Detalhe da pesquisa
1.
Early telomerase inactivation accelerates aging independently of telomere length.
Cell
; 160(5): 928-939, 2015 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25723167
2.
A comprehensive phenotypic CRISPR-Cas9 screen of the ubiquitin pathway uncovers roles of ubiquitin ligases in mitosis.
Mol Cell
; 81(6): 1319-1336.e9, 2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33539788
3.
Alkenyl oxindole is a novel PROTAC moiety that recruits the CRL4DCAF11 E3 ubiquitin ligase complex for targeted protein degradation.
PLoS Biol
; 22(5): e3002550, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38768083
4.
Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat Chem Biol
; 20(4): 503-511, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37932528
5.
Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway.
Nature
; 579(7799): 427-432, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32132707
6.
Effects of photoperiod and temperature on the developmental duration and diapause in Dolycoris baccarum (Heteroptera: Pentatomidae) from Hohhot, Inner Mongolia, China.
J Insect Sci
; 24(2)2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38442351
7.
A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling.
PLoS Genet
; 16(10): e1009103, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33052901
8.
Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation.
J Biol Chem
; 294(50): 18952-18966, 2019 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31578281
9.
Enhanced longevity by ibuprofen, conserved in multiple species, occurs in yeast through inhibition of tryptophan import.
PLoS Genet
; 10(12): e1004860, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25521617
10.
Identification of genetic modifiers enhancing B7-H3-targeting CAR T cell therapy against glioblastoma through large-scale CRISPRi screening.
J Exp Clin Cancer Res
; 43(1): 95, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38561797
11.
Autism genes converge on microtubule biology and RNA-binding proteins during excitatory neurogenesis.
bioRxiv
; 2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38187634
12.
An engineered Cas12i nuclease that is an efficient genome editing tool in animals and plants.
Innovation (Camb)
; 5(2): 100564, 2024 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38379787
13.
CRISPR-based functional genomics screening in human-pluripotent-stem-cell-derived cell types.
Cell Genom
; 3(5): 100300, 2023 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37228745
14.
Protocol for generating in vitro glioma models using human-induced pluripotent- or embryonic-stem-cell-derived cerebral organoids.
STAR Protoc
; 4(3): 102346, 2023 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37421615
15.
Scalable, cell type-selective, AAV-based in vivo CRISPR screening in the mouse brain.
bioRxiv
; 2023 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37398301
16.
CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.
bioRxiv
; 2023 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37398204
17.
Loss of the Novel Myelin Protein CMTM5 in Multiple Sclerosis Lesions and Its Involvement in Oligodendroglial Stress Responses.
Cells
; 12(16)2023 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37626895
18.
A molecular glue approach to control the half-life of CRISPR-based technologies.
bioRxiv
; 2023 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36945568
19.
How many authors does it take to publish a high profile or classic paper?
Mol Biol Cell
; 33(12)2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36137240
20.
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2.
Nat Cell Biol
; 24(1): 24-34, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35027731