Detalhe da pesquisa
1.
Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site.
Cell
; 137(2): 332-43, 2009 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19379698
2.
MRP4 Modulation of the Guanylate Cyclase-C/cGMP Pathway: Effects on Linaclotide-Induced Electrolyte Secretion and cGMP Efflux.
J Pharmacol Exp Ther
; 355(1): 48-56, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26216942
3.
Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells.
Proc Natl Acad Sci U S A
; 107(51): 22255-9, 2010 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21139054
4.
Olinciguat, a stimulator of soluble guanylyl cyclase, attenuates inflammation, vaso-occlusion and nephropathy in mouse models of sickle cell disease.
Br J Pharmacol
; 178(17): 3463-3475, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33864386
5.
Olinciguat, an Oral sGC Stimulator, Exhibits Diverse Pharmacology Across Preclinical Models of Cardiovascular, Metabolic, Renal, and Inflammatory Disease.
Front Pharmacol
; 11: 419, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32322204
6.
Peritoneal macrophages express both P-selectin and PSGL-1.
J Cell Biol
; 163(5): 1145-55, 2003 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-14662752
7.
Characterization of the novel P-selectin inhibitor PSI-697 [2-(4-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h] quinoline-4-carboxylic acid] in vitro and in rodent models of vascular inflammation and thrombosis.
J Pharmacol Exp Ther
; 324(2): 497-506, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18024786
8.
Epitope identification of specific naturally occurring human anti-avidin antibodies.
Immunol Lett
; 196: 119-123, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29175317
9.
The von Willebrand factor antagonist (GPG-290) prevents coronary thrombosis without prolongation of bleeding time.
Thromb Haemost
; 98(2): 397-405, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17721623
10.
Linaclotide activates guanylate cyclase-C/cGMP/protein kinase-II-dependent trafficking of CFTR in the intestine.
Physiol Rep
; 5(11)2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28592587
11.
Guanylate cyclase-C/cGMP: an emerging pathway in the regulation of visceral pain.
Front Mol Neurosci
; 7: 31, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24795564
12.
Gastrointestinal pain: unraveling a novel endogenous pathway through uroguanylin/guanylate cyclase-C/cGMP activation.
Pain
; 154(9): 1820-1830, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23748116
13.
Pharmacology, biodistribution, and efficacy of GPCR-based pepducins in disease models.
Methods Mol Biol
; 683: 259-75, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21053136
14.
Discovery of 2-[1-(4-chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid (PSI-421), a P-selectin inhibitor with improved pharmacokinetic properties and oral efficacy in models of vascular injury.
J Med Chem
; 53(16): 6003-17, 2010 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20718494
15.
SLIC-1/sorting nexin 20: a novel sorting nexin that directs subcellular distribution of PSGL-1.
Eur J Immunol
; 38(2): 550-64, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18196517