Detection of envelope modulation and direction of arrival estimation of multiple noise sources with an acoustic vector sensor.

The Detection of Envelope Modulation on Noise (DEMON) is an algorithm that is commonly applied to hydrophone data for the detection and classification of underwater noise produced by a ship. This algorithm utilizes modulation analysis to determine the frequencies that modulate the broadband cavitation noise produced by marine vessel propellers. In this paper, a DEMON demodulator for acoustic vector sensors (AVSs) that are directional hydrophones capable of acquiring both the acoustic pressure and the components of the particle velocity vector is defined. The proposed method is able to extract multiple modulating signals and measure their direction of arrival. The proposed receiver was validated with real data collected at sea with a moving buoyancy glider hosting an AVS.

Tracking of multiple surface vessels based on passive acoustic underwater arrays.

This paper introduces an approach to localize and track an unknown number of non-cooperative surface vessels based on passive acoustic sensing of their noise radiated underwater. Time-Difference of Arrival (TDOA) measurements are extracted from pairs of hydrophones, and a recently introduced Bayesian framework for multi-object tracking is employed to detect and track vessels from TDOA measurements. Results based on data from a three-dimensional compact hydrophone array towed by an autonomous vehicle confirm that non-cooperative surface vessels can be detected and tracked.

Behavioral and cognitive effects of docosahexaenoic acid in drug-naïve children with attention-deficit/hyperactivity disorder: a randomized, placebo-controlled clinical trial.

This study aimed to investigate the efficacy of docosahexaenoic acid (DHA) dietary supplementation on behavior and cognition in school-aged, drug-naïve children with attention-deficit/hyperactivity disorder (ADHD). A total of 50 participants with ADHD aged 7 to 14 were enrolled in a 6-month randomized, placebo-controlled clinical trial and received either DHA or placebo. The primary outcome measure was the change in the ADHD rating scale IV Parent Version-Investigator (ADHD-RS-IV) after 4 and 6 months. Secondary outcome measures included Conners Parent Rating Scale-revised, other behavioral rating scales including quality of life and global functioning, and computerized cognitive tasks. Baseline assessment also addressed the blood fatty acids profile. No superiority of DHA supplement to placebo was observed on ADHD-RS-IV, the a priori primary outcome. DHA supplementation showed a significant, nonetheless quite small, effect on children's psychosocial functioning, emotional problems, and focused attention. Neither major nor minor adverse events were reported throughout the trial. This study shows that 6-month DHA supplementation has no beneficial effect on the symptoms of ADHD in school-aged, drug-naïve children with an established diagnosis of ADHD. Nevertheless, the 6 months treatment with supplemental DHA appears to have small positive effects on other behavioral and cognitive difficulties, which, in light of the absence of side-effects, could be reasonably followed up in future intervention studies. ( https://clinicaltrials.gov/ct2/show/NCT01796262 : The Effects of DHA on Attention Deficit and Hyperactivity Disorder (DADA)).

The potential relevance of docosahexaenoic acid and eicosapentaenoic acid to the etiopathogenesis of childhood neuropsychiatric disorders.

Over the last 15 years, considerable interest has been given to the potential role of omega-3 polyunsaturated fatty acids (PUFAs) for understanding pathogenesis and treatment of neurodevelopmental and psychiatric disorders. This review aims to systematically investigate the scientific evidence supporting the hypothesis on the omega-3 PUFAs deficit as a risk factor shared by different pediatric neuropsychiatric disorders. Medline PubMed database was searched for studies examining blood docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA) status in children with neuropsychiatric disorders. Forty-one published manuscripts were compatible with the search criteria. The majority of studies on attention-deficit/hyperactivity disorder (ADHD) and autism found a significant decrease in DHA levels in patients versus healthy controls. For the other conditions examined-depression, juvenile bipolar disorder, intellectual disabilities, learning difficulties, and eating disorders (EDs)-the literature was too limited to draw any stable conclusions. However, except EDs, findings in these conditions were in line with results from ADHD and autism studies. Results about EPA levels were too inconsistent to conclude that EPA could be associated with any of the conditions examined. Finally, correlational data provided, on one hand, evidence for a negative association between DHA and symptomatology, whereas on the other hand, evidence for a positive association between EPA and emotional well-being. Although the present review underlines the potential involvement of omega-3 PUFAs in the predisposition to childhood neuropsychiatric disorders, more observational and intervention studies across different diagnoses are needed, which should integrate the collection of baseline PUFA levels with their potential genetic and environmental influencing factors.

Latent classes of emotional and behavioural problems in epidemiological and referred samples and their relations to DSM-IV diagnoses.

