Detalhe da pesquisa
1.
In vivo efficacy of apramycin in murine infection models.
Antimicrob Agents Chemother
; 58(11): 6938-41, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25136009
2.
Pharmacokinetic and pharmacodynamic evaluation of the atypical tetracyclines chelocardin and amidochelocardin in murine infection models.
Microbiol Spectr
; 12(1): e0128923, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38047701
3.
Studies of antibacterial activity (in vitro and in vivo) and mode of action for des-acyl tridecaptins (DATs).
Eur J Med Chem
; 265: 116097, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38157595
4.
Discovery, optimisation and in vivo evaluation of novel GPR119 agonists.
Bioorg Med Chem Lett
; 21(24): 7310-6, 2011 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22061639
5.
Prolonged inhibition of glycogen phosphorylase in livers of Zucker Diabetic Fatty rats models human glycogen storage diseases.
Toxicol Pathol
; 38(3): 393-401, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20215584
6.
Glucagon challenge in the rat: a robust method for the in vivo assessment of Glycogen phosphorlyase inhibitor efficacy.
J Pharmacol Toxicol Methods
; 55(1): 71-7, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-16713718
7.
Bioanalysis of Pseudomonas aeruginosa alkyl quinolone signalling molecules in infected mouse tissue using LC-MS/MS; and its application to a pharmacodynamic evaluation of MvfR inhibition.
J Pharm Biomed Anal
; 139: 44-53, 2017 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28273650
8.
Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats.
Diabetes
; 51(8): 2441-9, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12145156
9.
Circumventing seizure activity in a series of G protein coupled receptor 119 (GPR119) agonists.
J Med Chem
; 57(21): 8984-98, 2014 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25286150
10.
Use of small-molecule crystal structures to address solubility in a novel series of G protein coupled receptor 119 agonists: optimization of a lead and in vivo evaluation.
J Med Chem
; 55(11): 5361-79, 2012 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22545772
11.
Reversibility of hyperglycaemia and islet abnormalities in the high fat-fed female ZDF rat model of type 2 diabetes.
J Pharmacol Toxicol Methods
; 63(1): 15-23, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-20398780