Detalhe da pesquisa
1.
In vivo activity of the dual PI3Kδ and PI3Kγ inhibitor duvelisib against pediatric acute lymphoblastic leukemia xenografts.
Pediatr Blood Cancer
; 70(8): e30398, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37140091
2.
In vivo activity of the dual SYK/FLT3 inhibitor TAK-659 against pediatric acute lymphoblastic leukemia xenografts.
Pediatr Blood Cancer
; : e30503, 2023 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37339930
3.
In vivo evaluation of the lysine-specific demethylase (KDM1A/LSD1) inhibitor SP-2577 (Seclidemstat) against pediatric sarcoma preclinical models: A report from the Pediatric Preclinical Testing Consortium (PPTC).
Pediatr Blood Cancer
; 68(11): e29304, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34453478
4.
Preclinical evaluation of the combination of AZD1775 and irinotecan against selected pediatric solid tumors: A Pediatric Preclinical Testing Consortium report.
Pediatr Blood Cancer
; 67(5): e28098, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31975571
5.
Antibody-drug conjugates for cancer therapy.
Lancet Oncol
; 17(6): e254-e262, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27299281
6.
Antibody drug conjugates.
Curr Opin Oncol
; 26(5): 476-83, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25024051
7.
In vivo activity of the second-generation proteasome inhibitor ixazomib against pediatric T-cell acute lymphoblastic leukemia xenografts.
Exp Hematol
; 132: 104176, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38320689
8.
Multicellular Complex Tumor Spheroid Response to DNA Repair Inhibitors in Combination with DNA-damaging Drugs.
Cancer Res Commun
; 3(8): 1648-1661, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37637936
9.
Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems-based Resource.
Mol Cancer Ther
; 22(11): 1270-1279, 2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37550087
10.
Testing of the topoisomerase 1 inhibitor Genz-644282 by the pediatric preclinical testing program.
Pediatr Blood Cancer
; 58(2): 200-9, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21548007
11.
Antibody-drug Conjugate Targets, Drugs, and Linkers.
Curr Cancer Drug Targets
; 22(6): 463-529, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35209819
12.
Integrative epigenomic analyses of small cell lung cancer cells demonstrates the clinical translational relevance of gene body methylation.
iScience
; 25(11): 105338, 2022 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36325065
13.
Trastuzumab Deruxtecan, Antibody-Drug Conjugate Targeting HER2, Is Effective in Pediatric Malignancies: A Report by the Pediatric Preclinical Testing Consortium.
Mol Cancer Ther
; 21(8): 1318-1325, 2022 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35657346
14.
Evaluation of the DLL3-targeting antibody-drug conjugate rovalpituzumab tesirine in preclinical models of neuroblastoma.
Cancer Res Commun
; 2(7): 616-623, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36381237
15.
Tumor endothelial marker 7 (TEM-7): a novel target for antiangiogenic therapy.
Microvasc Res
; 82(3): 253-62, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21958527
16.
Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence.
Exp Cell Res
; 316(2): 258-71, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19732767
17.
TGFß-Directed Therapeutics: 2020.
Pharmacol Ther
; 217: 107666, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32835827
18.
Format (2D vs 3D) and media effect target expression and response of patient-derived and standard NSCLC lines to EGFR inhibitors.
Cancer Treat Res Commun
; 29: 100463, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34601320
19.
Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine.
SLAS Discov
; 26(10): 1298-1314, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34772287
20.
Association of expression of epigenetic molecular factors with DNA methylation and sensitivity to chemotherapeutic agents in cancer cell lines.
Clin Epigenetics
; 13(1): 49, 2021 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33676569