Researchers' interest have recently moved toward the identification of recurrent psychopathological profiles characterized by concurrent elevations on different behavioural and emotional traits. This new strategy turned to be useful in terms of diagnosis and outcome prediction. We used a person-centred statistical approach to examine whether different groups could be identified in a referred sample and in a general-population sample of children and adolescents, and we investigated their relation to DSM-IV diagnoses. A latent class analysis (LCA) was performed on the Child Behaviour Checklist (CBCL) syndrome scales of the referred sample (N = 1225), of the general-population sample (N = 3418), and of the total sample. Models estimating 1-class through 5-class solutions were compared and agreement in the classification of subjects was evaluated. Chi square analyses, a logistic regression, and a multinomial logistic regression analysis were used to investigate the relations between classes and diagnoses. In the two samples and in the total sample, the best-fitting models were 4-class solutions. The identified classes were Internalizing Problems (15.68%), Severe Dysregulated (7.82%), Attention/Hyperactivity (10.19%), and Low Problems (66.32%). Subsequent analyses indicated a significant relationship between diagnoses and classes as well as a main association between the severe dysregulated class and comorbidity. Our data suggested the presence of four different psychopathological profiles related to different outcomes in terms of psychopathological diagnoses. In particular, our results underline the presence of a profile characterized by severe emotional and behavioural dysregulation that is mostly associated with the presence of multiple diagnosis.

The Role of Omega-3 Fatty Acids in Developmental Psychopathology: A Systematic Review on Early Psychosis, Autism, and ADHD.

In this systematic review, we will consider and debate studies that have explored the effects of ω-3 polyunsaturated fatty acids (PUFAs) in three major, and somehow related, developmental psychiatric disorders: Autism, Attention Deficit and Hyperactivity disorder and Psychosis. The impact of ω-3 PUFAs on clinical symptoms and, if possible, brain trajectory in children and adolescents suffering from these illnesses will be reviewed and discussed, considering the biological plausibility of the effects of omega-3 fatty acids, together with their potential perspectives in the field. Heterogeneity in study designs will be discussed in the light of differences in results and interpretation of studies carried out so far.

Experimental demonstration of a high-frequency forward scattering acoustic barrier in a dynamic coastal environment.

Detecting a target by measuring its forward scattered field is of interest for harbor surveillance because target strength levels are generally higher in the forward direction than in the backward direction for simple geometries. An acoustic barrier based on forward scattering was demonstrated in a nearly range-independent shallow water environment. The experimental location was characterized by high reverberation, low temporal signal coherence, and, as a result, few stable multipath arrivals due to the fluctuating sea surface. This high-frequency experiment utilized a vertical source array, broadcasting broadside pulses, and a vertical receiver array spanning the water column. The signal of interest was the aberration (in space and time) caused by the acoustic forward scattering field of crossing targets (2-m-long aluminum cylinder, 1-m-diameter steel sphere and pair of scuba tanks). Hence, the spatial and temporal coherence of the recorded acoustic signals was first investigated to assess the stability of the early acoustic arrivals in this rapidly fluctuating coastal environment. A principal component analysis of the stable portion of the recorded acoustic signals was then used to determine the crossing time of the target and to isolate some of its scattered wavefield components.

Interoperability Among Unmanned Maritime Vehicles: Review and First In-field Experimentation.

Complex maritime missions, both above and below the surface, have traditionally been carried out by manned surface ships and submarines equipped with advanced sensor systems. Unmanned Maritime Vehicles (UMVs) are increasingly demonstrating their potential for improving existing naval capabilities due to their rapid deployability, easy scalability, and high reconfigurability, offering a reduction in both operational time and cost. In addition, they mitigate the risk to personnel by leaving the man far-from-the-risk but in-the-loop of decision making. In the long-term, a clear interoperability framework between unmanned systems, human operators, and legacy platforms will be crucial for effective joint operations planning and execution. However, the present multi-vendor multi-protocol solutions in multi-domain UMVs activities are hard to interoperate without common mission control interfaces and communication protocol schemes. Furthermore, the underwater domain presents significant challenges that cannot be satisfied with the solutions developed for terrestrial networks. In this paper, the interoperability topic is discussed blending a review of the technological growth from 2000 onwards with recent authors' in-field experience; finally, important research directions for the future are given. Within the broad framework of interoperability in general, the paper focuses on the aspect of interoperability among UMVs not neglecting the role of the human operator in the loop. The picture emerging from the review demonstrates that interoperability is currently receiving a high level of attention with a great and diverse deal of effort. Besides, the manuscript describes the experience from a sea trial exercise, where interoperability has been demonstrated by integrating heterogeneous autonomous UMVs into the NATO Centre for Maritime Research and Experimentation (CMRE) network, using different robotic middlewares and acoustic modem technologies to implement a multistatic active sonar system. A perspective for the interoperability in marine robotics missions emerges in the paper, through a discussion of current capabilities, in-field experience and future advanced technologies unique to UMVs. Nonetheless, their application spread is slowed down by the lack of human confidence. In fact, an interoperable system-of-systems of autonomous UMVs will require operators involved only at a supervisory level. As trust develops, endorsed by stable and mature interoperability, human monitoring will be diminished to exploit the tremendous potential of fully autonomous UMVs.

