Detalhe da pesquisa
1.
Chatterboxes: the structural and functional diversity of cyclins.
Semin Cell Dev Biol
; 107: 4-20, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32414682
2.
Probing biological activity through structural modelling of ligand-receptor interactions of 2,4-disubstituted thiazole retinoids.
Bioorg Med Chem
; 26(8): 1560-1572, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29439915
3.
New active leads for tuberculosis booster drugs by structure-based drug discovery.
Org Biomol Chem
; 15(48): 10245-10255, 2017 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29182187
4.
Structural and docking studies of potent ethionamide boosters.
Acta Crystallogr C
; 69(Pt 11): 1243-50, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24192167
5.
Crystallographic fragment screening in academic cancer drug discovery.
Methods Enzymol
; 690: 211-234, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37858530
6.
An open-source molecular builder and free energy preparation workflow.
Commun Chem
; 5(1): 136, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36320862
7.
Targeting Mre11 overcomes platinum resistance and induces synthetic lethality in XRCC1 deficient epithelial ovarian cancers.
NPJ Precis Oncol
; 6(1): 51, 2022 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35853939
8.
FEN1 Blockade for Platinum Chemo-Sensitization and Synthetic Lethality in Epithelial Ovarian Cancers.
Cancers (Basel)
; 13(8)2021 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33919707
9.
Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation.
J Mol Biol
; 433(5): 166795, 2021 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33422522
10.
Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors.
Nat Commun
; 11(1): 1383, 2020 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32170057
11.
The diverse structural landscape of quadruplexes.
FEBS Lett
; 593(16): 2083-2102, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31325371
12.
Relative Binding Energies Predict Crystallographic Binding Modes of Ethionamide Booster Lead Compounds.
J Phys Chem Lett
; 10(9): 2244-2249, 2019 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30965004
13.
Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition.
Cell Chem Biol
; 26(1): 121-130.e5, 2019 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30472117