Detalhe da pesquisa
1.
The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism.
Cell
; 165(7): 1632-1643, 2016 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27315480
2.
Rationally designed chimeric PI3K-BET bromodomain inhibitors elicit curative responses in MYC-driven lymphoma.
Proc Natl Acad Sci U S A
; 120(36): e2306414120, 2023 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37643213
3.
Cathepsin X deficiency alters the processing and localisation of cathepsin L and impairs cleavage of a nuclear cathepsin L substrate.
Biol Chem
; 405(5): 351-365, 2024 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38410910
4.
An extensional strain sensing mechanosome drives adhesion-independent platelet activation at supraphysiological hemodynamic gradients.
BMC Biol
; 20(1): 73, 2022 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35331224
5.
Membrane Permeating Macrocycles: Design Guidelines from Machine Learning.
J Chem Inf Model
; 62(19): 4605-4619, 2022 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36178379
6.
Synthesis and biological evaluation of 4H-benzo[e][1,3]oxazin-4-ones analogues of TGX-221 as inhibitors of PI3Kß.
Bioorg Med Chem
; 69: 116832, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35752141
7.
Enhanced nitric oxide production by macrophages treated with a cell-penetrating peptide conjugate.
Bioorg Chem
; 123: 105763, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35366581
8.
Side-Chain Interactions in d/l Peptide Nanotubes: Studies by Crystallography, NMR Spectroscopy and Molecular Dynamics.
Chemistry
; 27(58): 14489-14500, 2021 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34415083
9.
Lipophilic Salts and Lipid-Based Formulations: Enhancing the Oral Delivery of Octreotide.
Pharm Res
; 38(6): 1125-1137, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34100217
10.
An apically located hybrid guanylate cyclase-ATPase is critical for the initiation of Ca2+ signaling and motility in Toxoplasma gondii.
J Biol Chem
; 294(22): 8959-8972, 2019 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30992368
11.
History, Chemistry and Antibacterial Spectrum.
Adv Exp Med Biol
; 1145: 15-36, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31364069
12.
Controlled Construction of Cyclic dâ /â l Peptide Nanorods.
Angew Chem Int Ed Engl
; 58(2): 596-601, 2019 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30452108
13.
Methionine Ameliorates Polymyxin-Induced Nephrotoxicity by Attenuating Cellular Oxidative Stress.
Antimicrob Agents Chemother
; 62(1)2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29061752
14.
Functional Characterization of the Unique Terminal Thioesterase Domain from Polymyxin Synthetase.
Biochemistry
; 56(4): 657-668, 2017 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28071053
15.
A Novel Serpin Regulatory Mechanism: SerpinB9 IS REVERSIBLY INHIBITED BY VICINAL DISULFIDE BOND FORMATION IN THE REACTIVE CENTER LOOP.
J Biol Chem
; 291(7): 3626-38, 2016 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26670609
16.
Synthesis and biological evaluation of 8-aryl-2-morpholino-7-O-substituted benzo[e][1,3]oxazin-4-ones against DNA-PK, PI3K, PDE3A enzymes and platelet aggregation.
Bioorg Med Chem
; 25(20): 5531-5536, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28838830
17.
Characterization of the Polymyxin D Synthetase Biosynthetic Cluster and Product Profile of Paenibacillus polymyxa ATCC 10401.
J Nat Prod
; 80(5): 1264-1274, 2017 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28463513
18.
Pharmacokinetics of the Individual Major Components of Polymyxin B and Colistin in Rats.
J Nat Prod
; 80(1): 225-229, 2017 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28080060
19.
Design and Evaluation of Novel Polymyxin Fluorescent Probes.
Sensors (Basel)
; 17(11)2017 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29137129
20.
Identification of a Cyanine-Dye Labeled Peptidic Ligand for Y1R and Y4R, Based upon the Neuropeptide Y C-Terminal Analogue, BVD-15.
Bioconjug Chem
; 27(9): 2166-75, 2016 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27513006