Mental health and coping strategies in families of children and young adults with muscular dystrophies.

BACKGROUND: Living with a progressive disease as muscular dystrophy (MD) can be challenging for the patient and the entire family from both emotional and practical point of view. We aimed to extend our previously published data about mental health in patients with MDs, also investigating coping profiles of both themselves and their parents. Furthermore, we wanted to verify whether psychological adaptation of patients can be predicted by coping strategies, taking also into account physical impairment, cognitive level and socioeconomic status. METHODS: 112 patients with MDs, aged 2-32 were included. Their emotional and behavioural features were assessed through parent- and self-report Achenbach System for Empirically Based Assessment questionnaires and Strength and Difficulties Questionnaires. Development and Well-Being Assessment or Autism Diagnostic Observation Schedule were administered to confirm suspected diagnoses. Coping profile of both parents and patients was assessed through the self-administered New Italian Version of the Coping Orientation to the Problems Experienced questionnaire and its relationship with emotional/behavioural outcome was examined in linear regression analyses. RESULTS: High prevalence of intellectual disability and autism spectrum disorders was confirmed in Duchenne MD. Despite the high rate of internalizing symptomatology, we did not report higher rate of psychopathological disorders compared to general population. Parents tend to rely more on positive reinterpretation and less on disengagement coping. Avoidance coping, whether used by parents or patients, and ID, predicted increased emotional/behavioural problems. CONCLUSIONS: Psychosocial interventions should address problems of anxiety and depression that people with MDs frequently experience, even through fostering parents' and childrens' engagement coping over disengagement coping.

Benchmark problems for acoustic scattering from elastic objects in the free field and near the seafloor.

Results from a workshop organized in 2006 to assess the state of the art in target scatter modeling are presented. The problem set includes free-field scenarios as well as scattering from targets that are proud, half-buried, or fully buried in the sediment. The targets are spheres and cylinders, of size O(1 m), which are insonified by incident plane waves in the low-frequency band 0.1-10 kHz. In all cases, the quantity of interest is the far-field target strength. The numerical techniques employed fall within three classes: (i) finite-element (FE) methods and (ii) boundary-element (BE) techniques, with different approaches to computing the far field via discretizations of the Helmholtz-Kirchhoff integral in each case, and (iii) semianalytical methods. Reference solutions are identified for all but one of the seven test problems considered. Overall, FE- and BE-based models emerge as those being capable of treating a wider class of problems in terms of target geometry, with the FE method having the additional advantage of being able to deal with complex internal structures without much additional effort. These capabilities are of value for the study of experimental scenarios, which can essentially be envisioned as variations of the problem set presented here.

Tank measurements of scattering from a resin-filled fiberglass spherical shell with internal flaws.

This paper presents results of acoustic inversion and structural health monitoring achieved by means of low to midfrequency elastic scattering analysis of simple, curved objects, insonified in a water tank. Acoustic elastic scattering measurements were conducted between 15 and 100 kHz on a 60-mm-radius fiberglass spherical shell, filled with a low-shear-speed epoxy resin. Preliminary measurements were conducted also on the void shell before filling, and on a solid sphere of the same material as the filler. These data were used to estimate the constituent material parameters via acoustic inversion. The objects were measured in the backscatter direction, suspended at midwater, and insonified by a broadband directional transducer. From the inspection of the response of the solid-filled shell it was possible to detect and characterize significant inhomogeneities of the interior (air pockets), the presence of which were later confirmed by x-ray CT scan and ultrasound measurements. Elastic wave analysis and a model-data comparison study support the physical interpretation of the measurements.

Computing the far field scattered or radiated by objects inside layered fluid media using approximate Green's functions.

