicited either the accumulation or the decrease of several polypeptides, being the early increase of a M(r) 36,000 polypeptide the most pronounced change observed. The refeeding with a normal diet for 2 days caused a return of the cytosol protein composition to that of normally fed animals. The M(r) 36,000 polypeptide was identified as glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Its molecular weight, the sequence of its first twenty amino acid residues, its amino acid composition and its antigenic properties were found to be similar with those of GAPDH from different mammalian cells. During the first 2 days of protein depletion, both the GAPDH polypeptide content and activity increased. Thereafter, the enzymatic activity of GAPDH decreased, whereas GAPDH protein mass decreased in a lesser extent. The accumulation of GAPDH and other particular polypeptides in the cytosols of protein depleted mice was associated with an increased synthesis. The refeeding with a normal diet caused an immediate return to the synthesis pattern of normal livers.