Detalhe da pesquisa
1.
Validation of LC-MS/MS methods for determination of remdesivir and its metabolites GS-441524 and GS-704277 in acidified human plasma and their application in COVID-19 related clinical studies.
Anal Biochem
; 617: 114118, 2021 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33508271
2.
An LC-MS/MS method for determination of tenofovir (TFV) in human plasma following tenofovir alafenamide (TAF) administration: Development, validation, cross-validation, and use of formic acid as plasma TFV stabilizer.
Anal Biochem
; 593: 113611, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32035040
3.
The determination of human peripheral blood mononuclear cell counts using a genomic DNA standard and application in tenofovir diphosphate quantitation.
Anal Biochem
; 585: 113399, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31437427
4.
Phase 1 first-in-human study of dalutrafusp alfa, an anti-CD73-TGF-ß-trap bifunctional antibody, in patients with advanced solid tumors.
J Immunother Cancer
; 11(2)2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36746510
5.
Plasma Protein Binding Determination for Unstable Ester Prodrugs: Remdesivir and Tenofovir Alafenamide.
J Pharm Sci
; 112(12): 3224-3232, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37722451
6.
Evaluation of the potential for pharmacokinetic interaction between tirabrutinib and levonorgestrel/ethinyl estradiol in healthy female volunteers.
Clin Transl Sci
; 15(6): 1492-1499, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35266297
7.
Assessment of the Effect of Filgotinib on the Pharmacokinetics of Atorvastatin, Pravastatin, and Rosuvastatin in Healthy Adult Participants.
Clin Pharmacol Drug Dev
; 11(2): 235-245, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34468080
8.
The determination of Sulfobutylether ß-Cyclodextrin Sodium (SBECD) by LC-MS/MS and its application in remdesivir pharmacokinetics study for pediatric patients.
J Pharm Biomed Anal
; 212: 114646, 2022 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35180564
9.
Semi-Mechanistic PK/PD Modeling and Simulation of Irreversible BTK Inhibition to Support Dose Selection of Tirabrutinib in Subjects with RA.
Clin Pharmacol Ther
; 111(2): 416-424, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34623640
10.
Pharmacokinetics and Safety of Momelotinib in Subjects With Hepatic or Renal Impairment.
J Clin Pharmacol
; 58(4): 522-532, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29283448
11.
Quantitation of intracellular triphosphate metabolites of antiretroviral agents in peripheral blood mononuclear cells (PBMCs) and corresponding cell count determinations: review of current methods and challenges.
Expert Opin Drug Metab Toxicol
; 14(8): 781-802, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-30010446
12.
The Relative Bioavailability, Food Effect, and Drug Interaction With Omeprazole of Momelotinib Tablet Formulation in Healthy Subjects.
Clin Pharmacol Drug Dev
; 7(3): 277-286, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29024542