A numerically efficient technique is presented for computing the field radiated or scattered from three-dimensional objects embedded within layered acoustic media. The distance between the receivers and the object of interest is supposed to be large compared to the acoustic wavelength. The method requires the pressure and normal particle displacement on the surface of the object or on an arbitrary circumscribing surface, as an input, together with a knowledge of the layered medium Green's functions. The numerical integration of the full wave number spectral representation of the Green's functions is avoided by employing approximate formulas which are available in terms of elementary functions. The pressure and normal particle displacement on the surface of the object of interest, on the other hand, may be known by analytical or numerical means or from experiments. No restrictions are placed on the location of the object, which may lie above, below, or across the interface between the fluid media. The proposed technique is verified through numerical examples, for which the near field pressure and the particle displacement are computed via a finite-element method. The results are compared to validated reference models, which are based on the full wave number spectral integral Green's function.

A computationally efficient finite element model with perfectly matched layers applied to scattering from axially symmetric objects.

A frequency-domain finite-element (FE) technique for computing the radiation and scattering from axially symmetric fluid-loaded structures subject to a nonsymmetric forcing field is presented. The Berenger perfectly matched layer (PML), applied directly at the fluid-structure interface, makes it possible to emulate the Sommerfeld radiation condition using FE meshes of minimal size. For those cases where the acoustic field is computed over a band of frequencies, the meshing process is simplified by the use of a wavelength-dependent rescaling of the PML coordinates. Quantitative geometry discretization guidelines are obtained from a priori estimates of small-scale structural wavelengths, which dominate the acoustic field at low to mid frequencies. One particularly useful feature of the PML is that it can be applied across the interface between different fluids. This makes it possible to use the present tool to solve problems where the radiating or scattering objects are located inside a layered fluid medium. The proposed technique is verified by comparison with analytical solutions and with validated numerical models. The solutions presented show close agreement for a set of test problems ranging from scattering to underwater propagation.

Assessing mental health in boys with Duchenne muscular dystrophy: Emotional, behavioural and neurodevelopmental profile in an Italian clinical sample.

OBJECTIVE: To evaluate through a comprehensive protocol, the psychopathological profile of DMD boys. The primary aim of this observational study was to describe the emotional and behavioural profile and the neurodevelopmental problems of Italian boys with Duchenne Muscular Dystrophy (DMD); the secondary aim was to explore the relation between psychopathological profile and DMD genotype. METHOD: 47 DMD boys, aged 2-18, were included in the study and assessed through structured and validated tools including Wechsler scales or Griffiths for cognitive ability, Child Behavior Check List (CBCL), Youth Self Report (YSR) and Strengths and Difficulties Questionnaire (SDQ) for emotional and behavioural features. Patients "at risk" based on questionnaires scores were evaluated by a clinical structured interview using Development and Well Being Assessment (DAWBA) or Autism Diagnostic Observation Schedule (ADOS), as required. RESULTS: The 47 enrolled patients, defined with a Full Scale Intelligence Quotient (FSIQ) of 80.38 (one SD below average), and presenting a large and significant difference in FSIQ in relation to the site of mutation along the dystrophin gene (distal mutations associated with a more severe cognitive deficit), were showing Internalizing Problems (23.4%) and Autism Spectrum Disorders (14.8%). Interestingly, an association of internalizing problems with distal deletion of the DMD gene is documented. CONCLUSION: Even though preliminary, these data show that the use of validated clinical instruments, that focus on the impact of emotional/behaviour problems on everyday life, allows to carefully identify clinically significant psychopathology.

Effect of family structure and TPH2 G-703T on the stability of dysregulation profile throughout adolescence.

BACKGROUND: Two different polymorphisms (TPH2 G-703T and 5-HTTLPR) involved in the serotonergic pathway have been reported to play a role, both alone and in interaction with the environment, in early and adult emotion regulation. As most of these studies are cross-sectional, we know little about the impact of these polymorphisms over time, particularly during adolescence. METHODS: Because we were interested in the effects of these polymorphisms and environment (i.e., family structure) at different time-points on the emotional dysregulation profile, we performed a path analysis model in a general adolescent population sample of a five-year follow-up study. RESULTS: We found a high stability of Dysregulation Profile problems independently from the examined allelic variants. We also found that early family structure directly influences the levels of dysregulation problems in early adolescence, both alone and in interaction with TPH2, suggesting the presence of a gene-environment interaction effect. Furthermore, we found that in adolescents homozygous for the TPH2 G allele, the effect of the early family structure remains active during late adolescence, albeit mediated by earlier emotional problems. LIMITATIONS: The high attrition rate, the use of only one source on behavioral problems of adolescents, and the focus on a single polymorphism in the investigated genes could limit the generalizability of the present results. CONCLUSIONS: These results suggest that early family structure could play a significant role in the development and maintenance of emotional and behavioral problems not only in early adolescence but also in late-adolescence, although this effect was mediated and moderated by behavioral and genetic variables.