Detalhe da pesquisa
1.
IRGM1 links mitochondrial quality control to autoimmunity.
Nat Immunol
; 22(3): 312-321, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33510463
2.
The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy.
Mol Cell
; 73(3): 429-445.e7, 2019 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30612879
3.
Which Types of Stress Are Associated With Accelerated Biological Aging? Comparing Perceived Stress, Stressful Life Events, Childhood Adversity, and Posttraumatic Stress Disorder.
Psychosom Med
; 85(5): 389-396, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37053097
4.
Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5.
PLoS Pathog
; 16(8): e1008327, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32853276
5.
Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium.
PLoS Pathog
; 16(5): e1008553, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32453761
6.
Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock.
EMBO Rep
; 21(11): e50830, 2020 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33124745
7.
Murine Irgm Paralogs Regulate Nonredundant Functions To Execute Host Defense to Toxoplasma gondii.
Infect Immun
; 89(11): e0020221, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34338548
8.
Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages.
J Biol Chem
; 292(11): 4651-4662, 2017 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28154172
9.
IRGM3 contributes to immunopathology and is required for differentiation of antigen-specific effector CD8+ T cells in experimental cerebral malaria.
Infect Immun
; 83(4): 1406-17, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25644000
10.
IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins.
PLoS Pathog
; 9(6): e1003414, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23785284
11.
Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-γ-induced mouse cells.
J Immunol
; 191(4): 1765-74, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23842753
12.
IFN-γ-induced macrophage antileishmanial mechanisms in mice: A role for immunity-related GTPases, Irgm1 and Irgm3, in Leishmania donovani infection in the liver.
Exp Parasitol
; 157: 103-9, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26208780
13.
p47 GTPases: regulators of immunity to intracellular pathogens.
Nat Rev Immunol
; 4(2): 100-9, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15040583
14.
The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18.
PLoS Pathog
; 8(11): e1002992, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23144612
15.
Discovery of a novel Toxoplasma gondii conoid-associated protein important for parasite resistance to reactive nitrogen intermediates.
J Immunol
; 188(7): 3404-15, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22387554
16.
Irgm proteins attenuate inflammatory disease in mouse models of genital Chlamydia infection.
mBio
; 15(4): e0030324, 2024 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38501887
17.
Posttraumatic stress disorder, trauma, and accelerated biological aging among post-9/11 veterans.
Transl Psychiatry
; 14(1): 4, 2024 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38184702
18.
Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation.
Am J Physiol Gastrointest Liver Physiol
; 305(8): G573-84, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23989005
19.
Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections.
PLoS Pathog
; 7(6): e1001346, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21731484
20.
Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling.
Blood
; 118(6): 1525-33, 2011 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21633090